Protein: CYAC3
Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3 (EC 7.2.1.3) (Cytochrome b ascorbate-dependent protein 3) (Cytochrome b561 family member A3) (Lysosomal cytochrome b) (LCytb)

Gene: CYAC3, CYB561A3
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q8NBI2

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0005765 - lysosomal membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0016491 - oxidoreductase activity
GO:0031902 - late endosome membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1333405

RNF5
E3 ubiquitin-protein ligase RNF5

3

2

High-throughput

0.616

High

683286

TNR5
Tumor necrosis factor receptor superfamily member 5

2

1

High-throughput

0.606

High

1290519

LAP4B
Lysosomal-associated transmembrane protein 4B

2

0

High-throughput

0.580

High

1333407

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

2

0

High-throughput

0.580

High

138568

CLD5
Claudin-5

2

3

High-throughput

0.553

High

194722

FFAR2
Free fatty acid receptor 2

2

1

High-throughput

0.553

High

258652

G37L1
G-protein coupled receptor 37-like 1

2

1

High-throughput

0.553

High

337895

CLD7
Claudin-7

2

3

High-throughput

0.553

High

549831

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

2

High-throughput

0.553

High

1108972

AQP6
Aquaporin-6

2

5

High-throughput

0.553

High

1228196

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

2

3

High-throughput

0.553

High

1333400

GP152
Probable G-protein coupled receptor 152

2

2

High-throughput

0.553

High

1333401

GPX8
Probable glutathione peroxidase 8

2

3

High-throughput

0.553

High

1333402

T4S18
Transmembrane 4 L6 family member 18

2

1

High-throughput

0.553

High

1333403

RN185
E3 ubiquitin-protein ligase RNF185

2

2

High-throughput

0.553

High

1333404

GP101
Probable G-protein coupled receptor 101

2

1

High-throughput

0.553

High

1333408

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.481

High

1063985

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.470

High

580807

PVR
Poliovirus receptor

2

0

High-throughput

0.316

High

688593

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

0

High-throughput

0.316

High

1187401

SHSL1
Protein shisa-like-1

2

0

High-throughput

0.316

High

1333406

HERP2
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein

2

0

High-throughput

0.316

High

625866

AOC1
Diamine oxidase [copper-containing]

1

0

High-throughput

0.251

Low

1207722

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025