Protein: INAR2
Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2)

Gene: INAR2, IFNAR2
Organism: Homo sapiens
Interactions: 40
UniProt ID: P48551

Gene Ontology (top 5):
GO:0004905 - type I interferon receptor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

378250

IFNA2
Interferon alpha-2

6

5

Small-scale

0.953

High

602882

INAR1
Interferon alpha/beta receptor 1

3

2

Small-scale

0.827

High

873904

STAT2
Signal transducer and activator of transcription 2

8

2

Small-scale

0.753

High

873903

INAR2
Interferon alpha/beta receptor 2

2

0

Small-scale

0.728

High

838015

STAT1
Signal transducer and activator of transcription 1-alpha/beta

4

2

Small-scale

0.700

High

873912

I10R1
Interleukin-10 receptor subunit alpha

1

2

Small-scale

0.665

High

658659

JAK1
Tyrosine-protein kinase JAK1

3

0

Small-scale

0.646

High

292818

GRAP2
GRB2-related adapter protein 2

3

0

High-throughput

0.634

High

873907

IRF9
Interferon regulatory factor 9

2

1

Small-scale

0.628

High

378232

IFNA1
Interferon alpha-1/13

1

5

Small-scale

0.618

High

378316

IFNA5
Interferon alpha-5

1

5

Small-scale

0.618

High

378368

IFNB
Interferon beta

1

5

Small-scale

0.618

High

420231

IFNW1
Interferon omega-1

1

5

Small-scale

0.618

High

746548

IFNA8
Interferon alpha-8

1

5

Small-scale

0.618

High

647307

IL10
Interleukin-10

1

0

Small-scale

0.586

High

873921

IL22
Interleukin-22

1

0

Small-scale

0.586

High

873919

CBP
CREB-binding protein

1

3

Small-scale

0.506

High

568776

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

0

Small-scale

0.480

High

873909

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

Small-scale

0.458

High

873911

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

873914

PCBP2
Poly(rC)-binding protein 2

1

0

Small-scale

0.458

High

873916

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

Small-scale

0.458

High

873920

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

Small-scale

0.458

High

186516

TRI18
E3 ubiquitin-protein ligase Midline-1

1

3

Small-scale

0.437

High

623183

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

Small-scale

0.437

High

873908

RING1
E3 ubiquitin-protein ligase RING1

1

1

Small-scale

0.437

High

873910

EP300
Histone acetyltransferase p300

1

3

Small-scale

0.437

High

873913

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

3

Small-scale

0.437

High

873917

TRI69
E3 ubiquitin-protein ligase TRIM69

1

1

Small-scale

0.437

High

873923

UBP18
Ubl carboxyl-terminal hydrolase 18

5

0

Small-scale

0.368

High

873905

RACK1
Small ribosomal subunit protein RACK1

2

0

Small-scale

0.338

High

873918

PPR3B
Protein phosphatase 1 regulatory subunit 3B

1

0

High-throughput

0.282

High

123234

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.279

Low

272626

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

Small-scale

0.249

Low

832671

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.249

Low

873906

XIAP
E3 ubiquitin-protein ligase XIAP

1

0

Small-scale

0.249

Low

873915

HERC4
Probable E3 ubiquitin-protein ligase HERC4

1

0

Small-scale

0.249

Low

873922

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

0

Small-scale

0.249

Low

873924

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025