Protein: SETMR
Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion protein) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.357); Transposon Hsmar1 transposase (EC 3.1.-.-)]

Gene: SETMR, SETMAR
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q53H47

Gene Ontology (top 5):
GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000729 - DNA double-strand break processing
GO:0003677 - DNA binding
GO:0003690 - double-stranded DNA binding
GO:0003697 - single-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1199858

SETMR
Histone-lysine N-methyltransferase SETMAR

3

14

Small-scale

0.850

High

1199859

H3C
Histone H3.3C

1

20

High-throughput

0.656

High

1199867

IKZF3
Zinc finger protein Aiolos

3

0

High-throughput

0.638

High

537281

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.628

High

1199868

PRP19
Pre-mRNA-processing factor 19

2

8

Small-scale

0.624

High

1199860

SETX
Probable helicase senataxin

2

0

High-throughput

0.602

High

542541

TOP2A
DNA topoisomerase 2-alpha

2

2

Small-scale

0.584

High

171074

VP26C
Vacuolar protein sorting-associated protein 26C

1

1

High-throughput

0.541

High

1146695

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.536

High

1146912

PCBP2
Poly(rC)-binding protein 2

1

3

High-throughput

0.536

High

1199861

LEO1
RNA polymerase-associated protein LEO1

1

1

High-throughput

0.536

High

1199863

APBP2
Amyloid protein-binding protein 2

1

2

High-throughput

0.536

High

818742

CAPG
Macrophage-capping protein

1

0

High-throughput

0.513

High

1199862

TRUB1
Pseudouridylate synthase TRUB1

1

0

High-throughput

0.513

High

909027

NEK4
Serine/threonine-protein kinase Nek4

1

2

High-throughput

0.489

High

551079

PCNA
Proliferating cell nuclear antigen

1

2

Small-scale

0.479

High

776289

SOX11
Transcription factor SOX-11

1

15

Small-scale

0.479

High

163116

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.458

High

1104908

XRCC4
DNA repair protein XRCC4

1

0

Small-scale

0.458

High

1199864

RAD9A
Cell cycle checkpoint control protein RAD9A

1

0

Small-scale

0.458

High

1199865

YJU2
Splicing factor YJU2

4

0

Small-scale

0.362

High

1122789

DOC2A
Double C2-like domain-containing protein alpha

1

0

High-throughput

0.279

Low

1147042

ELOC
Elongin-C

1

0

High-throughput

0.279

Low

1147172

ELOB
Elongin-B

1

0

High-throughput

0.279

Low

1178167

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1199866

BAP29
B-cell receptor-associated protein 29

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025