Protein: FEZ1
Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1)

Gene: FEZ1
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q99689

Gene Ontology (top 5):
GO:0005080 - protein kinase C binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005813 - centrosome
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1406435

SCOC
Short coiled-coil protein

4

3

Small-scale

0.692

High

843908

HD
Huntingtin

3

1

High-throughput

0.669

High

1316867

ASPM
Abnormal spindle-like microcephaly-associated protein

3

1

High-throughput

0.662

High

1162657

DGKD
Diacylglycerol kinase delta

3

0

High-throughput

0.634

High

1406429

SELN
Selenoprotein N

3

0

High-throughput

0.634

High

920229

PLK1
Serine/threonine-protein kinase PLK1

2

1

High-throughput

0.628

High

170309

AURKA
Aurora kinase A

2

0

High-throughput

0.602

High

931285

AT12A
Potassium-transporting ATPase alpha chain 2

2

0

High-throughput

0.602

High

1091448

ANK3
Ankyrin-3

2

0

High-throughput

0.602

High

1402095

IF140
Intraflagellar transport protein 140 homolog

2

0

High-throughput

0.602

High

1406428

LANC2
LanC-like protein 2

2

0

High-throughput

0.602

High

1406440

MYO5A
Unconventional myosin-Va

2

0

High-throughput

0.602

High

389877

TTHY
Transthyretin

2

1

High-throughput

0.566

High

1331129

PDCD7
Programmed cell death protein 7

2

1

Small-scale

0.559

High

1259271

MED25
Mediator of RNA polymerase II transcription subunit 25

2

1

High-throughput

0.558

High

155797

TXND9
Thioredoxin domain-containing protein 9

1

0

High-throughput

0.558

High

1400365

NEK1
Serine/threonine-protein kinase Nek1

1

1

Small-scale

0.552

High

1352975

CE192
Centrosomal protein of 192 kDa

2

1

High-throughput

0.552

High

326978

UBE4B
Ubiquitin conjugation factor E4 B

1

0

Small-scale

0.537

High

1294986

PTOV1
Prostate tumor-overexpressed gene 1 protein

1

1

High-throughput

0.536

High

1406424

Q9HCK3
KIAA1569 protein

2

1

High-throughput

0.533

High

1406426

DISC1
Disrupted in schizophrenia 1 protein

1

0

Small-scale

0.529

High

270973

CLAP2
CLIP-associating protein 2

1

1

Small-scale

0.527

High

1311643

KIBRA
Protein KIBRA

1

1

Small-scale

0.527

High

1406416

FEZ1
Fasciculation and elongation protein zeta-1

1

1

Small-scale

0.527

High

340222

PCNT
Pericentrin

1

0

High-throughput

0.518

High

1102747

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

High-throughput

0.518

High

1115951

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.518

High

1208196

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

1

0

High-throughput

0.518

High

1244412

BORA
Protein aurora borealis

1

0

High-throughput

0.518

High

1294718

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.518

High

1314767

DI3L2
DIS3-like exonuclease 2

1

0

High-throughput

0.518

High

593197

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

1058616

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.513

High

1134041

ZN638
Zinc finger protein 638

1

0

High-throughput

0.513

High

1229854

CYTSA
Cytospin-A

1

0

High-throughput

0.513

High

1406417

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.508

High

928217

HAP1
Huntingtin-associated protein 1

1

0

High-throughput

0.504

High

1392039

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

Small-scale

0.504

High

636758

PTN
Pleiotrophin

1

0

High-throughput

0.486

High

1406422

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.486

High

1406431

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.484

High

1133357

NC2A
Dr1-associated corepressor

1

1

Small-scale

0.481

High

1406423

SP30L
Histone deacetylase complex subunit SAP30L

1

1

Small-scale

0.481

High

1406430

RAI14
Ankycorbin

1

2

Small-scale

0.481

High

1406436

SMC3
Structural maintenance of chromosomes protein 3

1

1

Small-scale

0.481

High

342302

BRD1
Bromodomain-containing protein 1

1

1

Small-scale

0.481

High

1139370

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

1

Small-scale

0.481

High

1271948

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

Small-scale

0.481

High

1406434

FEZ2
Fasciculation and elongation protein zeta-2

1

1

Small-scale

0.481

High

279211

ULK1
Serine/threonine-protein kinase ULK1

1

1

Small-scale

0.479

High

1051297

KPCZ
Protein kinase C zeta type

1

2

Small-scale

0.479

High

993305

ACTG
Actin, cytoplasmic 2

1

0

Small-scale

0.458

High

1028357

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

318381

MYO1D
Unconventional myosin-Id

1

1

High-throughput

0.445

High

1405661

NECD
Necdin

1

2

High-throughput

0.445

High

1187131

TBC25
TBC1 domain family member 25

1

1

Small-scale

0.439

High

1288370

TLK2
Serine/threonine-protein kinase tousled-like 2

1

1

Small-scale

0.439

High

1406418

ZN251
Zinc finger protein 251

1

1

Small-scale

0.439

High

1385051

CHP3
Calcineurin B homologous protein 3

1

0

High-throughput

0.438

High

194847

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.426

High

399511

C4BPA
C4b-binding protein alpha chain

1

0

High-throughput

0.426

High

633429

ANPRB
Atrial natriuretic peptide receptor 2

1

0

High-throughput

0.426

High

1241159

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.426

High

1313742

MILK2
MICAL-like protein 2

1

0

High-throughput

0.426

High

1406425

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

3

0

High-throughput

0.345

High

1250879

ZY11A
Protein zyg-11 homolog A

2

0

High-throughput

0.328

High

1334314

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

0

High-throughput

0.328

High

1406419

NELFA
Negative elongation factor A

2

0

High-throughput

0.328

High

1406438

KLDC2
Kelch domain-containing protein 2

2

0

High-throughput

0.328

High

1406439

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

2

0

High-throughput

0.323

High

1159329

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.292

High

1128807

NBR1
Next to BRCA1 gene 1 protein

1

0

Small-scale

0.288

High

225333

HTSF1
17S U2 SnRNP complex component HTATSF1

1

0

High-throughput

0.282

High

377271

PTHY
Parathyroid hormone

1

0

High-throughput

0.282

High

452381

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.282

High

750467

CSTF2
Cleavage stimulation factor subunit 2

1

0

High-throughput

0.282

High

770416

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.282

High

873995

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.282

High

885944

STAR
Steroidogenic acute regulatory protein, mitochondrial

1

0

High-throughput

0.282

High

1009609

CCL7
C-C motif chemokine 7

1

0

High-throughput

0.282

High

1120087

CO9A2

1

0

High-throughput

0.282

High

1147669

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.282

High

1406427

OLFL3
Olfactomedin-like protein 3

1

0

High-throughput

0.282

High

1406432

TKNK
Tachykinin-3

1

0

High-throughput

0.282

High

1406442

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.282

High

134366

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

895638

SERPH
Serpin H1

1

0

High-throughput

0.265

Low

1164526

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.265

Low

1204172

MEST
Mesoderm-specific transcript homolog protein

1

0

High-throughput

0.265

Low

1212445

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.265

Low

1406420

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.265

Low

1406421

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.265

Low

773967

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.232

Low

1406433

BAP29
B-cell receptor-associated protein 29

1

0

High-throughput

0.232

Low

1406437

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.232

Low

1406441

TBL2
Transducin beta-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025