Protein: MIB2
E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (RING-type E3 ubiquitin transferase MIB2) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1)

Gene: MIB2
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q96AX9

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003779 - actin binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005769 - early endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1284697

PD1L1
Programmed cell death 1 ligand 1

1

4

Small-scale

0.747

High

1284698

TBK1
Serine/threonine-protein kinase TBK1

1

6

High-throughput

0.734

High

330270

BCL10
B-cell lymphoma/leukemia 10

1

1

Small-scale

0.724

High

1076496

TRIP6
Thyroid receptor-interacting protein 6

1

9

High-throughput

0.691

High

1284696

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

18

High-throughput

0.691

High

181629

CFLAR
CASP8 and FADD-like apoptosis regulator

1

0

Small-scale

0.687

High

1284695

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

2

2

Small-scale

0.657

High

476162

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

High-throughput

0.647

High

849396

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

10

Small-scale

0.647

High

896510

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

10

High-throughput

0.647

High

919813

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

10

High-throughput

0.647

High

942855

SRPK2
SRSF protein kinase 2

1

4

High-throughput

0.647

High

352678

TNFA
Tumor necrosis factor

3

1

Small-scale

0.640

High

341284

FA9
Coagulation factor IX

2

1

High-throughput

0.628

High

814585

P2RY1
P2Y purinoceptor 1

2

1

High-throughput

0.628

High

1033703

IKZF1
DNA-binding protein Ikaros

2

2

High-throughput

0.628

High

1284692

IKZF5
Zinc finger protein Pegasus

2

3

High-throughput

0.628

High

1138900

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

8

High-throughput

0.625

High

894789

RAB8A
Ras-related protein Rab-8A

1

3

Small-scale

0.618

High

1284700

NEMO
NF-kappa-B essential modulator

1

11

Small-scale

0.618

High

1038299

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

20

Small-scale

0.611

High

1206016

MIB1
E3 ubiquitin-protein ligase MIB1

1

19

High-throughput

0.575

High

1028147

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

Small-scale

0.561

High

439082

ELNE
Neutrophil elastase

1

1

High-throughput

0.536

High

525010

XRCC5
X-ray repair cross-complementing protein 5

1

2

High-throughput

0.536

High

677161

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

1

High-throughput

0.536

High

821350

TCPE
T-complex protein 1 subunit epsilon

1

5

High-throughput

0.536

High

826811

TCPG
T-complex protein 1 subunit gamma

1

5

High-throughput

0.536

High

943398

TCPB
T-complex protein 1 subunit beta

1

9

High-throughput

0.536

High

995898

DEMA
Dematin

1

7

High-throughput

0.536

High

1017024

KCNH2
Potassium voltage-gated channel subfamily H member 2

1

5

High-throughput

0.536

High

1284689

TMM74
Transmembrane protein 74

1

2

High-throughput

0.536

High

1284690

TCPH
T-complex protein 1 subunit eta

1

5

High-throughput

0.536

High

1219212

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

20

High-throughput

0.533

High

933033

ACTS
Actin, alpha skeletal muscle

1

5

Small-scale

0.527

High

582424

NUCL
Nucleolin

1

4

High-throughput

0.515

High

739793

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

865157

PLAT3
Phospholipase A and acyltransferase 3

1

0

High-throughput

0.513

High

1187452

PLPR4
Phospholipid phosphatase-related protein type 4

1

0

High-throughput

0.513

High

1246398

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.513

High

1284699

JAG2
Protein jagged-2

1

20

Small-scale

0.501

High

1284688

LOXL4
Lysyl oxidase homolog 4

1

2

High-throughput

0.489

High

201390

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

8

Small-scale

0.479

High

1042234

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1190049

MAVS
Mitochondrial antiviral-signaling protein

1

9

Small-scale

0.479

High

1201344

SERC5
Serine incorporator 5

1

1

Small-scale

0.479

High

1242622

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

11

High-throughput

0.479

High

1284694

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

16

High-throughput

0.479

High

1168623

SYNE3
Nesprin-3

1

20

High-throughput

0.437

High

1172708

CE128
Centrosomal protein of 128 kDa

1

5

High-throughput

0.437

High

1284693

AZI2
5-azacytidine-induced protein 2

1

2

High-throughput

0.407

High

1284691

NUP58
Nucleoporin p58/p45

2

0

High-throughput

0.328

High

211394

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

592796

MCH
Pro-MCH [Cleaved into: Neuropeptide-glycine-glutamic acid

1

0

High-throughput

0.279

Low

1166369

CF015
Uncharacterized protein C6orf15

1

0

High-throughput

0.279

Low

1169005

MACC1
Metastasis-associated in colon cancer protein 1

1

0

High-throughput

0.279

Low

1235841

DB125
Beta-defensin 125

1

0

High-throughput

0.279

Low

1284687

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024