Protein: SHB
SH2 domain-containing adapter protein B

Gene: SHB
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q15464

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001784 - phosphotyrosine residue binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

209059

NCK2
Cytoplasmic protein NCK2

3

19

High-throughput

0.861

High

337483

ABL1
Tyrosine-protein kinase ABL1

1

19

Small-scale

0.747

High

508019

FGFR1
Fibroblast growth factor receptor 1

1

20

Small-scale

0.724

High

523000

SRC
Proto-oncogene tyrosine-protein kinase Src

1

19

Small-scale

0.724

High

548712

VAV
Proto-oncogene vav

1

20

Small-scale

0.724

High

655381

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.724

High

796472

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.724

High

1020367

EPS8
Epidermal growth factor receptor kinase substrate 8

1

20

Small-scale

0.724

High

1024133

LCP2
Lymphocyte cytosolic protein 2

1

20

Small-scale

0.724

High

441510

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

499269

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

729659

VGFR2
Vascular endothelial growth factor receptor 2

1

20

Small-scale

0.691

High

338468

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

383823

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

601926

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

616813

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.647

High

854182

JAK3
Tyrosine-protein kinase JAK3

1

20

Small-scale

0.647

High

1070967

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

433775

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

577024

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

20

High-throughput

0.618

High

581011

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

15

Small-scale

0.618

High

607978

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

665246

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

802608

CRK
Adapter molecule crk

1

20

Small-scale

0.618

High

924594

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

1072502

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.618

High

1074293

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.602

High

904593

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

600579

EPHA1
Ephrin type-A receptor 1

1

20

High-throughput

0.590

High

207448

LAT
Linker for activation of T-cells family member 1

2

6

Small-scale

0.584

High

350189

RASK
GTPase KRas

2

20

High-throughput

0.584

High

487462

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

1074290

FBLI1
Filamin-binding LIM protein 1

1

20

High-throughput

0.536

High

1074295

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

206373

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.518

High

540464

IL2RB
Interleukin-2 receptor subunit beta

1

20

Small-scale

0.516

High

179180

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

682264

IL2RG
Cytokine receptor common subunit gamma

1

20

Small-scale

0.501

High

661266

S10A2
Protein S100-A2

1

8

High-throughput

0.489

High

178545

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

212840

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

349338

RASH
GTPase HRas

1

20

High-throughput

0.479

High

507030

LAMP1
Lysosome-associated membrane glycoprotein 1

1

8

High-throughput

0.479

High

521950

CADH1
Cadherin-1

1

10

High-throughput

0.479

High

567068

CXA1
Gap junction alpha-1 protein

1

11

High-throughput

0.479

High

591855

RAB4A
Ras-related protein Rab-4A

1

10

High-throughput

0.479

High

592271

RAB5A
Ras-related protein Rab-5A

1

12

High-throughput

0.479

High

793322

MUC18
Cell surface glycoprotein MUC18

1

14

High-throughput

0.479

High

845497

RAB9A
Ras-related protein Rab-9A

1

13

High-throughput

0.479

High

876392

AFAD
Afadin

1

20

High-throughput

0.479

High

914085

RB11A
Ras-related protein Rab-11A

1

10

High-throughput

0.479

High

915695

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

925300

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

940429

CXAR
Coxsackievirus and adenovirus receptor

1

11

High-throughput

0.479

High

965686

IFM3
Interferon-induced transmembrane protein 3

1

7

High-throughput

0.479

High

974834

CAV1
Caveolin-1

1

8

High-throughput

0.479

High

1017640

STX4
Syntaxin-4

1

5

High-throughput

0.479

High

1041644

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1070203

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

1074285

OCLN
Occludin

1

2

High-throughput

0.479

High

1074286

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1074288

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

9

High-throughput

0.479

High

1074289

CXD3
Gap junction delta-3 protein

1

11

High-throughput

0.479

High

1074292

BICD1
Protein bicaudal D homolog 1

1

20

High-throughput

0.479

High

1074294

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1074296

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1074297

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.479

High

1074287

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.437

High

1074291

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024