Protein: CLPT1
Putative lipid scramblase CLPTM1 (Cleft lip and palate transmembrane protein 1)

Gene: CLPT1, CLPTM1
Organism: Homo sapiens
Interactions: 149
UniProt ID: O96005

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0012505 - endomembrane system
GO:0016020 - membrane
GO:0030154 - cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

354193

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

2

High-throughput

0.667

High

354100

SCNND
Epithelial sodium channel subunit delta

2

2

High-throughput

0.628

High

354161

ASIC4
Acid-sensing ion channel 4

2

2

High-throughput

0.628

High

354107

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.611

High

354097

5HT3A
5-hydroxytryptamine receptor 3A

2

0

High-throughput

0.602

High

354112

NTCP2
Ileal sodium/bile acid cotransporter

2

0

High-throughput

0.563

High

354095

CCR2
C-C chemokine receptor type 2

1

6

High-throughput

0.541

High

354101

CCR4
C-C chemokine receptor type 4

1

6

High-throughput

0.541

High

354105

PAR2
Proteinase-activated receptor 2

1

8

High-throughput

0.541

High

354072

CD1A
T-cell surface glycoprotein CD1a

1

3

High-throughput

0.536

High

354078

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

354083

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.536

High

354087

CALX
Calnexin

1

4

High-throughput

0.536

High

354088

S5A2
3-oxo-5-alpha-steroid 4-dehydrogenase 2

1

1

High-throughput

0.536

High

354089

CCR1
C-C chemokine receptor type 1

1

6

High-throughput

0.536

High

354094

P2RY2
P2Y purinoceptor 2

1

9

High-throughput

0.536

High

354102

CCR6
C-C chemokine receptor type 6

1

5

High-throughput

0.536

High

354109

ASIC1
Acid-sensing ion channel 1

1

2

High-throughput

0.536

High

354113

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

9

High-throughput

0.536

High

354133

TMPSC
Transmembrane protease serine 12

1

1

High-throughput

0.536

High

354146

SPP2B
Signal peptide peptidase-like 2B

1

2

High-throughput

0.536

High

354147

SPP
Signal peptide peptidase

1

2

High-throughput

0.536

High

354157

T106A
Transmembrane protein 106A

1

2

High-throughput

0.536

High

354158

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

354175

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.528

High

270421

FZD7
Frizzled-7

1

0

High-throughput

0.518

High

168358

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.513

High

214109

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

230690

NKG2F
NKG2-F type II integral membrane protein

1

0

High-throughput

0.513

High

354066

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.513

High

354073

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

354120

ODFP4
Outer dense fiber protein 4

1

0

High-throughput

0.513

High

354121

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.513

High

354128

NCEH1
Neutral cholesterol ester hydrolase 1

1

0

High-throughput

0.513

High

354131

TMC4
Voltage-gated chloride channel TMC4

1

0

High-throughput

0.513

High

354135

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.513

High

354138

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.513

High

354143

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

354149

T255B
Transmembrane protein 255B

1

0

High-throughput

0.513

High

354164

OR5MB
Olfactory receptor 5M11

1

0

High-throughput

0.513

High

354168

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.513

High

354172

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

354174

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.513

High

354181

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

354182

GP108
Protein GPR108

1

0

High-throughput

0.513

High

354186

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.513

High

354189

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.513

High

354194

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

170601

CLGN
Calmegin

1

4

High-throughput

0.489

High

354077

PSPC
Surfactant protein C

1

1

High-throughput

0.489

High

354134

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

354162

TECT2
Tectonic-2

1

2

High-throughput

0.489

High

354178

KLK15
Kallikrein-15

1

1

High-throughput

0.489

High

354187

DNJB9
DnaJ homolog subfamily B member 9

1

2

High-throughput

0.489

High

183901

S22A2
Solute carrier family 22 member 2

1

7

Small-scale

0.481

High

183996

S22A1
Solute carrier family 22 member 1

1

7

Small-scale

0.481

High

173824

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

3

High-throughput

0.479

High

178132

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

217676

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

354067

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

354069

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

354070

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.479

High

354076

FGFR1
Fibroblast growth factor receptor 1

1

2

Small-scale

0.479

High

354091

COIL
Coilin

1

1

High-throughput

0.479

High

354111

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.479

High

354132

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.479

High

354141

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

354142

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

354145

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

2

High-throughput

0.479

High

354159

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

354163

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

354166

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

2

