Protein: FBX46
F-box only protein 46 (F-box only protein 34-like)

Gene: FBX46, FBXO46
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q6PJ61

Gene Ontology (top 5):
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992221

SKP1
S-phase kinase-associated protein 1

10

1

Small-scale

0.975

High

1112558

CUL1
Cullin-1

4

1

Small-scale

0.873

High

242035

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.517

High

1082551

NEXN
Nexilin

1

1

High-throughput

0.489

High

1245029

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.489

High

1245032

EMIL1
EMILIN-1

1

1

High-throughput

0.489

High

1245027

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1245030

FSD1
Fibronectin type III and SPRY domain-containing protein 1

2

0

High-throughput

0.318

High

1245028

CSN5
COP9 signalosome complex subunit 5

2

0

Small-scale

0.313

High

123740

MYO1C
Unconventional myosin-Ic

1

0

High-throughput

0.279

Low

562612

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.279

Low

616763

SDC1
Syndecan-1

1

0

High-throughput

0.279

Low

866731

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.279

Low

1245025

S2541
Mitochondrial carrier protein SCaMC-3L

1

0

High-throughput

0.279

Low

1245026

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.279

Low

848884

MAGAB
Melanoma-associated antigen 11

1

0

High-throughput

0.251

Low

214855

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

0

Small-scale

0.249

Low

401011

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

414048

P53
Cellular tumor antigen p53

1

0

Small-scale

0.249

Low

608639

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

Small-scale

0.249

Low

610725

TCPA
T-complex protein 1 subunit alpha

1

0

Small-scale

0.249

Low

755737

MCM4
DNA replication licensing factor MCM4

1

0

Small-scale

0.249

Low

1024644

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1040151

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

0

Small-scale

0.249

Low

1062515

DHX9
ATP-dependent RNA helicase A

1

0

Small-scale

0.249

Low

1245024

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

0

High-throughput

0.249

Low

1245031

RUVB1
RuvB-like 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025