Protein: CCD22
Coiled-coil domain-containing protein 22

Gene: CCD22, CCDC22
Organism: Homo sapiens
Interactions: 144
UniProt ID: O60826

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005768 - endosome
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0006878 - intracellular copper ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257124

CCD93
Coiled-coil domain-containing protein 93

11

10

Small-scale

0.981

High

257145

COMD1
COMM domain-containing protein 1

9

1

Small-scale

0.976

High

257174

COMD4
COMM domain-containing protein 4

7

1

Small-scale

0.967

High

257204

COMDA
COMM domain-containing protein 10

6

10

Small-scale

0.956

High

257187

COMD9
COMM domain-containing protein 9

7

0

Small-scale

0.919

High

257172

COMD5
COMM domain-containing protein 5

7

0

Small-scale

0.916

High

257184

COMD8
COMM domain-containing protein 8

6

0

Small-scale

0.903

High

257190

COMD3
COMM domain-containing protein 3

8

1

Small-scale

0.867

High

257138

COMD2
COMM domain-containing protein 2

7

2

Small-scale

0.864

High

257136

COMD6
COMM domain-containing protein 6

7

0

Small-scale

0.810

High

257137

COMD7
COMM domain-containing protein 7

7

0

Small-scale

0.808

High

257134

VP35L
VPS35 endosomal protein-sorting factor-like

8

1

Small-scale

0.752

High

257191

VPS29
Vacuolar protein sorting-associated protein 29

6

1

High-throughput

0.734

High

257110

MTMR2
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2

5

3

High-throughput

0.716

High

257149

DEN10
DENN domain-containing protein 10

7

0

High-throughput

0.714

High

171051

VP26C
Vacuolar protein sorting-associated protein 26C

5

4

High-throughput

0.709

High

257151

PSPC1
Paraspeckle component 1

4

3

High-throughput

0.697

High

257175

VP33B
Vacuolar protein sorting-associated protein 33B

3

4

High-throughput

0.689

High

257115

PCM1
Pericentriolar material 1 protein

4

4

High-throughput

0.683

High

257097

PSMD7
26S proteasome non-ATPase regulatory subunit 7

3

5

High-throughput

0.667

High

257186

ABI2
Abl interactor 2

3

10

High-throughput

0.662

High

257177

SPE39
Spermatogenesis-defective protein 39 homolog

3

0

High-throughput

0.634

High

257141

ABI1
Abl interactor 1

2

9

High-throughput

0.628

High

257144

KIF2B
Kinesin-like protein KIF2B

2

4

High-throughput

0.628

High

257158

CYFP2
Cytoplasmic FMR1-interacting protein 2

2

1

High-throughput

0.628

High

257169

SPAG5
Sperm-associated antigen 5

2

20

High-throughput

0.628

High

257179

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

2

4

High-throughput

0.628

High

257157

DTBP1
Dysbindin

2

1

High-throughput

0.611

High

63286

ODAD3
Outer dynein arm-docking complex subunit 3

3

19

High-throughput

0.609

High

257135

K1C27
Keratin, type I cytoskeletal 27

2

13

High-throughput

0.606

High

257123

TR16L
Tripartite motif-containing protein 16-like protein

3

4

High-throughput

0.604

High

257079

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

2

0

High-throughput

0.602

High

257199

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.602

High

257094

NUP62
Nuclear pore glycoprotein p62

2

4

High-throughput

0.601

High

257165

SCLT1
Sodium channel and clathrin linker 1

2

19

High-throughput

0.588

High

217023

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

257087

POTEI
POTE ankyrin domain family member I

2

8

High-throughput

0.574

High

257162

F167A
Protein FAM167A

2

4

High-throughput

0.574

High

257103

ACTG
Actin, cytoplasmic 2

1

8

High-throughput

0.573

High

257107

CAMP2
Calmodulin-regulated spectrin-associated protein 2

2

10

High-throughput

0.571

High

257111

CUL1
Cullin-1

1

20

Small-scale

0.565

High

257113

CUL3
Cullin-3

1

20

Small-scale

0.554

High

257089

ARSA
Arylsulfatase A

2

3

High-throughput

0.553

High

250184

VINEX
Vinexin

1

8

High-throughput

0.536

High

252797

EXOC3
Exocyst complex component 3

1

1

High-throughput

0.536

High

257078

KRT38
Keratin, type I cuticular Ha8

1

19

High-throughput

0.536

High

257080

TRI16
Tripartite motif-containing protein 16

1

5

High-throughput

0.536

High

257088

ARAF
Serine/threonine-protein kinase A-Raf

1

13

High-throughput

0.536

High

257092

BMI1
Polycomb complex protein BMI-1

1

8

High-throughput

0.536

High

257096

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

257100

UBC12
NEDD8-conjugating enzyme Ubc12

1

3

High-throughput

0.536

High

257106

PRDX1
Peroxiredoxin-1

1

2

High-throughput

0.536

High

257112

CUL2
Cullin-2

1

20

Small-scale

0.536

High

257114

MAP7
Ensconsin

1

17

High-throughput

0.536

High

257116

NONO
Non-POU domain-containing octamer-binding protein

1

3

High-throughput

0.536

High

257125

WAC2A
WASH complex subunit 2A

1

3

Small-scale

0.536

High

257167

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

4

High-throughput

0.536

High

257170

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

3

High-throughput

0.536

High

257180

DISC1
Disrupted in schizophrenia 1 protein

1

6

High-throughput

0.536

High

257185

NDE1
Nuclear distribution protein nudE homolog 1

1

19

High-throughput

0.536

High

257194

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

8

High-throughput

0.536

High

257205

OAS3
2'-5'-oligoadenylate synthase 3

1

1

High-throughput

0.536

High

257160

BORC6
BLOC-1-related complex subunit 6

2

3

High-throughput

0.533

High

257146

USBP1
Harmonin-binding protein USHBP1

1

18

High-throughput

0.523

High

134493

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

251351

GMDS
GDP-mannose 4,6 dehydratase

1

0

High-throughput

0.513

High

257119

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

High-throughput

0.513

High

257121

