Protein: DCK
Deoxycytidine kinase (dCK) (EC 2.7.1.74) (Deoxyadenosine kinase) (EC 2.7.1.76) (Deoxyguanosine kinase) (EC 2.7.1.113)

Gene: DCK
Organism: Homo sapiens
Interactions: 53
UniProt ID: P27707

Gene Ontology (top 5):
GO:0004136 - deoxyadenosine kinase activity
GO:0004137 - deoxycytidine kinase activity
GO:0004138 - deoxyguanosine kinase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

697415

DGUOK
Deoxyguanosine kinase, mitochondrial

4

3

High-throughput

0.892

High

697402

DCK
Deoxycytidine kinase

1

3

High-throughput

0.656

High

697428

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

2

0

High-throughput

0.576

High

664029

PRTN3
Myeloblastin

1

2

High-throughput

0.536

High

48911

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.518

High

168935

TFEC
Transcription factor EC

1

0

High-throughput

0.518

High

697434

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.518

High

697421

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.513

High

697429

TPK1
Thiamine pyrophosphokinase 1

1

0

High-throughput

0.513

High

697430

PKHG2
Pleckstrin homology domain-containing family G member 2

1

0

High-throughput

0.513

High

697431

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

697433

DACH1
Dachshund homolog 1

1

0

High-throughput

0.513

High

182470

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

634744

GRAH
Granzyme H

1

1

High-throughput

0.489

High

697419

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

1

High-throughput

0.489

High

697406

RXRG
Retinoic acid receptor RXR-gamma

1

0

High-throughput

0.486

High

384369

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

697414

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.480

High

697405

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

1

High-throughput

0.479

High

697407

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.479

High

697408

KC1D
Casein kinase I isoform delta

1

3

High-throughput

0.479

High

697409

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

697410

KC1E
Casein kinase I isoform epsilon

1

4

High-throughput

0.479

High

697422

KC1AL
Casein kinase I isoform alpha-like

1

3

High-throughput

0.479

High

293242

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

371226

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

411401

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

443197

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.458

High

461174

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

536551

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

697403

EF1D
Elongation factor 1-delta

1

0

Small-scale

0.458

High

697411

ICLN
Methylosome subunit pICln

1

0

Small-scale

0.458

High

697412

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

0

High-throughput

0.458

High

697418

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

697426

PHB2
Prohibitin-2

1

0

Small-scale

0.458

High

697427

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.458

High

697432

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

64853

RCCD1
RCC1 domain-containing protein 1

1

0

High-throughput

0.426

High

697420

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.426

High

697425

CHMP6
Charged multivesicular body protein 6

1

0

High-throughput

0.426

High

697435

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

697436

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.426

High

697413

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.407

High

697423

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.282

High

51308

NTM2F
NUT family member 2F

1

0

High-throughput

0.279

Low

455636

KLK3
Prostate-specific antigen

1

0

High-throughput

0.279

Low

539660

MBL2
Mannose-binding protein C

1

0

High-throughput

0.279

Low

697416

ISX
Intestine-specific homeobox

1

0

High-throughput

0.279

Low

697424

ZN503
Zinc finger protein 503

1

0

High-throughput

0.279

Low

697437

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

697404

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

697417

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025