Protein: HEPS
Serine protease hepsin (EC 3.4.21.106) (Transmembrane protease serine 1) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]

Gene: HEPS, HPN
Organism: Homo sapiens
Interactions: 96
UniProt ID: P05981

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

203015

COCH
Cochlin

1

4

High-throughput

0.691

High

341531

TPA
Tissue-type plasminogen activator

1

11

High-throughput

0.691

High

409493

DAF
Complement decay-accelerating factor

1

6

High-throughput

0.691

High

409495

INGR1
Interferon gamma receptor 1

1

1

High-throughput

0.691

High

409501

PEDF
Pigment epithelium-derived factor

1

20

High-throughput

0.691

High

409510

VLDLR
Very low-density lipoprotein receptor

1

6

High-throughput

0.691

High

409513

MFGM
Lactadherin

1

9

High-throughput

0.691

High

409521

MICA
MHC class I polypeptide-related sequence A

1

14

High-throughput

0.691

High

409529

LRP11
Low-density lipoprotein receptor-related protein 11

1

7

High-throughput

0.691

High

409542

NECT2
Nectin-2

1

15

High-throughput

0.691

High

409553

LRRC3
Leucine-rich repeat-containing protein 3

1

6

High-throughput

0.691

High

409568

EGFL7
Epidermal growth factor-like protein 7

1

11

High-throughput

0.691

High

409548

HPLN3
Hyaluronan and proteoglycan link protein 3

1

5

High-throughput

0.618

High

131866

UPK2
Uroplakin-2

2

2

High-throughput

0.606

High

409494

PSPC
Surfactant protein C

2

4

High-throughput

0.606

High

409515

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

2

High-throughput

0.606

High

409503

GLP1R
Glucagon-like peptide 1 receptor

1

5

Small-scale

0.552

High

151960

TOR1A
Torsin-1A

1

12

High-throughput

0.536

High

225289

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

2

High-throughput

0.536

High

266521

GPC4
Glypican-4

1

12

High-throughput

0.536

High

305340

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.536

High

409492

CATL1
Procathepsin L

1

3

High-throughput

0.536

High

409496

FBLN1
Fibulin-1

1

15

High-throughput

0.536

High

409497

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

4

High-throughput

0.536

High

409498

CALX
Calnexin

1

9

High-throughput

0.536

High

409499

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

7

High-throughput

0.536

High

409502

WNT5A
Protein Wnt-5a

1

2

High-throughput

0.536

High

409504

GLRB
Glycine receptor subunit beta

1

1

High-throughput

0.536

High

409505

LMAN1
Protein ERGIC-53

1

5

High-throughput

0.536

High

409506

GPC3
Glypican-3

1

12

High-throughput

0.536

High

409508

EPHB4
Ephrin type-B receptor 4

1

17

High-throughput

0.536

High

409511

GCNT1
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

1

2

High-throughput

0.536

High

409512

TGBR3
Transforming growth factor beta receptor type 3

1

7

High-throughput

0.536

High

409514

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

1

High-throughput

0.536

High

409516

TUSC3
Tumor suppressor candidate 3

1

1

High-throughput

0.536

High

409518

PDIA5
Protein disulfide-isomerase A5

1

5

High-throughput

0.536

High

409519

NOMO1
BOS complex subunit NOMO1

1

5

High-throughput

0.536

High

409520

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

3

High-throughput

0.536

High

409522

MKS3
Meckelin

1

2

High-throughput

0.536

High

409524

DIK1A
Divergent protein kinase domain 1A

1

2

High-throughput

0.536

High

409526

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

3

High-throughput

0.536

High

409528

GALT7
N-acetylgalactosaminyltransferase 7

1

14

High-throughput

0.536

High

409530

LSR
Lipolysis-stimulated lipoprotein receptor

1

2

High-throughput

0.536

High

409531

ERO1B
ERO1-like protein beta

1

2

High-throughput

0.536

High

409533

SULF1
Extracellular sulfatase Sulf-1

1

5

High-throughput

0.536

High

409535

GPC2
Glypican-2 [Cleaved into: Secreted glypican-2]

