Protein: ITB2
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)

Gene: ITB2, ITGB2
Organism: Homo sapiens
Interactions: 67
UniProt ID: P05107

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001774 - microglial cell activation
GO:0001851 - complement component C3b binding
GO:0005178 - integrin binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396607

ITAM
Integrin alpha-M

3

20

Small-scale

0.839

High

396612

ITAX
Integrin alpha-X

2

20

Small-scale

0.800

High

396603

ICAM1
Intercellular adhesion molecule 1

5

6

Small-scale

0.710

High

396633

CYH1
Cytohesin-1

4

1

Small-scale

0.696

High

396611

ITAL
Integrin alpha-L

1

20

Small-scale

0.665

High

337756

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.653

High

396638

NT2NA
Notch homolog 2 N-terminal-like protein A

4

13

High-throughput

0.644

High

396627

ITAD
Integrin alpha-D

1

20

Small-scale

0.618

High

396635

CD226
CD226 antigen

1

6

Small-scale

0.618

High

396651

JAM3
Junctional adhesion molecule C

1

6

Small-scale

0.618

High

66947

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.606

High

276300

UPK1B
Uroplakin-1b

2

20

High-throughput

0.606

High

396632

K1H1
Keratin, type I cuticular Ha1

2

7

High-throughput

0.606

High

396637

ATL4
ADAMTS-like protein 4

2

1

High-throughput

0.606

High

396621

RACK1
Small ribosomal subunit protein RACK1

1

4

Small-scale

0.586

High

396645

RANB9
Ran-binding protein 9

1

3

Small-scale

0.586

High

396614

1433B
14-3-3 protein beta/alpha

2

4

Small-scale

0.584

High

396616

KSYK
Tyrosine-protein kinase SYK

2

20

Small-scale

0.584

High

396640

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.580

High

396643

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.580

High

396649

APOL2
Apolipoprotein L2

2

0

High-throughput

0.580

High

396653

MS4A7
Membrane-spanning 4-domains subfamily A member 7

2

0

High-throughput

0.580

High

396655

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.580

High

396659

TLN2
Talin-2

1

16

Small-scale

0.578

High

396615

RADI
Radixin

1

8

Small-scale

0.561

High

396625

UPAR
Urokinase plasminogen activator surface receptor

2

0

Small-scale

0.559

High

396619

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.553

High

396648

DOK1
Docking protein 1

1

4

Small-scale

0.553

High

396629

FHL2
Four and a half LIM domains protein 2

1

9

Small-scale

0.552

High

396654

SHRPN
Sharpin

1

2

Small-scale

0.536

High

396617

CD151
CD151 antigen

1

20

High-throughput

0.536

High

396623

AMPD3
AMP deaminase 3

1

1

High-throughput

0.536

High

396641

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.536

High

396644

SREC2
Scavenger receptor class F member 2

1

9

High-throughput

0.536

High

396652

TX101
Testis-expressed protein 101

1

2

High-throughput

0.536

High

396642

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.529

High

344616

CO3
Complement C3

1

2

Small-scale

0.527

High

337304

ABL1
Tyrosine-protein kinase ABL1

1

12

Small-scale

0.515

High

396634

BGH3
Transforming growth factor-beta-induced protein ig-h3

1

1

Small-scale

0.515

High

396647

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.513

High

396650

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.513

High

396656

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.513

High

345168

KNG1
Kininogen-1

1

3

Small-scale

0.501

High

396602

KPCG
Protein kinase C gamma type

1

14

Small-scale

0.501

High

396604

KPCB
Protein kinase C beta type

1

13

Small-scale

0.501

High

396610

KPCA
Protein kinase C alpha type

1

13

Small-scale

0.501

High

396624

KPCE
Protein kinase C epsilon type

1

13

Small-scale

0.501

High

396626

KPCD
Protein kinase C delta type

1

13

Small-scale

0.501

High

198368

KLK10
Kallikrein-10

1

6

High-throughput

0.489

High

396605

LYN
Tyrosine-protein kinase Lyn

1

12

Small-scale

0.479

High

396608

PLSL
Plastin-2

1

17

High-throughput

0.479

High

396609

VAV
Proto-oncogene vav

1

2

Small-scale

0.479

High

396613

1433T
14-3-3 protein theta

1

4

Small-scale

0.479

High

396620

1433Z
14-3-3 protein zeta/delta

1

4

Small-scale

0.479

High

396622

X3CL1
Fractalkine

1

4

Small-scale

0.479

High

396630

FAK2
Protein-tyrosine kinase 2-beta

1

19

Small-scale

0.479

High

396631

ICAM4
Intercellular adhesion molecule 4

1

3

Small-scale

0.479

High

396606

NT2NC
Notch homolog 2 N-terminal-like protein C

1

13

High-throughput

0.470

High

396628

KEAP1
Kelch-like ECH-associated protein 1

1

1

High-throughput

0.470

High

315874

VNN2
Pantetheine hydrolase VNN2

1

0

Small-scale

0.458

High

396646

CYH2
Cytohesin-2

1

1

Small-scale

0.457

High

396639

CD177
CD177 antigen

1

2

Small-scale

0.445

High

458

NBPFJ
Neuroblastoma breakpoint family member 19

1

6

High-throughput

0.439

High

396657

SCML1
Sex comb on midleg-like protein 1

2

0

High-throughput

0.316

High

396658

CSN3
COP9 signalosome complex subunit 3

1

0

Small-scale

0.288

High

396636

FX4L6
Forkhead box protein D4-like 6

1

0

High-throughput

0.268

Low

396618

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024