Protein: RCK1
Serine/threonine-protein kinase RCK1 (EC 2.7.11.1)

Gene: RCK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 178
UniProt ID: P38622

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

737841

HOG1
Mitogen-activated protein kinase HOG1

2

19

High-throughput

0.806

High

599352

FUS3
Mitogen-activated protein kinase FUS3

2

17

High-throughput

0.789

High

448707

SNF1
Carbon catabolite-derepressing protein kinase

1

17

High-throughput

0.691

High

548691

RNA1
Ran GTPase-activating protein 1

1

4

High-throughput

0.647

High

675967

MAS5
Mitochondrial protein import protein MAS5

1

10

High-throughput

0.647

High

752002

PACC
pH-response transcription factor pacC/RIM101

1

3

High-throughput

0.647

High

763224

PP2C1
Protein phosphatase 2C homolog 1

1

14

High-throughput

0.647

High

800707

ARB1
ABC transporter ATP-binding protein ARB1

1

3

High-throughput

0.647

High

800755

PDR12
ATP-dependent permease PDR12

1

2

Small-scale

0.621

High

602434

PHO85
Cyclin-dependent protein kinase PHO85

1

10

High-throughput

0.618

High

709368

HRR25
Casein kinase I homolog HRR25

1

17

High-throughput

0.618

High

800703

SSN3
Meiotic mRNA stability protein kinase SSN3

1

16

High-throughput

0.618

High

800748

ARP4
Actin-related protein 4

1

7

High-throughput

0.618

High

800720

BIR1
Chromosomal passenger complex protein BIR1

1

0

High-throughput

0.614

High

800743

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

10

High-throughput

0.602

High

619424

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.586

High

800697

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.586

High

779606

VPS21
Vacuolar protein sorting-associated protein 21

1

5

High-throughput

0.579

High

800765

RRP5
rRNA biogenesis protein RRP5

1

5

High-throughput

0.579

High

579311

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.575

High

800781

GIN4
Serine/threonine-protein kinase GIN4

1

20

High-throughput

0.575

High

800750

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

13

Small-scale

0.552

High

673500

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

2

3

Small-scale

0.543

High

557008

AAKG
5'-AMP-activated protein kinase subunit gamma

1

9

High-throughput

0.536

High

666657

AP2
AP-1-like transcription factor YAP2

1

0

Small-scale

0.529

High

800718

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.514

High

416116

SYTC
Threonine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

594348

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.501

High

636569

PSA7
Probable proteasome subunit alpha type-7

1

3

High-throughput

0.501

High

670259

NAP1
Nucleosome assembly protein

1

2

High-throughput

0.501

High

745441

KU70
ATP-dependent DNA helicase II subunit 1

1

3

High-throughput

0.501

High

746620

DRS1
ATP-dependent RNA helicase DRS1

1

11

High-throughput

0.501

High

750236

PRP40
Pre-mRNA-processing protein PRP40

1

2

High-throughput

0.501

High

800694

GRE3
NADPH-dependent aldose reductase GRE3

1

1

High-throughput

0.501

High

800706

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

7

High-throughput

0.501

High

800713

SYA
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.501

High

800715

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

1

High-throughput

0.501

High

800719

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.501

High

800722

YJ66
Uncharacterized oxidoreductase YJR096W

1

1

High-throughput

0.501

High

800725

JHD2
Histone demethylase JHD2

1

2

High-throughput

0.501

High

800741

REXO1
RNA exonuclease 1

1

1

High-throughput

0.501

High

800769

BDF2
Bromodomain-containing factor 2

1

5

High-throughput

0.501

High

800778

SAS10
Something about silencing protein 10

1

1

High-throughput

0.501

High

800788

NOT5
General negative regulator of transcription subunit 5

1

1

High-throughput

0.501

High

359005

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

6

High-throughput

0.500

High

599009

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

5

High-throughput

0.500

High

607755

HXKG
Glucokinase-1

1

4

High-throughput

0.500

High

679629

CDC48
Cell division control protein 48

1

3

High-throughput

0.500

High

800756

ROD1
Protein ROD1

1

3

High-throughput

0.489

High

800774

RPN8
26S proteasome regulatory subunit RPN8

1

3

High-throughput

0.489

High

800721

BUD4
Bud site selection protein 4

1

0

High-throughput

0.481

High

365610

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.480

High

642176

OPI1
Transcriptional repressor OPI1

1

0

High-throughput

0.480

High

645050

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.480

High

748285

SPT4
Transcription elongation factor SPT4

1

0

High-throughput

0.480

High

795971

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

