Protein: ABCA3
Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form]

Gene: ABCA3
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q99758

Gene Ontology (top 5):
GO:0005319 - lipid transporter activity
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

821761

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.770

High

1351227

MCLN3
Mucolipin-3

3

0

High-throughput

0.638

High

855378

5HT3A
5-hydroxytryptamine receptor 3A

2

5

High-throughput

0.628

High

1057574

ACHD
Acetylcholine receptor subunit delta

2

2

High-throughput

0.628

High

1292692

TMPSC
Transmembrane protease serine 12

2

2

High-throughput

0.628

High

1316357

AGRG5
Adhesion G-protein coupled receptor G5

2

1

High-throughput

0.628

High

1390867

ASIC4
Acid-sensing ion channel 4

2

1

High-throughput

0.628

High

1407221

TMM9B
Transmembrane protein 9B

2

1

High-throughput

0.628

High

1332616

I17RC
Interleukin-17 receptor C

2

0

High-throughput

0.602

High

1359351

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

3

High-throughput

0.574

High

1392439

TECT2
Tectonic-2

2

1

High-throughput

0.574

High

835466

5HT2B
5-hydroxytryptamine receptor 2B

1

4

High-throughput

0.541

High

132647

UPK1A
Uroplakin-1a

1

2

High-throughput

0.536

High

607977

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

2

High-throughput

0.536

High

688680

NKG2C
NKG2-C type II integral membrane protein

1

6

High-throughput

0.536

High

1203780

TTMP
TPA-induced transmembrane protein

1

3

High-throughput

0.536

High

1334527

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.536

High

1407217

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

1407222

PCDBG
Protocadherin beta-16

1

3

High-throughput

0.536

High

417705

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

High-throughput

0.533

High

829920

PMEL
Melanocyte protein PMEL

1

0

High-throughput

0.513

High

1195457

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1325159

TM130
Transmembrane protein 130

1

0

High-throughput

0.513

High

1336063

ARRD4
Arrestin domain-containing protein 4

1

0

High-throughput

0.513

High

1407214

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1392285

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.489

High

1407225

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

3

High-throughput

0.489

High

568086

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

4

High-throughput

0.479

High

931436

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

1

High-throughput

0.479

High

989867

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

5

High-throughput

0.479

High

1036242

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

2

High-throughput

0.479

High

1042778

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

2

High-throughput

0.479

High

1155178

EREP1
Endosomal transmembrane epsin interactor 1

1

1

High-throughput

0.479

High

1192284

ZACN
Ligand-gated cation channel ZACN

1

6

High-throughput

0.479

High

1270961

RHOU
Rho-related GTP-binding protein RhoU

1

7

High-throughput

0.479

High

212475

SPIT2
Kunitz-type protease inhibitor 2

1

0

High-throughput

0.458

High

1407226

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

963459

STXB1
Syntaxin-binding protein 1

1

1

High-throughput

0.457

High

388447

B3AT
Band 3 anion transport protein

1

3

High-throughput

0.445

High

877713

SL9A3
Sodium/hydrogen exchanger 3

1

3

High-throughput

0.445

High

933538

S12A3
Solute carrier family 12 member 3

1

1

High-throughput

0.445

High

1102806

UT1
Urea transporter 1

1

1

High-throughput

0.445

High

1277282

S46A3
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3

1

2

High-throughput

0.445

High

1288155

SL9B2
Sodium/hydrogen exchanger 9B2

1

5

High-throughput

0.445

High

1340556

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.445

High

1407215

S46A2
Solute carrier family 46 member 2

1

3

High-throughput

0.445

High

1407220

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

1

High-throughput

0.445

High

1407223

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

1

High-throughput

0.445

High

1407227

S22AE
Solute carrier family 22 member 14

1

1

High-throughput

0.445

High

1407228

S27A6
Long-chain fatty acid transport protein 6

1

4

High-throughput

0.445

High

1255232

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

190469

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.426

High

653525

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

876439

EAA4
Excitatory amino acid transporter 4

1

0

High-throughput

0.426

High

880811

NRAM1
Natural resistance-associated macrophage protein 1

1

0

High-throughput

0.426

High

1238891

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

1334279

S38A9
Neutral amino acid transporter 9

1

0

High-throughput

0.426

High

1402845

DIRC2
Solute carrier family 49 member 4

1

0

High-throughput

0.426

High

1407216

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

1407218

MFSD1
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.426

High

1407224

SO1C1
Solute carrier organic anion transporter family member 1C1

1

0

High-throughput

0.426

High

943538

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

1

High-throughput

0.407

High

1242207

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.407

High

1352568

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

1

High-throughput

0.407

High

1198746

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

1407219

MANS1
MANSC domain-containing protein 1

1

0

High-throughput

0.279

Low

946585

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025