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.513

High

257148

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.513

High

257153

STMN2
Stathmin-2

1

0

High-throughput

0.513

High

257159

TOE1
Target of EGR1 protein 1

1

0

High-throughput

0.513

High

257196

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

257200

FA32A
Protein FAM32A

1

0

High-throughput

0.513

High

257166

MIA2
Melanoma inhibitory activity protein 2

2

20

High-throughput

0.504

High

257102

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.493

High

257098

PLXA3
Plexin-A3

1

2

High-throughput

0.489

High

257104

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

8

High-throughput

0.489

High

257118

CNGA3
Cyclic nucleotide-gated channel alpha-3

1

5

High-throughput

0.489

High

257130

TRI72
Tripartite motif-containing protein 72

1

4

High-throughput

0.489

High

257139

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

5

High-throughput

0.489

High

257140

SULF2
Extracellular sulfatase Sulf-2

1

3

High-throughput

0.489

High

257142

SYCE1
Synaptonemal complex central element protein 1

1

3

High-throughput

0.489

High

257163

ODAD1
Outer dynein arm-docking complex subunit 1

1

19

High-throughput

0.489

High

257173

DRC3
Dynein regulatory complex subunit 3

1

9

High-throughput

0.489

High

257181

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

9

High-throughput

0.489

High

257202

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

6

High-throughput

0.489

High

163868

NDC80
Kinetochore protein NDC80 homolog

1

17

High-throughput

0.479

High

212749

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

2

High-throughput

0.479

High

257076

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

257077

OFD1
Centriole and centriolar satellite protein OFD1

1

3

High-throughput

0.479

High

257081

HERC2
E3 ubiquitin-protein ligase HERC2

1

5

High-throughput

0.479

High

257082

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

257083

K1C18
Keratin, type I cytoskeletal 18

1

16

High-throughput

0.479

High

257084

K2C8
Keratin, type II cytoskeletal 8

1

9

High-throughput

0.479

High

257086

K1C19
Keratin, type I cytoskeletal 19

1

13

High-throughput

0.479

High

257090

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

257091

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

257093

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

257095

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

257099

ACTB
Actin, cytoplasmic 1

1

9

High-throughput

0.479

High

257101

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

257105

TLE2
Transducin-like enhancer protein 2

1

17

High-throughput

0.479

High

257108

STX4
Syntaxin-4

1

7

High-throughput

0.479

High

257117

ZYX
Zyxin

1

7

High-throughput

0.479

High

257126

CP135
Centrosomal protein of 135 kDa

1

18

High-throughput

0.479

High

257127

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.479

High

257131

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

257132

CE128
Centrosomal protein of 128 kDa

1

20

High-throughput

0.479

High

257143

NIN
Ninein

1

20

High-throughput

0.479

High

257152

CUL5
Cullin-5

1

20

Small-scale

0.479

High

257154

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

2

High-throughput

0.479

High

257161

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

19

High-throughput

0.479

High

257164

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.479

High

257178

MED4
Mediator of RNA polymerase II transcription subunit 4

1

5

High-throughput

0.479

High

257192

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

257197

FBW1A
F-box/WD repeat-containing protein 1A

1

9

Small-scale

0.479

High

257198

NINL
Ninein-like protein

1

20

High-throughput

0.479

High

257203

WAC2C
WASH complex subunit 2C

1

3

Small-scale

0.479

High

257195

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.460

High

257109

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

257183

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.458

High

257168

VPS35
Vacuolar protein sorting-associated protein 35

1

1

Small-scale

0.445

High

257176

GAN
Gigaxonin

1

2

High-throughput

0.445

High

71409

ARG33
Rho guanine nucleotide exchange factor 33

1

1

High-throughput

0.437

High

257129

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.437

High

257133

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

1

High-throughput

0.437

High

257155

VP33A
Vacuolar protein sorting-associated protein 33A

1

4

High-throughput

0.437

High

257182

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

257188

SEP10
Septin-10

1

2

High-throughput

0.437

High

257193

XPO7
Exportin-7

1

4

High-throughput

0.437

High

71024

A8MTY9
VPS26 endosomal protein sorting factor C

1

1

High-throughput

0.407

High

116508

H7C1C9
Rho guanine nucleotide exchange factor 33

1

1

High-throughput

0.407

High

257085

HEPS
Serine protease hepsin

1

5

High-throughput

0.407

High

257120

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

257156

HDA11
Histone deacetylase 11

1

11

High-throughput

0.407

High

257171

KXDL1
KxDL motif-containing protein 1

1

3

High-throughput

0.407

High

257189

ABI3
ABI gene family member 3

1

11

High-throughput

0.407

High

248546

FADS1
Acyl-CoA

1

0

High-throughput

0.279

Low

257122

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

257128

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.279

Low

257147

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

257150

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

257201

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.279

Low

50883

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025