Protein: EIF1B
Eukaryotic translation initiation factor 1b (eIF1b) (Protein translation factor SUI1 homolog GC20)

Gene: EIF1B
Organism: Homo sapiens
Interactions: 181
UniProt ID: O60739

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0006446 - regulation of translational initiation
GO:0016282 - eukaryotic 43S preinitiation complex
GO:0043024 - ribosomal small subunit binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

254549

EIF1
Eukaryotic translation initiation factor 1

1

1

High-throughput

0.618

High

254541

FUS
RNA-binding protein FUS

2

1

High-throughput

0.601

High

254581

RS16
Small ribosomal subunit protein uS9

2

0

High-throughput

0.585

High

254635

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

2

High-throughput

0.553

High

254508

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

2

2

High-throughput

0.549

High

254569

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

2

High-throughput

0.536

High

254566

ATX1
Ataxin-1

1

0

High-throughput

0.518

High

131251

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

1

High-throughput

0.515

High

187833

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

4

High-throughput

0.515

High

254496

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

High-throughput

0.515

High

254504

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.515

High

254548

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

2

High-throughput

0.515

High

254584

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.515

High

254605

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.515

High

254607

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

2

High-throughput

0.515

High

254626

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

2

High-throughput

0.515

High

254505

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

254634

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

187599

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.493

High

254553

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.493

High

254567

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

254571

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.493

High

254577

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.493

High

254595

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.493

High

254619

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.493

High

254652

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.493

High

254659

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.493

High

254499

AATM
Aspartate aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

254510

THIO
Thioredoxin

1

1

High-throughput

0.479

High

254528

HMGB2
High mobility group protein B2

1

2

High-throughput

0.479

High

254551

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

1

High-throughput

0.479

High

254554

RS10
Small ribosomal subunit protein eS10

1

1

High-throughput

0.479

High

254555

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

1

High-throughput

0.479

High

254573

PSA6
Proteasome subunit alpha type-6

1

3

High-throughput

0.479

High

254591

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.479

High

254594

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

1

High-throughput

0.479

High

254598

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

254615

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

254620

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

254625

LARP1
La-related protein 1

1

2

High-throughput

0.479

High

254657

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.479

High

254663

STRAP
Serine-threonine kinase receptor-associated protein

1

2

High-throughput

0.479

High

254665

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

2

High-throughput

0.479

High

254525

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

3

High-throughput

0.470

High

254538

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.470

High

159437

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.464

High

254602

GRSF1
G-rich sequence factor 1

1

0

Small-scale

0.460

High

228120

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

254507

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

254513

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

254529

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

254530

CALR
Calreticulin

1

0

High-throughput

0.458

High

254540

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

254542

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.458

High

254545

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

254546

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

254550

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

254556

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

254560

GDIB
Rab GDP dissociation inhibitor beta

1

0

High-throughput

0.458

High

254578

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

254582

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.458

High

254586

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.458

High

254587

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

254588

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

0

High-throughput

0.458

High

254589

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

254590

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

254599

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.458

High

254610

IF4H
Eukaryotic translation initiation factor 4H

1

0

High-throughput

0.458

High

254611

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

254614

TSN
Translin

1

0

High-throughput

0.458

High

254618

FSCN1
Fascin

1

0

High-throughput

0.458

High

254627

LYRIC
Protein LYRIC

1

0

High-throughput

0.458

High

254630

RM43
Large ribosomal subunit protein mL43

1

0

High-throughput

0.458

High

254638

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.458

High

254641

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

254664

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

142661

TRI38
E3 ubiquitin-protein ligase TRIM38

1

1

High-throughput

0.439

High

165212

PSA7
Proteasome subunit alpha type-7

1

2

High-throughput

0.437

High

254501

OAT
Ornithine aminotransferase, mitochondrial

1

1

High-throughput

0.437

High

254503

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.437

High

254516

MIF
Macrophage migration inhibitory factor

1

1

High-throughput

0.437

High

254522

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.437

High

254523

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.437

High

254526

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.437

High

254527

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.437

High

254532

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.437

High

254533

DOPD
D-dopachrome decarboxylase

1

1

High-throughput

0.437

