Protein: CLNK
Cytokine-dependent hematopoietic cell linker (Mast cell immunoreceptor signal transducer)

Gene: CLNK
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q7Z7G1

Gene Ontology (top 5):
GO:0002729 - positive regulation of natural killer cell cytokine production
GO:0005737 - cytoplasm
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0032815 - negative regulation of natural killer cell activation
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

156049

SOCS6
Suppressor of cytokine signaling 6

2

20

High-throughput

0.767

High

699790

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

High-throughput

0.767

High

840917

TXK
Tyrosine-protein kinase TXK

2

20

High-throughput

0.743

High

855670

CRK
Adapter molecule crk

2

20

High-throughput

0.743

High

908212

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

20

High-throughput

0.743

High

987739

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.743

High

1281165

RASF1
Ras association domain-containing protein 1

2

6

High-throughput

0.743

High

1101746

PTK7
Inactive tyrosine-protein kinase 7

2

20

High-throughput

0.686

High

1281162

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.686

High

363503

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

410922

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

143864

NDKM
Nucleoside diphosphate kinase, mitochondrial

2

2

High-throughput

0.594

High

1148856

PP1R7
Protein phosphatase 1 regulatory subunit 7

2

1

High-throughput

0.594

High

442756

RB
Retinoblastoma-associated protein

2

1

High-throughput

0.576

High

1281164

STK36
Serine/threonine-protein kinase 36

2

4

High-throughput

0.576

High

1281166

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.576

High

1281168

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

2

2

High-throughput

0.576

High

1281157

RIP
RPA-interacting protein

2

0

High-throughput

0.569

High

1281160

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.551

High

1281167

SMBT1
Scm-like with four MBT domains protein 1

2

1

High-throughput

0.542

High

1281161

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

16

High-throughput

0.481

High

951730

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

156559

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.310

High

275051

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

0

High-throughput

0.310

High

1281158

F217A
Protein FAM217A

2

0

High-throughput

0.310

High

1281159

GLIS3
Zinc finger protein GLIS3

2

0

High-throughput

0.310

High

191355

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

2

0

High-throughput

0.300

High

1281163

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.300

High

1281169

ANR50
Ankyrin repeat domain-containing protein 50

2

0

High-throughput

0.300

High


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Last updated: 11Aug2025