Protein: FBXL3
F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A)

Gene: FBXL3
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q9UKT7

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992389

SKP1
S-phase kinase-associated protein 1

9

3

Small-scale

0.971

High

1112786

CUL1
Cullin-1

6

3

Small-scale

0.931

High

1193577

CRY2
Cryptochrome-2

7

7

Small-scale

0.751

High

1157692

CRY1
Cryptochrome-1

7

7

Small-scale

0.747

High

871766

RFX2
DNA-binding protein RFX2

3

1

High-throughput

0.667

High

651110

RFX1
MHC class II regulatory factor RFX1

3

1

High-throughput

0.609

High

1131714

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

2

0

High-throughput

0.602

High

1294193

CEP57
Centrosomal protein of 57 kDa

2

0

High-throughput

0.580

High

1448396

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1460544

MSRA
Mitochondrial peptide methionine sulfoxide reductase

2

0

High-throughput

0.580

High

185120

TELT
Telethonin

1

2

Small-scale

0.552

High

1429750

ADT4
ADP/ATP translocase 4

1

0

High-throughput

0.513

High

883363

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

Small-scale

0.501

High

982360

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

0

Small-scale

0.480

High

462032

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

468904

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

974912

BTG1
Protein BTG1

1

1

Small-scale

0.479

High

1008538

BTG2
Protein BTG2

1

1

Small-scale

0.479

High

214061

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

Small-scale

0.458

High

1291271

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

Small-scale

0.458

High

1397544

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1328147

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.279

Low

294512

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

139342

UPK2
Uroplakin-2

1

0

High-throughput

0.232

Low

262338

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low

754123

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025