Protein: FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial (EC 5.3.2.2) (Acylpyruvase FAHD1) (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (FAH domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (ODx) (EC 4.1.1.112) (YisK-like protein)

Gene: FAHD1
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q6P587

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
GO:0006090 - pyruvate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1242601

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

4

1

High-throughput

0.691

High

273071

CLU
Clustered mitochondria protein homolog

4

0

High-throughput

0.661

High

662785

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

3

0

High-throughput

0.638

High

1242610

DHTK1
2-oxoadipate dehydrogenase complex component E1

2

1

High-throughput

0.611

High

1242617

FSD1
Fibronectin type III and SPRY domain-containing protein 1

2

4

High-throughput

0.611

High

278680

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.602

High

1092014

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

0

High-throughput

0.580

High

61954

GTPBA
GTP-binding protein 10

1

1

High-throughput

0.536

High

288965

ERAL1
GTPase Era, mitochondrial

1

2

High-throughput

0.536

High

301912

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

1

High-throughput

0.536

High

425814

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

1

High-throughput

0.536

High

532685

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.536

High

539349

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

3

High-throughput

0.536

High

547155

PYC
Pyruvate carboxylase, mitochondrial

1

1

High-throughput

0.536

High

554808

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

2

High-throughput

0.536

High

653391

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.536

High

725619

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

2

High-throughput

0.536

High

856291

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.536

High

884653

SYHM
Histidine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1043631

COAA1

1

1

High-throughput

0.536

High

1162760

KGUA
Guanylate kinase

1

1

High-throughput

0.536

High

1194746

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

1

High-throughput

0.536

High

1213269

RM02
Large ribosomal subunit protein uL2m

1

1

High-throughput

0.536

High

1235400

ACD10
Acyl-CoA dehydrogenase family member 10

1

1

High-throughput

0.536

High

1242589

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

2

High-throughput

0.536

High

1242595

GUF1
Translation factor GUF1, mitochondrial

1

1

High-throughput

0.536

High

1242602

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.536

High

1242603

FAKD4
FAST kinase domain-containing protein 4

1

2

High-throughput

0.536

High

1242605

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

1

High-throughput

0.536

High

1242606

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

1

High-throughput

0.536

High

1242631

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.536

High

1242634

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

1242645

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

2

High-throughput

0.536

High

954508

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.515

High

61532

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.513

High

66222

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.513

High

75979

B4DEF8
Large ribosomal subunit protein mL45

1

0

High-throughput

0.513

High

134320

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.513

High

166673

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.513

High

177559

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

223838

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.513

High

271063

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

296128

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.513

High

321099

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

322258

GLSK
Glutaminase kidney isoform, mitochondrial

1

0

High-throughput

0.513

High

333676

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.513

High

334425

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

350902

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.513

High

470308

NEP
Neprilysin

1

0

Small-scale

0.513

High

477810

RM03
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.513

High

560880

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

High-throughput

0.513

High

643239

MUTA
Methylmalonyl-CoA mutase, mitochondrial

1

0

High-throughput

0.513

High

686707

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

716123

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

783105

ARL2
ADP-ribosylation factor-like protein 2

1

0

High-throughput

0.513

High

851926

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.513

High

903564

IDH3G
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

1

0

High-throughput

0.513

High

926094

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

932889

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

0

High-throughput

0.513

High

941674

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

High-throughput

0.513

High

1011819

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.513

High

1036109

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

High-throughput

0.513

High

1052956

FOLC
Folylpolyglutamate synthase, mitochondrial

1

0

High-throughput

0.513

High

1061338

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

1093471

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.513

High

1094037

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.513

High

1123323

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

1138848

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1181459

TRM5
tRNA

1

0

High-throughput

0.513

High

1194824

PPCEL
Prolyl endopeptidase-like

1

0

High-throughput

0.513

High

1205715

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

0

High-throughput

0.513

High

1207045

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1215589

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

0

High-throughput

0.513

High

1232848

PTRD1
Putative peptidyl-tRNA hydrolase PTRHD1

1

0

High-throughput

0.513

High

1242584

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1242585

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.513

High

1242590

GLUCM
D-glutamate cyclase, mitochondrial

1

0

High-throughput

0.513

High

1242591

RM55
Large ribosomal subunit protein mL55

1

0

High-throughput

0.513

High

1242592

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1242593

RM41
Large ribosomal subunit protein mL41

1

0

High-throughput

0.513

High

1242594

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.513

High

1242596

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1242597

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

1242598

CHDH
Choline dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1242599

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

1

0

High-throughput

0.513

High

1242600

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.513

High

1242604

RM24
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.513

High

1242607

COQ8B
Atypical kinase COQ8B, mitochondrial

1

0

High-throughput

0.513

High

1242608

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.513

High

1242609

RM48
Large ribosomal subunit protein mL48

1

0

High-throughput

0.513

High

1242611

SYNM
Asparaginyl-tRNA synthetase

1

0

High-throughput

0.513

High

1242612

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.513

High

1242613

MIPEP
Mitochondrial intermediate peptidase

1

0

High-throughput

0.513

High

1242614

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.513

High

1242615

RT63
Large ribosomal subunit protein mL63

1

0

High-throughput

0.513

High

1242616

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.513

High

1242618

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.513

High

1242619

SELO
Protein adenylyltransferase SelO, mitochondrial

1

0

High-throughput

0.513

High

1242620

NUDT9
ADP-ribose pyrophosphatase, mitochondrial

1

0

High-throughput

0.513

High

1242621

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1242622

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.513

High

1242623

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.513

High

1242624

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.513

High

1242625

RM09
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.513

High

1242627

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.513

High

1242628

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.513

High

1242629

RM46
Large ribosomal subunit protein mL46

1

0

High-throughput

0.513

High

1242630

MOD5
tRNA dimethylallyltransferase

1

0

High-throughput

0.513

High

1242633

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.513

High

1242635

RM47
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.513

High

1242636

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.513

High

1242638

RM40
Large ribosomal subunit protein mL40

1

0

High-throughput

0.513

High

1242639

D39U1
Epimerase family protein SDR39U1

1

0

High-throughput

0.513

High

1242640

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.513

High

1242641

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

1242642

RT18A
Large ribosomal subunit protein mL66

1

0

High-throughput

0.513

High

1242643

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.513

High

1242644

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.513

High

1242646

RM35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.513

High

1242647

RM15
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.513

High

1242648

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.513

High

1242649

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.513

High

1242650

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1242651

SARDH
Sarcosine dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1242652

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.513

High

1242653

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1242654

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.513

High

1242655

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.513

High

1242657

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

1242658

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

1242659

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.513

High

1242637

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.508

High

415651

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

451184

NFL
Neurofilament light polypeptide

1

0

High-throughput

0.493

High

1242626

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

1242656

RNF11
RING finger protein 11

1

1

High-throughput

0.470

High

1242588

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.460

High

768458

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

1218974

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.458

High

1242587

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

430047

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1242586

UBR3
E3 ubiquitin-protein ligase UBR3

4

0

High-throughput

0.360

High

248531

O10H3
Olfactory receptor 10H3

2

0

High-throughput

0.318

High

424303

INHA
Inhibin alpha chain

1

0

High-throughput

0.279

Low

301492

WFS1
Wolframin

1

0

High-throughput

0.268

Low

154532

PLPP1
Phospholipid phosphatase 1

1

0

High-throughput

0.251

Low

1141181

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.249

Low

1242632

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025