0

High-throughput

0.480

High

800700

ADY1
Prospore formation at selected spindle poles protein 1

1

0

High-throughput

0.480

High

800709

VID27
Vacuolar import and degradation protein 27

1

0

High-throughput

0.480

High

800723

ADK
Adenosine kinase

1

0

High-throughput

0.480

High

800726

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.480

High

800734

DXO
Decapping nuclease RAI1

1

0

High-throughput

0.480

High

800738

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.480

High

800753

RNT1
Ribonuclease 3

1

0

High-throughput

0.480

High

800760

EKI1
Ethanolamine kinase

1

0

High-throughput

0.480

High

800786

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.480

High

459081

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.479

High

614820

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

10

High-throughput

0.479

High

643634

SNF2
Transcription regulatory protein SNF2

1

2

High-throughput

0.479

High

644918

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.479

High

738150

NGG1
SAGA complex subunit NGG1

1

1

High-throughput

0.479

High

743021

SWI3
SWI/SNF complex subunit SWI3

1

3

High-throughput

0.479

High

762813

TOR1
Serine/threonine-protein kinase TOR1

1

18

High-throughput

0.479

High

762951

SPT7
SAGA complex subunit SPT7

1

9

High-throughput

0.479

High

793912

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

4

High-throughput

0.479

High

800699

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

17

High-throughput

0.479

High

800731

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

5

High-throughput

0.479

High

800732

SPT20
SAGA complex subunit SPT20

1

1

High-throughput

0.479

High

800747

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.479

High

800751

ADA2
SAGA complex subunit ADA2

1

3

High-throughput

0.479

High

800757

GCN5
Histone acetyltransferase GCN5

1

9

High-throughput

0.479

High

800759

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

1

High-throughput

0.479

High

800777

HFI1
SAGA complex subunit HFI1

1

1

High-throughput

0.479

High

800780

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

449455

SPT3
SAGA complex subunit SPT3

1

0

High-throughput

0.458

High

483777

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.458

High

617790

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.458

High

624906

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.458

High

676635

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.458

High

733537

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.458

High

740400

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.458

High

800692

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.458

High

800701

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.458

High

800716

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

0

High-throughput

0.458

High

800717

EPL1
Enhancer of polycomb-like protein 1

1

0

High-throughput

0.458

High

800728

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.458

High

800733

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.458

High

800736

MED5
Mediator of RNA polymerase II transcription subunit 5

1

0

High-throughput

0.458

High

800737

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.458

High

800742

SNF12
Transcription regulatory protein SNF12

1

0

High-throughput

0.458

High

800745

AF9
Protein AF-9 homolog

1

0

High-throughput

0.458

High

800754

RPM2
Ribonuclease P protein component, mitochondrial

1

0

High-throughput

0.458

High

800767

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.458

High

800768

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.458

High

800776

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

0

High-throughput

0.458

High

800782

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.458

High

800784

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

438813

CYSD
Homocysteine/cysteine synthase

1

3

High-throughput

0.457

High

446224

PHSG
Glycogen phosphorylase

1

3

High-throughput

0.457

High

511407

RL43B
Large ribosomal subunit protein eL43B

1

3

High-throughput

0.457

High

582241

AMPD
AMP deaminase

1

1

High-throughput

0.457

High

600682

SEC2
Rab guanine nucleotide exchange factor SEC2

1

2

High-throughput

0.457

High

668426

PTP1
Tyrosine-protein phosphatase 1

1

7

High-throughput

0.457

High

725721

RM09
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.457

High

751150

SFC1
Succinate/fumarate mitochondrial transporter

1

5

High-throughput

0.457

High

800695

OSH7
Oxysterol-binding protein homolog 7

1

1

High-throughput

0.457

High

800696

DOG1
2-deoxyglucose-6-phosphate phosphatase 1

1

1

High-throughput

0.457

High

800710

MMF1
Protein MMF1, mitochondrial

1

1

High-throughput

