Protein: GSDMA
Gasdermin-A (Gasdermin-1) [Cleaved into: Gasdermin-A, N-terminal (GSDMA-NT); Gasdermin-A, C-terminal (GSDMA-CT)]

Gene: GSDMA
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q96QA5

Gene Ontology (top 5):
GO:0001786 - phosphatidylserine binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0012501 - programmed cell death

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1400660

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.618

High

1156047

ZIC1
Zinc finger protein ZIC 1

2

2

High-throughput

0.574

High

831271

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

132645

UPK1A
Uroplakin-1a

1

1

High-throughput

0.536

High

227179

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

1

High-throughput

0.536

High

564243

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

733418

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

943115

STX17
Syntaxin-17

1

1

High-throughput

0.536

High

1400646

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

2

High-throughput

0.536

High

185228

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.513

High

222390

TSN6
Tetraspanin-6

1

0

High-throughput

0.513

High

255177

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.513

High

292723

RENR
Renin receptor

1

0

High-throughput

0.513

High

325349

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.513

High

352726

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

391655

FRIH
Ferritin heavy chain

1

0

High-throughput

0.513

High

602828

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

867357

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

876386

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.513

High

914871

NDST2
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

1

0

High-throughput

0.513

High

1023861

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

1197491

VWA3B
von Willebrand factor A domain-containing protein 3B

1

0

High-throughput

0.513

High

1315978

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

1349254

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.513

High

1362512

SIA8A
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

1

0

High-throughput

0.513

High

1380521

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.513

High

1392536

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.513

High

1400512

CDK15
Cyclin-dependent kinase 15

1

0

High-throughput

0.513

High

1400650

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

1400656

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1400657

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.513

High

1400659

KLH11
Kelch-like protein 11

1

0

High-throughput

0.513

High

1400667

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.513

High

1400670

RN115
E3 ubiquitin-protein ligase RNF115

1

0

High-throughput

0.513

High

1055632

GABPA
GA-binding protein alpha chain

1

1

High-throughput

0.489

High

1125319

FASTK
Fas-activated serine/threonine kinase

1

2

High-throughput

0.489

High

1400668

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

324198

CE152
Centrosomal protein of 152 kDa

1

1

High-throughput

0.479

High

623493

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.479

High

1137960

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1390282

TRI11
E3 ubiquitin-protein ligase TRIM11

1

1

Small-scale

0.479

High

242647

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

275189

GGCT
Gamma-glutamylcyclotransferase

1

0

High-throughput

0.458

High

372895

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

456830

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

537747

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

649772

SPR2E
Small proline-rich protein 2E

1

0

High-throughput

0.458

High

788466

ACVL1
Activin receptor type-1-like

1

0

Small-scale

0.458

High

888263

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

973539

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

990628

1433Z
14-3-3 protein zeta/delta

1

0

Small-scale

0.458

High

1064471

DSC1
Desmocollin-1

1

0

High-throughput

0.458

High

1149541

CDSN
Corneodesmosin

1

0

High-throughput

0.458

High

1161606

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1246940

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1288563

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1289829

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.458

High

1364212

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1400651

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1400653

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1400655

ANLN
Anillin

1

0

High-throughput

0.458

High

1400664

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

1400669

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

1209535

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

294206

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

1118133

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.437

High

1400658

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.328

High

387599

APOC1
Apolipoprotein C-I

2

0

High-throughput

0.316

High

933983

APOC4
Apolipoprotein C-IV

2

0

High-throughput

0.316

High

213427

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

0

High-throughput

0.288

High

231255

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

288131

FOXH1
Forkhead box protein H1

1

0

High-throughput

0.279

Low

420260

IFNA4
Interferon alpha-4

1

0

High-throughput

0.279

Low

622846

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

0

High-throughput

0.279

Low

666892

CCNC
Cyclin-C

1

0

High-throughput

0.279

Low

943495

DSCR6
Protein ripply3

1

0

High-throughput

0.279

Low

1181338

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

1249538

AMTN
Amelotin

1

0

High-throughput

0.279

Low

1275332

APTX
Aprataxin

1

0

High-throughput

0.279

Low

1290379

MOGT3
2-acylglycerol O-acyltransferase 3

1

0

High-throughput

0.279

Low

1292222

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.279

Low

1292331

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

1293849

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.279

Low

1352348

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

1385190

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1400645

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

1400647

SH23A
SH2 domain-containing protein 3A

1

0

High-throughput

0.279

Low

1400648

RBM42
RNA-binding protein 42

1

0

High-throughput

0.279

Low

1400649

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1400652

HES4
Transcription factor HES-4

1

0

High-throughput

0.279

Low

1400654

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.279

Low

1400661

GSKIP
GSK3B-interacting protein

1

0

High-throughput

0.279

Low

1400662

WRP73
WD repeat-containing protein WRAP73

1

0

High-throughput

0.279

Low

1400663

THA10
THAP domain-containing protein 10

1

0

High-throughput

0.279

Low

1400665

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

1400666

PCOC2
Procollagen C-endopeptidase enhancer 2

1

0

High-throughput

0.279

Low

387632

APOC2
Apolipoprotein C-II

1

0

High-throughput

0.251

Low

1062287

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.249

Low

1115011

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low

1137467

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low

1314371

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.249

Low

1367065

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1368865

RBP56
TATA-binding protein-associated factor 2N

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025