Protein: PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q)

Gene: PIGQ
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9BRB3

Gene Ontology (top 5):
GO:0000506 - glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005975 - carbohydrate metabolic process
GO:0006506 - GPI anchor biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126352

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

3

0

Small-scale

0.646

High

790175

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

3

0

Small-scale

0.638

High

829921

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.602

High

1363774

PIGC
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

1

1

Small-scale

0.586

High

1332617

I17RC
Interleukin-17 receptor C

2

1

High-throughput

0.574

High

317084

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

Small-scale

0.513

High

595101

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

0

High-throughput

0.513

High

1392289

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

943450

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

1

0

Small-scale

0.493

High

537803

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.489

High

931083

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.489

High

1411071

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

1

High-throughput

0.489

High

178374

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

1346768

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

1

High-throughput

0.445

High

230413

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.426

High

1347642

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.426

High

1411075

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

0

High-throughput

0.426

High

1411078

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.426

High

290977

PPM1B
Protein phosphatase 1B

1

1

High-throughput

0.407

High

777006

PPM1A
Protein phosphatase 1A

1

1

High-throughput

0.407

High

1180861

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

1

High-throughput

0.407

High

1411081

S4A7
Sodium bicarbonate cotransporter 3

1

1

High-throughput

0.407

High

1411079

TN13B
Tumor necrosis factor ligand superfamily member 13B

3

0

High-throughput

0.347

High

596772

DPEP1
Dipeptidase 1

2

0

High-throughput

0.328

High

1248492

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.328

High

1355920

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

0

High-throughput

0.328

High

1392444

TECT2
Tectonic-2

2

0

High-throughput

0.328

High

1411074

I17RB
Interleukin-17 receptor B

2

0

High-throughput

0.328

High

1411080

PCDC2
Protocadherin alpha-C2

2

0

High-throughput

0.328

High

1393195

TM169
Transmembrane protein 169

2

0

High-throughput

0.313

High

1411076

RN181
E3 ubiquitin-protein ligase RNF181

2

0

High-throughput

0.313

High

248502

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.279

Low

270172

LRP3
Low-density lipoprotein receptor-related protein 3

1

0

High-throughput

0.279

Low

303693

JTB
Protein JTB

1

0

High-throughput

0.279

Low

1211818

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

High-throughput

0.279

Low

1233263

ELP2
Elongator complex protein 2

1

0

High-throughput

0.279

Low

1250395

DPP8
Dipeptidyl peptidase 8

1

0

High-throughput

0.279

Low

1411072

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1411073

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.279

Low

1411077

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1154002

SMAD1
Mothers against decapentaplegic homolog 1

1

0

High-throughput

0.265

Low

989094

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.261

Low

858706

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

0

High-throughput

0.249

Low

1407446

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.238

Low

211943

SPIT1
Kunitz-type protease inhibitor 1

1

0

High-throughput

0.232

Low

296738

TUSC2
Tumor suppressor candidate 2

1

0

High-throughput

0.232

Low

575194

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.232

Low

704066

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

1048386

ACVR1
Activin receptor type-1

1

0

High-throughput

0.232

Low

1351524

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.232

Low

1383451

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.232

Low

1389570

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025