High

254536

KCY
UMP-CMP kinase

1

1

High-throughput

0.437

High

254558

PSB3
Proteasome subunit beta type-3

1

1

High-throughput

0.437

High

254565

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.437

High

254568

KAD2
Adenylate kinase 2, mitochondrial

1

1

High-throughput

0.437

High

254596

SET
Protein SET

1

1

High-throughput

0.437

High

254603

TP53B
TP53-binding protein 1

1

1

High-throughput

0.437

High

254606

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.437

High

254609

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

3

High-throughput

0.437

High

254616

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

1

High-throughput

0.437

High

254622

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

254633

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

254637

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

254643

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

3

High-throughput

0.437

High

254650

Q9NZ23
glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.437

High

254654

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

254658

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

2

High-throughput

0.437

High

254661

NUDC
Nuclear migration protein nudC

1

1

High-throughput

0.437

High

254502

HG2A
HLA class II histocompatibility antigen gamma chain

1

1

High-throughput

0.407

High

254629

DDX60
Probable ATP-dependent RNA helicase DDX60

1

1

High-throughput

0.407

High

254651

SPG21
Maspardin

2

0

High-throughput

0.316

High

254547

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.282

High

254509

POTEI
POTE ankyrin domain family member I

1

0

High-throughput

0.279

Low

254600

EF1A2
Elongation factor 1-alpha 2

1

0

High-throughput

0.279

Low

254498

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.269

Low

254519

ML12A
Myosin regulatory light chain 12A

1

0

High-throughput

0.269

Low

254520

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

0

High-throughput

0.269

Low

254539

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.269

Low

254543

TAGL2
Transgelin-2

1

0

High-throughput

0.269

Low

254561

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.269

Low

254575

ARP3
Actin-related protein 3

1

0

High-throughput

0.269

Low

254583

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.269

Low

254612

ELOC
Elongin-C

1

0

High-throughput

0.269

Low

123203

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.249

Low

129927

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.249

Low

162300

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.249

Low

214151

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

0

High-throughput

0.249

Low

254497

FA8
Coagulation factor VIII

1

0

High-throughput

0.249

Low

254500

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.249

Low

254506

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.249

Low

254511

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.249

Low

254512

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.249

Low

254514

PLST
Plastin-3

1

0

High-throughput

0.249

Low

254515

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

254517

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.249

Low

254521

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.249

Low

254524

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

0

High-throughput

0.249

Low

254531

TKT
Transketolase

1

0

High-throughput

0.249

Low

254534

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.249

Low

254535

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

254537

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.249

Low

254544

TALDO
Transaldolase

1

0

High-throughput

0.249

Low

254552

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.249

Low

254557

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.249

Low

254559

SPS1
Selenide, water dikinase 1

1

0

High-throughput

0.249

Low

254562

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.249

Low

254563

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

0

High-throughput

0.249

Low

254564

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.249

Low

254570

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.249

Low

254572

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.249

Low

254574

DEST
Destrin

1

0

High-throughput

0.249

Low

254576

ARP2
Actin-related protein 2

1

0

High-throughput

0.249

Low

254579

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.249

Low

254580

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.249

Low

254592

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.249

Low

254593

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.249

Low

254597

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.249

Low

254601

RBBP4
Histone-binding protein RBBP4

1

0

High-throughput

0.249

Low

254604

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.249

Low

254608

MELT
Ventricular zone-expressed PH domain-containing protein homolog 1

1

0

High-throughput

0.249

Low

254613

RHEB
GTP-binding protein Rheb

1

0

High-throughput

0.249

Low

254617

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.249

Low

254621

Q5SQT9
small monomeric GTPase

1

0

High-throughput

0.249

Low

254623

Q6FGD7
Tubulin-specific chaperone A

1

0

High-throughput

0.249

Low

254624

Q6FGG2
VAMP3 protein

1

0

High-throughput

0.249

Low

254628

Q86YL1
Putative HTH DNA-binding protein

1

0

High-throughput

0.249

Low

254631

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

254632

PARD3
Partitioning defective 3 homolog

1

0

High-throughput

0.249

Low

254636

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.249

Low

254639

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.249

Low

254640

PSB7
Proteasome subunit beta type-7

1

0

High-throughput

0.249

Low

254642

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.249

Low

254644

NAA50
N-alpha-acetyltransferase 50

1

0

High-throughput

0.249

Low

254645

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

254646

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.249

Low

254647

MXRA5
Matrix-remodeling-associated protein 5

1

0

High-throughput

0.249

Low

254648

ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

1

0

High-throughput

0.249

Low

254649

HYPK
Huntingtin-interacting protein K

1

0

High-throughput

0.249

Low

254653

TRM7
tRNA

1

0

High-throughput

0.249

Low

254655

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.249

Low

254656

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

254660

RUVB1
RuvB-like 1

1

0

High-throughput

0.249

Low

254662

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.249

Low

254585

RHOB
Rho-related GTP-binding protein RhoB

1

0

Small-scale

0.238

Low

254518

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025