0.457

High

800712

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.457

High

800730

HSV2
SVP1-like protein 2

1

9

High-throughput

0.457

High

800762

YHM2
Citrate/oxoglutarate carrier protein

1

5

High-throughput

0.457

High

800764

GSF2
Glucose-signaling factor 2

1

1

High-throughput

0.457

High

800775

FSF1
Sideroflexin FSF1

1

2

High-throughput

0.457

High

800787

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

1

High-throughput

0.457

High

359471

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

6

High-throughput

0.457

High

367746

ENO1
Enolase 1

1

4

High-throughput

0.457

High

368653

PMG1
Phosphoglycerate mutase 1

1

8

High-throughput

0.457

High

405083

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.457

High

800783

HSP42
Heat shock protein 42

1

1

High-throughput

0.457

High

510453

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.445

High

526575

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

544709

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

800698

SSZ1
Ribosome-associated complex subunit SSZ1

1

10

High-throughput

0.445

High

800708

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

800711

ATAD2
ATPase histone chaperone YTA7

1

5

High-throughput

0.445

High

800739

ENV11
Late endosome and vacuole interface protein 11

1

1

High-throughput

0.445

High

800766

VID22
Vacuolar import and degradation protein 22

1

1

High-throughput

0.445

High

628259

ZRC1
Vacuolar zinc transporter ZRC1

1

1

Small-scale

0.439

High

746702

TRS65
Trafficking protein particle complex II-specific subunit 65

1

1

Small-scale

0.439

High

800746

AQR1
Probable transporter AQR1

1

5

Small-scale

0.439

High

737714

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

5

High-throughput

0.437

High

575279

RAD9
DNA repair protein RAD9

1

0

High-throughput

0.426

High

800752

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

672237

CDC10
Cell division control protein 10

1

3

High-throughput

0.407

High

737082

CDC11
Cell division control protein 11

1

4

High-throughput

0.407

High

737308

CDC12
Cell division control protein 12

1

1

High-throughput

0.407

High

800740

YG3A
Uncharacterized protein YGR130C

1

13

High-throughput

0.407

High

800749

NUM1
Nuclear migration protein NUM1

1

16

High-throughput

0.407

High

800770

SHS1
Seventh homolog of septin 1

1

5

High-throughput

0.407

High

701518

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

0

High-throughput

0.279

Low

506416

PAU8
Seripauperin-8

1

0

High-throughput

0.261

Low

652920

BET1
Protein transport protein BET1

1

0

High-throughput

0.261

Low

654601

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.261

Low

723605

MLS1
Malate synthase 1

1

0

High-throughput

0.261

Low

745157

CACP
Carnitine O-acetyltransferase, mitochondrial

1

0

High-throughput

0.261

Low

745180

CDC13
Cell division control protein 13

1

0

High-throughput

0.261

Low

795798

SHE1
Mitotic spindle-associated protein SHE1

1

0

High-throughput

0.261

Low

800693

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.261

Low

800704

ERV46
ER-derived vesicles protein ERV46

1

0

High-throughput

0.261

Low

800714

YG4I
Uncharacterized GTP-binding protein YGR210C

1

0

High-throughput

0.261

Low

800724

YJ85
Uncharacterized protein YJR115W

1

0

High-throughput

0.261

Low

800727

YJ9J
Uncharacterized protein YJR142W

1

0

High-throughput

0.261

Low

800729

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.261

Low

800735

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.261

Low

800758

YMD7
Uncharacterized protein YML037C

1

0

High-throughput

0.261

Low

800761

YM30
Uncharacterized membrane protein YMR155W

1

0

High-throughput

0.261

Low

800763

MGR3
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3

1

0

High-throughput

0.261

Low

800771

NBA1
Protein NBA1

1

0

High-throughput

0.261

Low

800772

IRC23
Increased recombination centers protein 23

1

0

High-throughput

0.261

Low

800773

PEX27
Peroxisomal membrane protein PEX27

1

0

High-throughput

0.261

Low

800779

YP063
Uncharacterized protein YPR063C

1

0

High-throughput

0.261

Low

800785

JLP1
Alpha-ketoglutarate-dependent sulfonate dioxygenase

1

0

High-throughput

0.261

Low

678807

SRB8
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.249

Low

800702

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.249

Low

800705

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.249

Low

676801

BUD3
Bud site selection protein 3

1

0

High-throughput

0.232

Low

736965

CDC3
Cell division control protein 3

1

0

High-throughput

0.232

Low

763529

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.232

Low

800744

BNI5
Bud neck protein 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025