Protein: RTF2
Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1)

Gene: RTF2
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9BY42

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005657 - replication fork
GO:0072711 - cellular response to hydroxyurea
GO:0097752 - regulation of DNA stability

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1340155

KDM2B
Lysine-specific demethylase 2B

1

1

High-throughput

0.536

High

322679

KDM4B
Lysine-specific demethylase 4B

1

0

High-throughput

0.513

High

336236

ZIC2
Zinc finger protein ZIC 2

1

0

High-throughput

0.513

High

894140

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.513

High

1143861

TCAL1
Transcription elongation factor A protein-like 1

1

0

High-throughput

0.513

High

1293409

CARM1
Histone-arginine methyltransferase CARM1

1

0

High-throughput

0.513

High

1392884

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.513

High

1416353

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.513

High

1417733

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

996010

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

1

High-throughput

0.501

High

185988

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.493

High

278151

FLNB
Filamin-B

1

1

High-throughput

0.489

High

1125391

FLNC
Filamin-C

1

1

High-throughput

0.489

High

1417735

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

2

High-throughput

0.489

High

1417738

KDM2A
Lysine-specific demethylase 2A

1

1

High-throughput

0.489

High

221178

SPY2
Protein sprouty homolog 2

1

0

High-throughput

0.486

High

508561

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

982304

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

0

High-throughput

0.480

High

714403

PML
Protein PML

1

1

High-throughput

0.479

High

971030

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

1100337

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

242815

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

260407

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

347914

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

349231

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

373061

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

887197

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

998768

H31
Histone H3.1

1

0

High-throughput

0.458

High

1025418

CDK6
Cyclin-dependent kinase 6

1

0

High-throughput

0.458

High

1067685

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1138599

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1241779

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1313402

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1326220

PNKD
Probable thioesterase PNKD

1

0

High-throughput

0.458

High

1356071

DDI1
Protein DDI1 homolog 1

1

0

Small-scale

0.458

High

1364241

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1367188

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1417734

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1417737

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

109158

G4U4J3
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.437

High

1227394

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1336629

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.437

High

1130432

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1198653

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

298270

BODG
Gamma-butyrobetaine dioxygenase

3

0

High-throughput

0.347

High

191975

TEX28
Testis-specific protein TEX28

2

0

High-throughput

0.328

High

1251683

T184A
Transmembrane protein 184A

2

0

High-throughput

0.328

High

771084

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

0

High-throughput

0.282

High

143975

EST2
Cocaine esterase

1

0

High-throughput

0.279

Low

320840

KLH18
Kelch-like protein 18

1

0

High-throughput

0.279

Low

355102

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

0

High-throughput

0.279

Low

699577

IL1R2
Interleukin-1 receptor type 2

1

0

High-throughput

0.279

Low

1208954

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.279

Low

1211103

TMM69
Transmembrane protein 69

1

0

High-throughput

0.279

Low

1247725

RSLBA
Ras-like protein family member 11A

1

0

High-throughput

0.279

Low

1280220

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

1328938

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.279

Low

1339337

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.279

Low

1366809

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

0

High-throughput

0.279

Low

1389108

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

181017

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

1

0

High-throughput

0.249

Low

346707

NDST3
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

1

0

High-throughput

0.249

Low

1255390

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1417732

TOLIP
Toll-interacting protein

1

0

High-throughput

0.249

Low

1417736

WRP73
WD repeat-containing protein WRAP73

1

0

High-throughput

0.249

Low

1417739

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1234938

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025