Protein: DHX58
ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)

Gene: DHX58
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q96C10

Gene Ontology (top 5):
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0003677 - DNA binding
GO:0003724 - RNA helicase activity
GO:0003725 - double-stranded RNA binding
GO:0003727 - single-stranded RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

321924

RIGI
Antiviral innate immune response receptor RIG-I

3

18

Small-scale

0.827

High

1286217

IFIH1
Interferon-induced helicase C domain-containing protein 1

3

18

Small-scale

0.827

High

585524

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

12

High-throughput

0.757

High

1183973

DHX30
ATP-dependent RNA helicase DHX30

1

20

High-throughput

0.757

High

1286219

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

20

High-throughput

0.757

High

1286223

DICER
Endoribonuclease Dicer

1

15

High-throughput

0.757

High

322980

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.691

High

172494

NKRF
NF-kappa-B-repressing factor

1

5

High-throughput

0.677

High

1049110

TRI14
Tripartite motif-containing protein 14

1

20

Small-scale

0.647

High

1052729

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

20

Small-scale

0.618

High

1190050

MAVS
Mitochondrial antiviral-signaling protein

1

20

Small-scale

0.618

High

395432

A4
Amyloid-beta precursor protein

2

8

High-throughput

0.602

High

880992

IF6
Eukaryotic translation initiation factor 6

1

2

High-throughput

0.586

High

1286222

AGO2
Protein argonaute-2

1

20

High-throughput

0.586

High

1216178

RN135
E3 ubiquitin-protein ligase RNF135

1

20

Small-scale

0.575

High

1085876

IF16
Gamma-interferon-inducible protein 16

1

15

High-throughput

0.515

High

925967

AP2B1
AP-2 complex subunit beta

1

6

High-throughput

0.494

High

1286218

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.489

High

1286220

CARF
CDKN2A-interacting protein

1

5

High-throughput

0.489

High

129586

TRAF5
TNF receptor-associated factor 5

1

20

Small-scale

0.479

High

971745

IRF8
Interferon regulatory factor 8

1

11

Small-scale

0.479

High

1020856

TRAF2
TNF receptor-associated factor 2

1

20

Small-scale

0.479

High

1024728

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

1193149

SLN11
Schlafen family member 11

1

4

High-throughput

0.479

High

1286221

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

11

Small-scale

0.479

High

1286224

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

347538

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.445

High


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Last updated: 15 Jul 2024