Protein: DCST1
E3 ubiquitin-protein ligase DCST1 (EC 2.3.2.27) (DC-STAMP domain-containing protein 1) (RING-type E3 ubiquitin transferase)

Gene: DCST1
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q5T197

Gene Ontology (top 5):
GO:0002080 - acrosomal membrane
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0007342 - fusion of sperm to egg plasma membrane involved in single fertilization
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

913137

STAT2
Signal transducer and activator of transcription 2

2

0

Small-scale

0.576

High

1211812

KCNT2
Potassium channel subfamily T member 2

1

1

High-throughput

0.536

High

243803

ADCY3
Adenylate cyclase type 3

1

0

High-throughput

0.513

High

1114873

CUL4A
Cullin-4A

1

0

High-throughput

0.513

High

1138965

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

0

High-throughput

0.513

High

1211814

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.513

High

1211816

BT2A2
Butyrophilin subfamily 2 member A2

1

0

High-throughput

0.513

High

1211820

KCNG1
Voltage-gated potassium channel regulatory subunit KCNG1

1

0

High-throughput

0.513

High

413982

P53
Cellular tumor antigen p53

1

0

Small-scale

0.480

High

241921

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

873916

INAR2
Interferon alpha/beta receptor 2

1

0

Small-scale

0.458

High

1211813

ARL10
ADP-ribosylation factor-like protein 10

1

0

High-throughput

0.279

Low

1211817

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1211818

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

1

0

High-throughput

0.279

Low

1211819

ABCB9
ABC-type oligopeptide transporter ABCB9

1

0

High-throughput

0.279

Low

1211821

SNX14
Sorting nexin-14

1

0

High-throughput

0.279

Low

1211815

NEDD1
Protein NEDD1

1

0

High-throughput

0.249

Low

1211067

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025