Protein: P4K2A
Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha)

Gene: P4K2A, PI4K2A
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q9BTU6

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000287 - magnesium ion binding
GO:0004430 - 1-phosphatidylinositol 4-kinase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902036

RAB9A
Ras-related protein Rab-9A

2

1

High-throughput

0.789

High

580826

PVR
Poliovirus receptor

2

0

High-throughput

0.770

High

252714

TSN3
Tetraspanin-3

3

0

High-throughput

0.638

High

1413675

PACC1
Proton-activated chloride channel

3

0

High-throughput

0.634

High

328137

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

1

High-throughput

0.628

High

466438

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.618

High

601425

RHOQ
Rho-related GTP-binding protein RhoQ

1

5

High-throughput

0.618

High

901530

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.618

High

953643

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.618

High

955534

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.618

High

978261

RHOB
Rho-related GTP-binding protein RhoB

1

6

High-throughput

0.618

High

988663

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

High-throughput

0.618

High

1270968

RHOU
Rho-related GTP-binding protein RhoU

1

6

High-throughput

0.618

High

1387024

HAVR1
Hepatitis A virus cellular receptor 1

1

1

Small-scale

0.618

High

374887

RASH
GTPase HRas

1

0

Small-scale

0.614

High

1228775

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

2

0

High-throughput

0.602

High

1239410

IIGP5
Interferon-inducible GTPase 5

2

0

High-throughput

0.602

High

190474

COPT1
High affinity copper uptake protein 1

2

1

High-throughput

0.601

High

483846

CD7
T-cell antigen CD7

1

0

Small-scale

0.586

High

1394600

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

2

Small-scale

0.561

High

178377

NPC1
NPC intracellular cholesterol transporter 1

2

0

High-throughput

0.547

High

166029

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.536

High

220515

RNF13
E3 ubiquitin-protein ligase RNF13

1

1

High-throughput

0.536

High

540649

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.536

High

790176

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

1

High-throughput

0.536

High

1256354

AN13D
Ankyrin repeat domain-containing protein 13D

1

1

High-throughput

0.536

High

1315839

AN13A
Ankyrin repeat domain-containing protein 13A

1

1

High-throughput

0.536

High

1413671

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.536

High

1413673

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.536

High

713130

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.518

High

931588

RD23A
UV excision repair protein RAD23 homolog A

1

0

High-throughput

0.518

High

64103

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.513

High

127724

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.513

High

376638

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

482634

GNAO
Guanine nucleotide-binding protein G(o) subunit alpha

1

0

High-throughput

0.513

High

720030

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.513

High

733426

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

904239

P2RX1
P2X purinoceptor 1

1

0

High-throughput

0.513

High

940570

AP1S2
AP-1 complex subunit sigma-2

1

0

High-throughput

0.513

High

1154726

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1330633

CCYL1
Cyclin-Y-like protein 1

1

0

High-throughput

0.513

High

1340740

TPC2
Two pore channel protein 2

1

0

High-throughput

0.513

High

1413667

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.513

High

1413676

FANCE
Fanconi anemia group E protein

1

0

High-throughput

0.513

High

1413677

TRXR2
Thioredoxin reductase 2, mitochondrial

1

0

High-throughput

0.513

High

1413686

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.513

High

358897

AL1A1
Aldehyde dehydrogenase 1A1

1

0

High-throughput

0.493

High

1413684

PHF8
Histone lysine demethylase PHF8

1

1

High-throughput

0.489

High

423032

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.481

High

185975

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

242766

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

461881

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.479

High

508539

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

562363

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

1334535

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

1413672

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

2

Small-scale

0.479

High

1413683

TTC7A
Tetratricopeptide repeat protein 7A

1

1

Small-scale

0.479

High

1410298

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.460

High

560500

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

1045712

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1063580

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.458

High

1314539

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

1413680

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1413681

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

0

High-throughput

0.458

High

1413685

RBGP1
Rab GTPase-activating protein 1

1

0

High-throughput

0.458

High

259078

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.445

High

943541

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

1

High-throughput

0.445

High

1131604

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.445

High

1277283

S46A3
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3

1

4

High-throughput

0.445

High

1316219

S22AF
Solute carrier family 22 member 15

1

1

High-throughput

0.445

High

1340558

MFSD8
Major facilitator superfamily domain-containing protein 8

1

2

High-throughput

0.445

High

1397970

MF14A
Hippocampus abundant transcript 1 protein

1

4

High-throughput

0.445

High

1413670

S46A2
Solute carrier family 46 member 2

1

4

High-throughput

0.445

High

1413682

XPO7
Exportin-7

1

1

High-throughput

0.437

High

653541

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1236295

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1238892

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

1334280

S38A9
Neutral amino acid transporter 9

1

0

High-throughput

0.426

High

1413669

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.426

High

1413679

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

0

High-throughput

0.426

High

1352569

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

1

High-throughput

0.407

High

1413674

TM231
Transmembrane protein 231

3

0

High-throughput

0.347

High

143974

EST2
Cocaine esterase

1

0

High-throughput

0.279

Low

1159413

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1352358

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

1413678

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

1255312

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1384073

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.249

Low

1413668

SYCP2
Synaptonemal complex protein 2

1

0

High-throughput

0.249

Low

330296

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025