High-throughput

0.479

High

354179

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

354183

T106B
Transmembrane protein 106B

1

2

High-throughput

0.479

High

354191

ALK
ALK tyrosine kinase receptor

1

3

Small-scale

0.479

High

354075

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

354092

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

354096

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

354099

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

354106

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

354114

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

354129

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

354152

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.458

High

354167

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

354170

DERL1
Derlin-1

1

0

High-throughput

0.458

High

354180

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

354085

SC6A2
Sodium-dependent noradrenaline transporter

1

7

High-throughput

0.445

High

354098

S6A12
Sodium- and chloride-dependent betaine transporter

1

7

High-throughput

0.445

High

354103

CCR9
C-C chemokine receptor type 9

1

6

High-throughput

0.445

High

354116

S15A2
Solute carrier family 15 member 2

1

2

High-throughput

0.445

High

354117

VACHT
Vesicular acetylcholine transporter

1

1

High-throughput

0.445

High

354122

CTL4
Choline transporter-like protein 4

1

2

High-throughput

0.445

High

354126

S22AA
Solute carrier family 22 member 10

1

7

High-throughput

0.445

High

354127

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.445

High

354150

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

354154

LPAR1
Lysophosphatidic acid receptor 1

1

1

High-throughput

0.445

High

354171

S12A9
Solute carrier family 12 member 9

1

2

High-throughput

0.445

High

354173

S6A16
Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

1

7

High-throughput

0.445

High

354176

S6A17
Sodium-dependent neutral amino acid transporter SLC6A17

1

7

High-throughput

0.445

High

354196

S22A7
Solute carrier family 22 member 7

1

7

High-throughput

0.445

High

240412

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.437

High

354071

ISG15
Ubiquitin-like protein ISG15

1

1

High-throughput

0.437

High

354079

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.437

High

354081

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

354086

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

354090

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

354093

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

354108

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

354130

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

354148

RBCC1
RB1-inducible coiled-coil protein 1

1

1

High-throughput

0.437

High

354184

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

248822

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

354074

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

354124

SL9C2
Sodium/hydrogen exchanger 11

1

0

High-throughput

0.426

High

354137

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.426

High

354151

S13A3
Na(+)/dicarboxylate cotransporter 3

1

0

High-throughput

0.426

High

354165

S26A8
Testis anion transporter 1

1

0

High-throughput

0.426

High

354185

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.426

High

354192

S45A2
Membrane-associated transporter protein

1

0

High-throughput

0.426

High

354195

FADS3
Fatty acid desaturase 3

1

0

High-throughput

0.426

High

354197

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.426

High

354136

SVOP
Synaptic vesicle 2-related protein

1

6

High-throughput

0.407

High

354144

ZNT7
Zinc transporter 7

1

3

High-throughput

0.407

High

141777

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

0

High-throughput

0.279

Low

337158

APOM
Apolipoprotein M

1

0

High-throughput

0.279

Low

354080

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.279

Low

354110

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.279

Low

354125

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.279

Low

354139

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.279

Low

354155

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

354160

ESPB1
Epididymal sperm-binding protein 1

1

0

High-throughput

0.279

Low

354190

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

354153

AP3S1
AP-3 complex subunit sigma-1

1

0

High-throughput

0.269

Low

105042

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

139797

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

293001

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

354068

P53
Cellular tumor antigen p53

1

0

High-throughput

0.249

Low

354082

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

354115

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

354118

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

354119

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

0

High-throughput

0.249

Low

354123

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

354140

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

354156

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.249

Low

354177

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

354188

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

354084

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

354104

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.232

Low

354169

S35A5
UDP-sugar transporter protein SLC35A5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025