Protein: PHB2
Prohibitin-2

Gene: PHB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: P50085

Gene Ontology (top 5):
GO:0000001 - mitochondrion inheritance
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006457 - protein folding
GO:0007005 - mitochondrion organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778521

PHB1
Prohibitin-1

5

14

Small-scale

0.926

High

764776

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

3

10

Small-scale

0.656

High

837179

PHB2
Prohibitin-2

1

13

High-throughput

0.618

High

772371

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

2

12

High-throughput

0.611

High

389952

VDAC1
Mitochondrial outer membrane protein porin 1

2

9

High-throughput

0.584

High

732934

MIC60
MICOS complex subunit MIC60

2

1

High-throughput

0.584

High

765516

OXA1
Mitochondrial inner membrane protein OXA1

2

2

High-throughput

0.584

High

826143

TOM22
Mitochondrial import receptor subunit TOM22

2

1

High-throughput

0.584

High

511958

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.521

High

751393

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.513

High

614725

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

530102

ATC1
Calcium-transporting ATPase 1

1

7

High-throughput

0.489

High

697160

ANP1
Mannan polymerase II complex ANP1 subunit

1

3

High-throughput

0.489

High

710313

SIP2
SNF1 protein kinase subunit beta-2

1

1

High-throughput

0.489

High

761481

MNN9
Mannan polymerase complexes subunit MNN9

1

3

High-throughput

0.489

High

766396

GEA2
ARF guanine-nucleotide exchange factor 2

1

1

High-throughput

0.489

High

810026

MNN11
Probable alpha-1,6-mannosyltransferase MNN11

1

1

High-throughput

0.489

High

333382

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

1

High-throughput

0.479

High

333443

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

1

High-throughput

0.479

High

335962

COX2
Cytochrome c oxidase subunit 2

1

4

High-throughput

0.479

High

336060

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

3

High-throughput

0.479

High

336093

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

3

High-throughput

0.479

High

336147

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

1

High-throughput

0.479

High

357322

RMAR
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.479

High

373274

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

424109

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

10

High-throughput

0.479

High

424218

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

10

High-throughput

0.479

High

435479

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

High-throughput

0.479

High

440192

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

1

High-throughput

0.479

High

478350

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

619749

TOM40
Mitochondrial import receptor subunit TOM40

1

1

High-throughput

0.479

High

628258

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

689521

RM41
Large ribosomal subunit protein uL23m

1

1

High-throughput

0.479

High

698318

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

1

High-throughput

0.479

High

699644

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

2

High-throughput

0.479

High

699937

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

2

High-throughput

0.479

High

705410

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

737186

LONM
Lon protease homolog, mitochondrial

1

5

Small-scale

0.479

High

748870

MIC12
MICOS complex subunit MIC12

1

1

Small-scale

0.479

High

753740

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

1

High-throughput

0.479

High

755061

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

2

High-throughput

0.479

High

837182

MCY1
Putative mitochondrial cysteine synthase

1

2

High-throughput

0.479

High

837183

RCF2
Respiratory supercomplex factor 2, mitochondrial

1

1

High-throughput

0.479

High

837185

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

837188

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

2

High-throughput

0.479

High

837192

ATG33
Autophagy-related protein 33

1

1

High-throughput

0.479

High

837198

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

1

High-throughput

0.479

High

837199

MIC10
MICOS complex subunit MIC10

1

1

Small-scale

0.479

High

763471

ERP2
Protein ERP2

1

1

High-throughput

0.470

High

576150

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.458

High

748496

OM14
Mitochondrial outer membrane protein OM14

1

0

Small-scale

0.458

High

774829

PUP1
PUP1 protein homolog

1

0

High-throughput

0.458

High

837184

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

837191

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

631011

KCC4
Probable serine/threonine-protein kinase KCC4

1

3

High-throughput

0.457

High

368213

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

424602

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.445

High

440064

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.445

High

494415

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

588148

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.445

High

707892

GCN1
eIF-2-alpha kinase activator GCN1

1

7

High-throughput

0.445

High

730996

MAOM
NAD-dependent malic enzyme, mitochondrial

1

1

High-throughput

0.445

High

747400

PHO88
SRP-independent targeting protein 3

1

1

High-throughput

0.445

High

837195

MDN1
Midasin

1

7

High-throughput

0.445

High

837197

RUVB2
RuvB-like protein 2

1

4

High-throughput

0.445

High

524386

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

660356

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

662739

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

745763

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

768901

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.437

High

774121

TM108
Protein TMA108

1

3

High-throughput

0.437

High

811174

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.437

High

837180

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.437

High

837181

PEX14
Peroxisomal membrane protein PEX14

1

2

Small-scale

0.437

High

837189

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.437

High

837193

SGO1
Shugoshin

1

1

High-throughput

0.437

High

837194

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.437

High

837196

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

356588

H4
Histone H4

1

2

High-throughput

0.407

High

360949

TBB
Tubulin beta chain

1

9

High-throughput

0.407

High

399544

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

454397

TBA1
Tubulin alpha-1 chain

1

5

High-throughput

0.407

High

485771

IF4A
ATP-dependent RNA helicase eIF4A

1

5

High-throughput

0.407

High

556158

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.407

High

687429

EF2
Elongation factor 2

1

4

High-throughput

0.407

High

700516

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.407

High

706372

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.407

High

746521

IMB2
Importin subunit beta-2

1

8

High-throughput

0.407

High

752938

YHI0
Putative proline--tRNA ligase YHR020W

1

2

High-throughput

0.407

High

753422

ECM29
Proteasome component ECM29

1

8

High-throughput

0.407

High

784387

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.407

High

804806

RSSA2
Small ribosomal subunit protein uS2B

1

3

High-throughput

0.407

High

837186

SNA2
Protein SNA2

1

1

High-throughput

0.407

High

837187

ACT
Actin

1

4

High-throughput

0.407

High

837190

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.407

High

697592

KA122
Importin beta-like protein KAP122

1

0

High-throughput

0.279

Low

710446

SAS3
Histone acetyltransferase SAS3

1

0

Small-scale

0.279

Low

730485

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.261

Low

753880

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024