Protein: TPK1
Thiamine pyrophosphokinase 1 (hTPK1) (EC 2.7.6.-) (Placental protein 20) (PP20) (Thiamin pyrophosphokinase 1)

Gene: TPK1
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q9H3S4

Gene Ontology (top 5):
GO:0004788 - thiamine diphosphokinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006772 - thiamine metabolic process
GO:0009229 - thiamine diphosphate biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432885

TPK1
Thiamine pyrophosphokinase 1

5

2

Small-scale

0.918

High

165850

OPLA
5-oxoprolinase

2

0

High-throughput

0.580

High

697429

DCK
Deoxycytidine kinase

1

0

High-throughput

0.513

High

951853

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.513

High

1201230

SPIN4
Spindlin-4

1

0

High-throughput

0.513

High

1324411

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

0

High-throughput

0.513

High

1432886

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1432888

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.513

High

857175

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.493

High

1129125

PLSI
Plastin-1

1

0

High-throughput

0.493

High

404413

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

1432889

PARP2
Poly [ADP-ribose] polymerase 2

1

0

Small-scale

0.426

High

1178674

ISX
Intestine-specific homeobox

1

0

High-throughput

0.279

Low

1185946

PCGF3
Polycomb group RING finger protein 3

1

0

High-throughput

0.279

Low

1211105

TMM69
Transmembrane protein 69

1

0

High-throughput

0.279

Low

1247726

RSLBA
Ras-like protein family member 11A

1

0

High-throughput

0.279

Low

1277406

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.279

Low

1315248

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.279

Low

1327384

ZCHC9
Zinc finger CCHC domain-containing protein 9

1

0

High-throughput

0.279

Low

1384067

TMM18
Transmembrane protein 18

1

0

High-throughput

0.279

Low

1412276

RHNO1
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1

1

0

High-throughput

0.279

Low

1432887

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1432890

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025