Protein: PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]

Gene: PISD
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9UG56

Gene Ontology (top 5):
GO:0004609 - phosphatidylserine decarboxylase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1459150

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.580

High

1428935

PIP30
PSME3-interacting protein

2

0

High-throughput

0.576

High

1402108

IF140
Intraflagellar transport protein 140 homolog

1

1

High-throughput

0.536

High

564506

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

219390

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.513

High

259163

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.513

High

291873

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

521040

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

774689

BASI
Basigin

1

0

High-throughput

0.513

High

783675

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.513

High

1118626

TBB2A
Tubulin beta-2A chain

1

0

High-throughput

0.513

High

1310498

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1312902

ETKMT
Electron transfer flavoprotein beta subunit lysine methyltransferase

1

0

High-throughput

0.513

High

1324879

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1432888

TPK1
Thiamine pyrophosphokinase 1

1

0

High-throughput

0.513

High

1459156

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

86045

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

1

High-throughput

0.489

High

182817

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

380494

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

1

High-throughput

0.489

High

688641

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

1

High-throughput

0.489

High

1338256

WDR19
WD repeat-containing protein 19

1

1

High-throughput

0.489

High

1459154

PCDB7
Protocadherin beta-7

1

1

High-throughput

0.489

High

1459155

PCDB3
Protocadherin beta-3

1

1

High-throughput

0.489

High

508776

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1114563

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1115117

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1449216

KIF15
Kinesin-like protein KIF15

1

1

High-throughput

0.479

High

799547

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.460

High

129516

MEN1
Menin

1

0

High-throughput

0.458

High

611408

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

1095000

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.458

High

1095834

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

1178443

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1276915

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1367504

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1397527

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1435409

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1447391

ANLN
Anillin

1

0

High-throughput

0.458

High

1459149

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

786293

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.445

High

944093

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

1433464

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

273723

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

0

High-throughput

0.426

High

960599

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.426

High

1209762

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1251520

CD109
CD109 antigen

1

0

High-throughput

0.426

High

1311121

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.426

High

1405118

PLIN2
Perilipin-2

1

0

High-throughput

0.426

High

844979

EAA2
Excitatory amino acid transporter 2

1

1

High-throughput

0.407

High

845155

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.407

High

1278255

DHX29
ATP-dependent RNA helicase DHX29

1

0

High-throughput

0.282

High

1335577

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.282

High

260982

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

388675

C1QA
Complement C1q subcomponent subunit A

1

0

High-throughput

0.279

Low

957033

CXCR4
C-X-C chemokine receptor type 4

1

0

High-throughput

0.279

Low

1085958

HYAL1
Hyaluronidase-1

1

0

High-throughput

0.279

Low

1181557

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

0

High-throughput

0.279

Low

1213730

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1245935

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1287187

T150A
Transmembrane protein 150A

1

0

High-throughput

0.279

Low

1309005

S22A9
Organic anion transporter 7

1

0

High-throughput

0.279

Low

1325942

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1359100

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

1363246

AQP3
Aquaporin-3

1

0

High-throughput

0.279

Low

1420119

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.279

Low

1432882

TMPS5
Transmembrane protease serine 5

1

0

High-throughput

0.279

Low

1458511

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.279

Low

1459151

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.279

Low

1459153

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.279

Low

294481

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

377767

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1348239

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1197903

S39AC
Zinc transporter ZIP12

1

0

High-throughput

0.232

Low

1203524

S45A4
Solute carrier family 45 member 4

1

0

High-throughput

0.232

Low

1271282

SV2B
Synaptic vesicle glycoprotein 2B

1

0

High-throughput

0.232

Low

1459152

S12A4
Solute carrier family 12 member 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025