Interactor 1: TPM1 (P58771)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: ACTA (P62737)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: Acta2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29199018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Tropomyosin
Common GO terms GO:0005737 - cytoplasm
GO:0015629 - actin cytoskeleton
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 284
Mm

1 377
+ Dm
+ Hs
+ Oc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Dm
+ Dm
+ Hs
+ Mm

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Last updated: 11Aug2025