Protein: ATG4B
Cysteine protease ATG4B (EC 3.4.22.-) (AUT-like 1 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 1) (Autophagin-1) (Autophagy-related protein 4 homolog B) (HsAPG4B) (hAPG4B)

Gene: ATG4B
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q9Y4P1

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0000423 - mitophagy
GO:0004175 - endopeptidase activity
GO:0004197 - cysteine-type endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1326231

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

13

20

Small-scale

0.986

High

891370

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

10

20

Small-scale

0.982

High

1328075

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

8

20

Small-scale

0.978

High

306368

GBRAP
Gamma-aminobutyric acid receptor-associated protein

7

20

Small-scale

0.973

High

1330686

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

8

20

Small-scale

0.967

High

1315816

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

5

20

Small-scale

0.928

High

61909

MP3B2
Microtubule-associated proteins 1A/1B light chain 3 beta 2

1

20

High-throughput

0.691

High

1253356

FANK1
Fibronectin type 3 and ankyrin repeat domains protein 1

3

0

High-throughput

0.638

High

274312

STK16
Serine/threonine-protein kinase 16

2

1

High-throughput

0.628

High

1377888

ATG4B
Cysteine protease ATG4B

1

2

High-throughput

0.575

High

1158537

S27A4
Long-chain fatty acid transport protein 4

1

0

Small-scale

0.537

High

262333

ULK1
Serine/threonine-protein kinase ULK1

1

1

High-throughput

0.536

High

311653

SMC2
Structural maintenance of chromosomes protein 2

1

1

High-throughput

0.536

High

323363

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.536

High

516765

PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

0.536

High

780817

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

1

High-throughput

0.536

High

822404

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.536

High

830512

KC1E
Casein kinase I isoform epsilon

1

1

High-throughput

0.536

High

910785

RS23
Small ribosomal subunit protein uS12

1

1

High-throughput

0.536

High

1020015

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.536

High

1031505

PABP4
Polyadenylate-binding protein 4

1

1

High-throughput

0.536

High

1307079

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.536

High

1328389

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

1

High-throughput

0.536

High

1345676

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

1

High-throughput

0.536

High

177119

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.513

High

181745

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

0

High-throughput

0.513

High

276066

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.513

High

296780

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.513

High

335223

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

401199

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

417050

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

509175

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.513

High

578215

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

616602

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.513

High

631267

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

649850

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

702194

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

722560

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

759908

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.513

High

760415

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

773649

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

782406

KDM5C
Lysine-specific demethylase 5C

1

0

High-throughput

0.513

High

806746

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

807077

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

807276

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

825282

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.513

High

879374

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.513

High

892944

IF4A1
Eukaryotic initiation factor 4A-I

1

0

High-throughput

0.513

High

894994

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.513

High

899893

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.513

High

905788

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.513

High

907611

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

907793

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.513

High

908239

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

911308

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

915134

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

919573

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

920123

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.513

High

920595

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.513

High

920727

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.513

High

922034

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

922490

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

922948

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.513

High

923299

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

928856

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.513

High

949596

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.513

High

951843

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

994415

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.513

High

1019467

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

0

High-throughput

0.513

High

1027461

STK3
Serine/threonine-protein kinase 3

1

0

High-throughput

0.513

High

1049689

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.513

High

1057746

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.513

High

1058329

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

High-throughput

0.513

High

1062907

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

High-throughput

0.513

High

1063389

CND1
Condensin complex subunit 1

1

0

High-throughput

0.513

High

1189979

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.513

High

1199916

KTN1
Kinectin

1

0

High-throughput

0.513

High

1270633

STAM1
Signal transducing adapter molecule 1

1

0

High-throughput

0.513

High

1287305

CC124
Coiled-coil domain-containing protein 124

1

0

High-throughput

0.513

High

1301351

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

0

High-throughput

0.513

High

1309784

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.513

High

1319037

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.513

High

1342897

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.513

High

1345914

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

0

High-throughput

0.513

High

1348518

COA4
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial

1

0

High-throughput

0.513

High

1354233

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.513

High

1377889

PRC2C
Protein PRRC2C

1

0

High-throughput

0.513

High

229164

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

898560

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

973307

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

1172424

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1284214

RAB7B
Ras-related protein Rab-7b

1

1

Small-scale

0.479

High

1356384

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.479

High

175323

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

Small-scale

0.458

High

324694

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

348346

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

376352

ANXA1
Annexin A1

1

0

High-throughput

0.458

High

632455

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

780382

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1037029

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1271006

KAT6A
Histone acetyltransferase KAT6A

1

0

Small-scale

0.458

High

1331726

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1348929

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1354991

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1355084

TES
Testin

1

0

High-throughput

0.458

High

90098

D6RAT0
Small ribosomal subunit protein eS1

1

1

High-throughput

0.445

High

378227

PRIO
Major prion protein

1

0

High-throughput

0.426

High

580158

K2C4
Keratin, type II cytoskeletal 4

1

0

High-throughput

0.426

High

101648

F8VR69
Ribosomal protein L6

1

1

High-throughput

0.407

High

534158

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.279

Low

571252

EGLN
Endoglin

1

0

High-throughput

0.279

Low

722658

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.279

Low

1266383

H1X
Histone H1.10

1

0

High-throughput

0.279

Low

1356664

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.279

Low

101315

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

554150

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

652708

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

1311719

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1139567

SLX4I
Protein SLX4IP

1

0

High-throughput

0.232

Low

1309161

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024