1

12

High-throughput

0.536

High

409537

GALT4
Polypeptide N-acetylgalactosaminyltransferase 4

1

14

High-throughput

0.536

High

409540

GOGA5
Golgin subfamily A member 5

1

3

High-throughput

0.536

High

409541

SCRB1
Scavenger receptor class B member 1

1

5

High-throughput

0.536

High

409543

GSLG1
Golgi apparatus protein 1

1

1

High-throughput

0.536

High

409544

EXT2
Exostosin-2

1

4

High-throughput

0.536

High

409546

C1GLC
C1GALT1-specific chaperone 1

1

11

High-throughput

0.536

High

409547

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.536

High

409549

TM9S2
Transmembrane 9 superfamily member 2

1

7

High-throughput

0.536

High

409550

ADPGK
ADP-dependent glucokinase

1

3

High-throughput

0.536

High

409552

CHID1
Chitinase domain-containing protein 1

1

1

High-throughput

0.536

High

409554

FUT8
Alpha-(1,6)-fucosyltransferase

1

1

High-throughput

0.536

High

409555

ULBP3
UL16-binding protein 3

1

14

High-throughput

0.536

High

409556

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

2

High-throughput

0.536

High

409557

TMX4
Thioredoxin-related transmembrane protein 4

1

14

High-throughput

0.536

High

409558

CRLD1
Cysteine-rich secretory protein LCCL domain-containing 1

1

6

High-throughput

0.536

High

409559

TOR3A
Torsin-3A

1

12

High-throughput

0.536

High

409560

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

7

High-throughput

0.536

High

409562

FZD3
Frizzled-3

1

3

High-throughput

0.536

High

409563

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

11

High-throughput

0.536

High

409565

DNJB9
DnaJ homolog subfamily B member 9

1

8

High-throughput

0.536

High

409566

B4GT7
Beta-1,4-galactosyltransferase 7

1

9

High-throughput

0.536

High

409569

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

13

High-throughput

0.536

High

409571

CCPG1
Cell cycle progression protein 1

1

1

High-throughput

0.536

High

409572

PPT2
Lysosomal thioesterase PPT2

1

1

High-throughput

0.536

High

409573

FND3A
Fibronectin type-III domain-containing protein 3A

1

8

High-throughput

0.536

High

409574

BACE2
Beta-secretase 2

1

3

High-throughput

0.536

High

409575

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

1

12

High-throughput

0.536

High

409576

POMT1
Protein O-mannosyl-transferase 1

1

5

High-throughput

0.536

High

409491

ADH1A
Alcohol dehydrogenase 1A

1

0

High-throughput

0.513

High

409517

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.513

High

337766

EGFR
Epidermal growth factor receptor

1

12

Small-scale

0.501

High

282394

STC2
Stanniocalcin-2

1

5

High-throughput

0.489

High

409500

TIMP3
Metalloproteinase inhibitor 3

1

2

High-throughput

0.489

High

409507

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

1

High-throughput

0.489

High

409509

INHBE
Inhibin beta E chain

1

6

High-throughput

0.489

High

409525

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

1

2

High-throughput

0.489

High

409527

D19L4
Probable C-mannosyltransferase DPY19L4

1

2

High-throughput

0.489

High

409532

GLBL2
Beta-galactosidase-1-like protein 2

1

2

High-throughput

0.489

High

409534

CHSS2
Chondroitin sulfate synthase 2

1

11

High-throughput

0.489

High

409538

PGLT1
Protein O-glucosyltransferase 1

1

2

High-throughput

0.489

High

409539

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

1

5

High-throughput

0.489

High

409564

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

4

High-throughput

0.489

High

409567

SUN2
SUN domain-containing protein 2

1

2

High-throughput

0.489

High

409570

PCOC2
Procollagen C-endopeptidase enhancer 2

1

14

High-throughput

0.489

High

409536

TOR2X
Prosalusin

1

12

High-throughput

0.437

High

409561

SP110
Sp110 nuclear body protein

1

3

High-throughput

0.437

High

409523

TOR2A
Torsin-2A

1

15

High-throughput

0.407

High

403472

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

1

0

High-throughput

0.279

Low

409545

TMM18
Transmembrane protein 18

1

0

High-throughput

0.279

Low

409551

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024