Protein: WIPI3
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B) (WIPI49-like protein)

Gene: WIPI3, WDR45B
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q5MNZ6

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0000425 - pexophagy
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1208376

GA2L1
GAS2-like protein 1

3

9

High-throughput

0.667

High

714173

PML
Protein PML

2

20

High-throughput

0.628

High

908208

BMX
Cytoplasmic tyrosine-protein kinase BMX

2

7

High-throughput

0.628

High

1208379

PKHA1
Pleckstrin homology domain-containing family A member 1

2

7

High-throughput

0.628

High

1145583

RCN1
Reticulocalbin-1

3

4

High-throughput

0.609

High

1208369

ARRD1
Arrestin domain-containing protein 1

3

8

High-throughput

0.609

High

928740

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

2

0

High-throughput

0.602

High

1199127

PKHO1
Pleckstrin homology domain-containing family O member 1

2

1

High-throughput

0.574

High

1208361

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

4

High-throughput

0.574

High

1208363

PMF1
Polyamine-modulated factor 1

2

0

High-throughput

0.559

High

911933

JAK3
Tyrosine-protein kinase JAK3

1

18

High-throughput

0.536

High

1193107

PKHN1
Pleckstrin homology domain-containing family N member 1

1

1

High-throughput

0.536

High

1208367

BAP18
BPTF-associated chromatin complex component 1

1

1

High-throughput

0.536

High

1208368

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

3

High-throughput

0.536

High

1208370

EIF1A
Probable RNA-binding protein EIF1AD

1

1

High-throughput

0.536

High

580399

ALDR
Aldo-keto reductase family 1 member B1

1

1

High-throughput

0.515

High

1208380

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

422273

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

155713

CUX2
Homeobox protein cut-like 2

1

19

High-throughput

0.489

High

162838

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

3

High-throughput

0.489

High

1161291

CCL15
C-C motif chemokine 15

1

2

High-throughput

0.489

High

1200309

ANR39
Ankyrin repeat domain-containing protein 39

1

9

High-throughput

0.489

High

1208360

AHDC1
Transcription factor Gibbin

1

1

High-throughput

0.489

High

1208362

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

2

High-throughput

0.489

High

1208365

HDGR2
Hepatoma-derived growth factor-related protein 2

1

11

High-throughput

0.489

High

1208371

TM263
Transmembrane protein 263

1

1

High-throughput

0.489

High

1208381

DPOE3
DNA polymerase epsilon subunit 3

1

3

High-throughput

0.489

High

1208382

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

1

High-throughput

0.489

High

1208384

RN181
E3 ubiquitin-protein ligase RNF181

1

5

High-throughput

0.489

High

1208385

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

3

High-throughput

0.489

High

630423

RAB3A
Ras-related protein Rab-3A

1

5

High-throughput

0.479

High

1208373

SNX27
Sorting nexin-27

1

5

High-throughput

0.479

High

1208375

MTMR9
Myotubularin-related protein 9

1

4

High-throughput

0.479

High

438959

DCUP
Uroporphyrinogen decarboxylase

1

0

High-throughput

0.458

High

1208378

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

4

High-throughput

0.445

High

690504

KAD4
Adenylate kinase 4, mitochondrial

1

1

High-throughput

0.437

High

695644

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.437

High

768368

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.437

High

1208364

DEFI8
Differentially expressed in FDCP 8 homolog

1

8

High-throughput

0.437

High

1208387

DS13B
Dual specificity protein phosphatase 13B

1

3

High-throughput

0.437

High

430009

JUN
Transcription factor Jun

1

19

High-throughput

0.407

High

873880

KCNJ5
G protein-activated inward rectifier potassium channel 4

2

0

High-throughput

0.328

High

1032007

TFAP4
Transcription factor AP-4

2

0

High-throughput

0.328

High

1200347

APRV1
Retroviral-like aspartic protease 1

2

0

High-throughput

0.328

High

1208366

CE024
UPF0461 protein C5orf24

2

0

High-throughput

0.328

High

1208388

CNPY2
Protein canopy homolog 2

2

0

High-throughput

0.328

High

50574

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.279

Low

158604

VCY1
Testis-specific basic protein Y 1

1

0

High-throughput

0.279

Low

415128

MT1F
Metallothionein-1F

1

0

High-throughput

0.279

Low

873398

LSS
Lanosterol synthase

1

0

High-throughput

0.279

Low

1013143

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.279

Low

1208372

P2RX5
P2X purinoceptor 5

1

0

High-throughput

0.279

Low

1208377

SPXN
Spexin

1

0

High-throughput

0.279

Low

1208383

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.279

Low

1208386

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.279

Low

1149490

SP17
Sperm surface protein Sp17

1

0

High-throughput

0.249

Low

1208374

UBX10
UBX domain-containing protein 10

1

0

High-throughput

0.249

Low

834979

S19A1
Reduced folate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025