Protein: TPRKB
EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein)

Gene: TPRKB
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q9Y3C4

Gene Ontology (top 5):
GO:0000408 - EKC/KEOPS complex
GO:0002949 - tRNA threonylcarbamoyladenosine modification
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1402184

PRPK
EKC/KEOPS complex subunit TP53RK

11

1

Small-scale

0.982

High

1446327

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

4

1

Small-scale

0.694

High

1339058

NUP43
Nucleoporin Nup43

4

0

High-throughput

0.661

High

1449168

MBIP1
MAP3K12-binding inhibitory protein 1

4

0

High-throughput

0.661

High

1129288

LAGE3
EKC/KEOPS complex subunit LAGE3

3

1

Small-scale

0.650

High

572294

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.549

High

210472

MSH5
MutS protein homolog 5

1

0

High-throughput

0.513

High

294958

POP7
Ribonuclease P protein subunit p20

1

0

High-throughput

0.513

High

1160352

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1333058

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.513

High

1450830

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.513

High

1491170

COMDA
COMM domain-containing protein 10

1

0

High-throughput

0.513

High

595654

H15
Histone H1.5

1

0

High-throughput

0.493

High

1256213

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

348008

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

1007620

PRAME
Melanoma antigen preferentially expressed in tumors

1

0

Small-scale

0.458

High

1413536

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.426

High

1417406

GON7
EKC/KEOPS complex subunit GON7

1

0

Small-scale

0.426

High

1429216

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.426

High

1410920

GORS1
Golgi reassembly-stacking protein 1

3

0

High-throughput

0.345

High

1181213

ANO4
Anoctamin-4

2

0

High-throughput

0.313

High

1364791

TICN2
Testican-2

1

0

High-throughput

0.279

Low

1395650

CH076
Uncharacterized protein C8orf76

1

0

High-throughput

0.279

Low

1295050

TMM25
Transmembrane protein 25

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025