Protein: TMPSC
Transmembrane protease serine 12 (EC 3.4.21.-)

Gene: TMPSC, TMPRSS12
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q86WS5

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0001675 - acrosome assembly
GO:0004252 - serine-type endopeptidase activity
GO:0005886 - plasma membrane
GO:0007283 - spermatogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

247523

FZD6
Frizzled-6

2

3

High-throughput

0.628

High

791504

SYUA
Alpha-synuclein

2

3

High-throughput

0.628

High

1292692

ABCA3
Phospholipid-transporting ATPase ABCA3

2

2

High-throughput

0.628

High

1292697

POMT1
Protein O-mannosyl-transferase 1

2

4

High-throughput

0.628

High

1292528

AMGO1
Amphoterin-induced protein 1

1

16

High-throughput

0.618

High

1110799

PKD2
Polycystin-2

2

0

High-throughput

0.602

High

1292689

SIDT2
SID1 transmembrane family member 2

2

0

High-throughput

0.602

High

1292691

S47A1
Multidrug and toxin extrusion protein 1

2

0

High-throughput

0.602

High

773915

SOAT1
Sterol O-acyltransferase 1

2

1

High-throughput

0.574

High

1276010

D19L4
Probable C-mannosyltransferase DPY19L4

2

2

High-throughput

0.574

High

1292690

PIGB
GPI alpha-1,2-mannosyltransferase 3

2

7

High-throughput

0.574

High

1292695

ALG9
Alpha-1,2-mannosyltransferase ALG9

2

7

High-throughput

0.574

High

178316

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.536

High

354133

CLPT1
Putative lipid scramblase CLPTM1

1

1

High-throughput

0.536

High

984185

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.536

High

1125857

FZD2
Frizzled-2

1

3

High-throughput

0.536

High

1292693

VRK1
Serine/threonine-protein kinase VRK1

1

7

High-throughput

0.489

High

1292694

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

1292696

SNX6
Sorting nexin-6

1

4

High-throughput

0.489

High

799263

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.481

High

295844

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.279

Low

1254290

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025