Protein: PPM1E
Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA)

Gene: PPM1E
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q8WY54

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1361421

TNIK
TRAF2 and NCK-interacting protein kinase

2

9

High-throughput

0.743

High

938119

ANM2
Protein arginine N-methyltransferase 2

3

1

High-throughput

0.667

High

1095425

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

19

Small-scale

0.647

High

960507

PSME3
Proteasome activator complex subunit 3

3

0

High-throughput

0.646

High

1086548

TROP
Trophinin

2

3

High-throughput

0.628

High

930764

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

18

Small-scale

0.618

High

904349

BRCA2
Breast cancer type 2 susceptibility protein

2

0

High-throughput

0.602

High

1206295

PSMG4
Proteasome assembly chaperone 4

2

0

High-throughput

0.602

High

1253913

FA83H
Protein FAM83H

2

0

High-throughput

0.602

High

1361415

PSMG3
Proteasome assembly chaperone 3

2

0

High-throughput

0.602

High

1361416

PIP30
PSME3-interacting protein

2

0

High-throughput

0.602

High

424978

ADT2
ADP/ATP translocase 2

1

1

High-throughput

0.536

High

530134

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.536

High

560031

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.536

High

651845

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.536

High

682562

S100P
Protein S100-P

1

2

High-throughput

0.536

High

1096128

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.536

High

1099741

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.536

High

1281571

SLN11
Schlafen family member 11

1

1

High-throughput

0.536

High

1361413

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.513

High

1121966

ARHG7
Rho guanine nucleotide exchange factor 7

1

2

Small-scale

0.501

High

412340

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

696064

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

1254843

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

844845

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.445

High

1361420

S39A9
Zinc transporter ZIP9

1

3

High-throughput

0.445

High

1361419

S22AB
Solute carrier family 22 member 11

1

1

High-throughput

0.407

High

1216268

NDUF5
Arginine-hydroxylase NDUFAF5, mitochondrial

3

0

High-throughput

0.347

High

874831

SPB4
Serpin B4

2

0

High-throughput

0.328

High

1361418

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.307

High

137773

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.279

Low

254300

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

1

0

High-throughput

0.279

Low

520943

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.279

Low

755502

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

903755

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.279

Low

943104

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

1361414

HS12B
Heat shock 70 kDa protein 12B

1

0

High-throughput

0.279

Low

1141831

EEA1
Early endosome antigen 1

1

0

High-throughput

0.249

Low

1361417

GLOD4
Glyoxalase domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025