Protein: SPE39
Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction)

Gene: SPE39, VIPAS39
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q9H9C1

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005770 - late endosome
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431541

VP33B
Vacuolar protein sorting-associated protein 33B

14

10

Small-scale

0.987

High

1383680

VP33A
Vacuolar protein sorting-associated protein 33A

1

10

Small-scale

0.665

High

257177

CCD22
Coiled-coil domain-containing protein 22

3

0

High-throughput

0.634

High

1315207

GT252
Procollagen galactosyltransferase 2

2

1

High-throughput

0.628

High

1436989

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

2

1

High-throughput

0.611

High

246141

KIF1B
Kinesin-like protein KIF1B

2

0

High-throughput

0.602

High

888819

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

14

Small-scale

0.554

High

251968

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

1

High-throughput

0.536

High

1114327

CUL3
Cullin-3

1

1

High-throughput

0.536

High

730253

1433B
14-3-3 protein beta/alpha

1

0

High-throughput

0.513

High

1420060

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

1436991

CHMP3
Charged multivesicular body protein 3

1

0

High-throughput

0.513

High

1436992

WASF2
Actin-binding protein WASF2

1

0

High-throughput

0.513

High

390767

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

189850

STX7
Syntaxin-7

1

5

High-throughput

0.479

High

218791

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

226209

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

242962

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

630976

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.479

High

901580

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

1255583

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1433919

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

540681

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

976569

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1276322

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1362008

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

589718

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

696538

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

1312260

MIRO2
Mitochondrial Rho GTPase 2

1

1

High-throughput

0.437

High

1331255

ARL10
ADP-ribosylation factor-like protein 10

1

1

High-throughput

0.437

High

1204677

BEX5
Protein BEX5

1

0

High-throughput

0.426

High

337517

MATN4
Matrilin-4

2

0

High-throughput

0.328

High

1286411

LYG2
Lysozyme g-like protein 2

2

0

High-throughput

0.328

High

553076

PIP
Prolactin-inducible protein

2

0

High-throughput

0.313

High

866396

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.279

Low

186032

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

1233491

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1436990

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.249

Low

344325

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025