Protein: PR15B
Protein phosphatase 1 regulatory subunit 15B

Gene: PR15B, PPP1R15B
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q5SWA1

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0001933 - negative regulation of protein phosphorylation
GO:0005783 - endoplasmic reticulum
GO:0006417 - regulation of translation
GO:0006983 - ER overload response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

967787

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

4

2

Small-scale

0.855

High

786652

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

5

2

Small-scale

0.796

High

944916

TMPS3
Transmembrane protease serine 3

2

0

High-throughput

0.528

High

1211076

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.528

High

968331

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.514

High

466908

ACM4
Muscarinic acetylcholine receptor M4

2

1

High-throughput

0.504

High

1207862

S27A3
Long-chain fatty acid transport protein 3

1

4

High-throughput

0.445

High

1211070

S27A1
Long-chain fatty acid transport protein 1

1

4

High-throughput

0.445

High

1211092

S27A5
Long-chain fatty acid transport protein 5

1

4

High-throughput

0.445

High

547322

CP19A
Aromatase

1

0

High-throughput

0.426

High

1126300

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.426

High

1185809

PTHD3
Patched domain-containing protein 3

1

0

High-throughput

0.426

High

1203676

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.426

High

1211068

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

0

High-throughput

0.426

High

1211071

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.426

High

1211079

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.426

High

171472

S27A2
Long-chain fatty acid transport protein 2

1

4

High-throughput

0.407

High

477170

ACM5
Muscarinic acetylcholine receptor M5

1

1

High-throughput

0.407

High

663524

FSHR
Follicle-stimulating hormone receptor

1

2

High-throughput

0.407

High

877675

SL9A3
Sodium/hydrogen exchanger 3

1

3

High-throughput

0.407

High

1133776

SL9A5
Sodium/hydrogen exchanger 5

1

3

High-throughput

0.407

High

1211069

SL9A4
Sodium/hydrogen exchanger 4

1

3

High-throughput

0.407

High

1211075

KCNG4
Voltage-gated potassium channel regulatory subunit KCNG4

1

1

High-throughput

0.407

High

1211080

RXFP1
Relaxin receptor 1

1

1

High-throughput

0.407

High

1211086

SL9A2
Sodium/hydrogen exchanger 2

1

3

High-throughput

0.407

High

1211091

S27A6
Long-chain fatty acid transport protein 6

1

4

High-throughput

0.407

High

127687

TR10A
Tumor necrosis factor receptor superfamily member 10A

2

0

High-throughput

0.288

High

142132

NPT3
Sodium-dependent phosphate transport protein 3

2

0

High-throughput

0.288

High

845433

PE2R3
Prostaglandin E2 receptor EP3 subtype

2

0

High-throughput

0.288

High

1211088

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

2

0

High-throughput

0.288

High

783289

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.268

Low

1178978

ABCB5
ATP-binding cassette sub-family B member 5

1

0

High-throughput

0.249

Low

238538

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.238

Low

66441

ASB14
Ankyrin repeat and SOCS box protein 14

1

0

High-throughput

0.232

Low

66792

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.232

Low

270151

LRP3
Low-density lipoprotein receptor-related protein 3

1

0

High-throughput

0.232

Low

595057

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

0

High-throughput

0.232

Low

711555

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.232

Low

933520

S12A3
Solute carrier family 12 member 3

1

0

High-throughput

0.232

Low

1106784

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.232

Low

1126233

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

0

High-throughput

0.232

Low

1181202

ANO4
Anoctamin-4

1

0

High-throughput

0.232

Low

1211067

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

High-throughput

0.232

Low

1211072

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.232

Low

1211073

FGRL1
Fibroblast growth factor receptor-like 1

1

0

High-throughput

0.232

Low

1211074

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.232

Low

1211077

HPSE2
Inactive heparanase-2

1

0

High-throughput

0.232

Low

1211078

FGF14
Fibroblast growth factor 14

1

0

High-throughput

0.232

Low

1211081

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.232

Low

1211082

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.232

Low

1211083

PCD10
Protocadherin-10

1

0

High-throughput

0.232

Low

1211084

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.232

Low

1211085

MAP10
Microtubule-associated protein 10

1

0

High-throughput

0.232

Low

1211087

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.232

Low

1211089

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.232

Low

1211090

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

0

High-throughput

0.232

Low

1211093

O10H1
Olfactory receptor 10H1

1

0

High-throughput

0.232

Low

1211094

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025