Protein: SC61G
Protein transport protein Sec61 subunit gamma

Gene: SC61G, SEC61G
Organism: Homo sapiens
Interactions: 40
UniProt ID: P60059

Gene Ontology (top 5):
GO:0005784 - Sec61 translocon complex
GO:0005829 - cytosol
GO:0008320 - protein transmembrane transporter activity
GO:0016020 - membrane
GO:0031204 - post-translational protein targeting to membrane, translocation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

948995

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.691

High

948996

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

2

Small-scale

0.647

High

949016

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

1

High-throughput

0.606

High

142090

PEX12
Peroxisome assembly protein 12

2

0

High-throughput

0.580

High

949010

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.580

High

949019

TMM51
Transmembrane protein 51

2

0

High-throughput

0.580

High

479358

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

698539

CALX
Calnexin

1

0

High-throughput

0.513

High

859167

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

884009

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

948997

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

948998

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

949002

ILF3
Interleukin enhancer-binding factor 3

1

0

High-throughput

0.513

High

949006

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

949015

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

949020

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

949021

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

230294

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.508

High

949018

RBM42
RNA-binding protein 42

1

1

High-throughput

0.489

High

949022

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

170036

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

948999

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

949001

ANK2
Ankyrin-2

1

0

High-throughput

0.458

High

949003

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

949007

MK14
Mitogen-activated protein kinase 14

1

0

High-throughput

0.458

High

949011

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

949017

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

949009

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

949000

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.316

High

949004

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

949008

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

547992

PSPC
Surfactant protein C

1

0

High-throughput

0.299

High

542407

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.279

Low

949005

RBM39
RNA-binding protein 39

1

0

High-throughput

0.279

Low

949013

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.279

Low

588341

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695071

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

767830

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

949012

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

949014

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025