Protein: SYCM
Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)

Gene: SYCM, CARS2
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q9HA77

Gene Ontology (top 5):
GO:0004817 - cysteine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006423 - cysteinyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1314208

TR61B
tRNA

3

1

High-throughput

0.667

High

1086795

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

1

Small-scale

0.640

High

1124807

OXLD1
Oxidoreductase-like domain-containing protein 1

3

0

High-throughput

0.638

High

1331836

RGCC
Regulator of cell cycle RGCC

3

0

High-throughput

0.638

High

228740

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

262974

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.584

High

1018062

GRSF1
G-rich sequence factor 1

2

1

High-throughput

0.584

High

1326156

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

5

High-throughput

0.563

High

427925

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.513

High

1328175

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.513

High

891327

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

5

High-throughput

0.501

High

1330851

Q9H4D1
Protein kinase

1

1

High-throughput

0.481

High

63455

MET15
12S rRNA N4-methylcytidine

1

1

High-throughput

0.479

High

265042

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.479

High

270126

RF1M
Peptide chain release factor 1, mitochondrial

1

5

High-throughput

0.479

High

327569

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

338997

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

440742

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

486643

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

497610

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.479

High

500128

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

652292

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

737494

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

777747

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

790005

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

799367

EFTS
Elongation factor Ts, mitochondrial

1

1

High-throughput

0.479

High

803238

IF2M
Translation initiation factor IF-2, mitochondrial

1

6

High-throughput

0.479

High

815294

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.479

High

827599

EFTU
Elongation factor Tu, mitochondrial

1

9

High-throughput

0.479

High

959054

TFAM
Transcription factor A, mitochondrial

1

2

High-throughput

0.479

High

981432

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

990317

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1014507

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

1020569

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

1045867

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

1051097

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.479

High

1068088

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

1128257

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1152973

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1157981

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

2

High-throughput

0.479

High

1171767

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1184043

DHX30
ATP-dependent RNA helicase DHX30

1

1

High-throughput

0.479

High

1185375

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

6

High-throughput

0.479

High

1219011

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.479

High

1282841

FAKD4
FAST kinase domain-containing protein 4

1

6

High-throughput

0.479

High

1284528

MCUR1
Mitochondrial calcium uniporter regulator 1

1

2

High-throughput

0.479

High

1288998

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.479

High

1289134

MTEF3
Transcription termination factor 3, mitochondrial

1

1

High-throughput

0.479

High

1301148

EFGM
Elongation factor G, mitochondrial

1

6

High-throughput

0.479

High

1311182

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1312715

TMM70
Transmembrane protein 70, mitochondrial

1

1

High-throughput

0.479

High

1317131

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.479

High

1326520

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1329480

IF3M
Translation initiation factor IF-3, mitochondrial

1

1

High-throughput

0.479

High

1330094

MTRFR
Mitochondrial translation release factor in rescue

1

5

High-throughput

0.479

High

1331124

MTG2
Mitochondrial ribosome-associated GTPase 2

1

3

High-throughput

0.479

High

1331324

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1333358

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

1

High-throughput

0.479

High

1334652

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

3

High-throughput

0.479

High

1334653

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

2

High-throughput

0.479

High

1334654

AKIP
Small ribosomal subunit protein mS38

1

1

High-throughput

0.479

High

1334655

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

6

High-throughput

0.479

High

1334656

MRES1
Mitochondrial transcription rescue factor 1

1

1

High-throughput

0.479

High

1334657

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

5

High-throughput

0.479

High

1334658

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1334660

RM11
Large ribosomal subunit protein uL11m

1

1

High-throughput

0.479

High

1201066

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.470

High

214377

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

274636

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

1183701

TM10C
tRNA methyltransferase 10 homolog C

1

0

Small-scale

0.458

High

1334651

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.458

High

175216

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.457

High

306325

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

5

High-throughput

0.457

High

1328035

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

5

High-throughput

0.457

High

1330630

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

5

High-throughput

0.457

High

883646

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.457

High

1295238

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

173119

RT12
Small ribosomal subunit protein uS12m

1

2

High-throughput

0.437

High

553753

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

721483

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

951350

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.437

High

1064734

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.437

High

1158862

CH082
UPF0598 protein C8orf82

1

1

High-throughput

0.437

High

1302846

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.437

High

1311325

CQ080
Mitochondrial nucleoid-associated protein 1

1

1

High-throughput

0.437

High

1333089

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.437

High

1334650

BIRC6
Baculoviral IAP repeat-containing protein 6

1

3

Small-scale

0.437

High

203046

COCH
Cochlin

1

0

High-throughput

0.279

Low

1166412

LYPD2
Ly6/PLAUR domain-containing protein 2

1

0

High-throughput

0.279

Low

1334659

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.279

Low

671926

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024