Protein: EME1
Crossover junction endonuclease EME1 (EC 3.1.22.-) (MMS4 homolog) (hMMS4)

Gene: EME1
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q96AY2

Gene Ontology (top 5):
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000792 - heterochromatin
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1284703

MUS81
Crossover junction endonuclease MUS81

17

3

Small-scale

0.986

High

1222506

SLX4
Structure-specific endonuclease subunit SLX4

7

0

Small-scale

0.721

High

395420

A4
Amyloid-beta precursor protein

3

0

High-throughput

0.642

High

1223003

FANCM
Fanconi anemia group M protein

1

2

Small-scale

0.618

High

1272208

XPF
DNA repair endonuclease XPF

1

2

Small-scale

0.618

High

1169851

I23O2
Indoleamine 2,3-dioxygenase 2

2

0

High-throughput

0.602

High

1284707

SLX1
Structure-specific endonuclease subunit SLX1

2

0

Small-scale

0.592

High

902710

SUMO2
Small ubiquitin-related modifier 2

2

0

Small-scale

0.577

High

1284712

NGN3
Neurogenin-3

2

1

High-throughput

0.574

High

319960

HERC2
E3 ubiquitin-protein ligase HERC2

2

0

High-throughput

0.547

High

639039

S100P
Protein S100-P

1

1

High-throughput

0.536

High

1087326

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.515

High

1274397

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.515

High

317492

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.513

High

607833

USF1
Upstream stimulatory factor 1

1

0

High-throughput

0.513

High

668891

PML
Protein PML

1

0

High-throughput

0.513

High

773486

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

805755

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

962270

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

1224862

FAM9B
Protein FAM9B

1

0

High-throughput

0.513

High

1284704

INT14
Integrator complex subunit 14

1

0

High-throughput

0.513

High

661382

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1082321

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.480

High

524579

LYL1
Protein lyl-1

1

1

High-throughput

0.479

High

918589

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

1284705

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

1

Small-scale

0.479

High

556941

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

749757

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

917713

H4
Histone H4

1

0

High-throughput

0.458

High

1244415

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

1269161

RAD54
DNA repair and recombination protein RAD54-like

1

0

Small-scale

0.458

High

1284702

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

764404

FEN1
Flap endonuclease 1

1

1

Small-scale

0.445

High

1066505

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1284701

RBM33
RNA-binding protein 33

3

0

High-throughput

0.347

High

1284711

KLK5
Kallikrein-5

3

0

High-throughput

0.347

High

134748

CCL22
C-C motif chemokine 22

2

0

High-throughput

0.328

High

180399

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

1113824

GRDN
Girdin

1

0

High-throughput

0.279

Low

1230158

CNTRB
Centrobin

1

0

High-throughput

0.279

Low

1246688

KI18A
Kinesin-like protein KIF18A

1

0

High-throughput

0.279

Low

1267348

TICN2
Testican-2

1

0

High-throughput

0.279

Low

1282303

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1284706

SORT
Sortilin

1

0

High-throughput

0.279

Low

1284708

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.279

Low

1284709

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.279

Low

1284710

INTU
Protein inturned

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024