Protein: EST2
Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) (Methylumbelliferyl-acetate deacetylase 2) (EC 3.1.1.56)

Gene: EST2, CES2
Organism: Homo sapiens
Interactions: 28
UniProt ID: O00748

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006693 - prostaglandin metabolic process
GO:0006805 - xenobiotic metabolic process
GO:0009056 - catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

143957

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.628

High

143962

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.513

High

143963

CIP4
Cdc42-interacting protein 4

1

0

High-throughput

0.513

High

143966

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.513

High

143964

PKN2
Serine/threonine-protein kinase N2

1

1

High-throughput

0.489

High

143968

ARHG1
Rho guanine nucleotide exchange factor 1

1

4

High-throughput

0.489

High

143970

CREL1
Protein disulfide isomerase CRELD1

1

5

High-throughput

0.489

High

143978

SNTG1
Gamma-1-syntrophin

1

20

High-throughput

0.489

High

143979

STK26
Serine/threonine-protein kinase 26

1

3

High-throughput

0.489

High

143981

STK24
Serine/threonine-protein kinase 24

1

3

High-throughput

0.489

High

143980

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

143960

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.426

High

143954

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

High-throughput

0.279

Low

143955

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.279

Low

143958

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.279

Low

143959

A2AP
Alpha-2-antiplasmin

1

0

High-throughput

0.279

Low

143961

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

143965

PNM8A
Paraneoplastic antigen-like protein 8A

1

0

High-throughput

0.279

Low

143967

KLDC4
Kelch domain-containing protein 4

1

0

High-throughput

0.279

Low

143969

ANKR9
Ankyrin repeat domain-containing protein 9

1

0

High-throughput

0.279

Low

143971

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

143972

SCYL1
N-terminal kinase-like protein

1

0

High-throughput

0.279

Low

143973

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

143974

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.279

Low

143975

RTF2
Replication termination factor 2

1

0

High-throughput

0.279

Low

143976

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.279

Low

143977

CHM1A
Charged multivesicular body protein 1a

1

0

High-throughput

0.279

Low

143956

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025