Protein: PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta)

Gene: PCCB
Organism: Homo sapiens
Interactions: 128
UniProt ID: P05166

Gene Ontology (top 5):
GO:0004658 - propionyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

398215

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

4

18

Small-scale

0.909

High

398394

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

2

18

High-throughput

0.789

High

398320

PYC
Pyruvate carboxylase, mitochondrial

1

18

High-throughput

0.618

High

398351

ACACA
Acetyl-CoA carboxylase 1

1

18

High-throughput

0.618

High

398405

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

16

High-throughput

0.618

High

226253

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

398350

ACTN3
Alpha-actinin-3

2

0

High-throughput

0.580

High

176343

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

2

High-throughput

0.536

High

258648

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

1

High-throughput

0.536

High

270904

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

1

High-throughput

0.536

High

398318

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

4

High-throughput

0.536

High

398330

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

3

High-throughput

0.536

High

398337

STK19
Inactive serine/threonine-protein kinase 19

1

1

High-throughput

0.536

High

398348

CDK17
Cyclin-dependent kinase 17

1

3

High-throughput

0.536

High

398353

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.536

High

398363

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

1

High-throughput

0.536

High

398389

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

1

High-throughput

0.536

High

398403

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.536

High

398409

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

5

High-throughput

0.536

High

398414

NPS3A
Protein NipSnap homolog 3A

1

1

High-throughput

0.536

High

398338

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

398325

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

398354

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

398388

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.513

High

398390

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

398397

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.513

High

398399

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

398412

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.513

High

398416

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

398417

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

398423

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

398424

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

398326

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

3

High-throughput

0.489

High

398373

PAF1
RNA polymerase II-associated factor 1 homolog

1

2

High-throughput

0.489

High

398391

RT24
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.489

High

398393

O52B2
Olfactory receptor 52B2

1

1

High-throughput

0.489

High

119082

LEG9
Galectin-9

1

2

High-throughput

0.479

High

125083

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

Small-scale

0.479

High

165905

PER2
Period circadian protein homolog 2

1

3

Small-scale

0.479

High

267844

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

294258

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

301536

TRI37
E3 ubiquitin-protein ligase TRIM37

1

4

High-throughput

0.479

High

322067

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

385913

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

398319

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

398322

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.479

High

398323

ARF4
ADP-ribosylation factor 4

1

3

High-throughput

0.479

High

398327

PML
Protein PML

1

3

High-throughput

0.479

High

398332

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

398333

EPS15
Epidermal growth factor receptor substrate 15

1

1

High-throughput

0.479

High

398334

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

16

High-throughput

0.479

High

398340

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

Small-scale

0.479

High

398341

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

1

Small-scale

0.479

High

398343

RBX1
E3 ubiquitin-protein ligase RBX1

1

3

High-throughput

0.479

High

398344

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

16

High-throughput

0.479

High

398352

HDAC1
Histone deacetylase 1

1

5

High-throughput

0.479

High

398355

RBBP7
Histone-binding protein RBBP7

1

18

High-throughput

0.479

High

398356

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

398359

DCAF6
DDB1- and CUL4-associated factor 6

1

20

High-throughput

0.479

High

398361

DCA12
DDB1- and CUL4-associated factor 12

1

2

High-throughput

0.479

High

398362

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.479

High

398364

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

398368

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.479

High

398372

WDTC1
WD and tetratricopeptide repeats protein 1

1

20

High-throughput

0.479

High

398376

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

398377

COP1
E3 ubiquitin-protein ligase COP1

1

20

High-throughput

0.479

High

398382

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

1

High-throughput

0.479

High

398383

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

398385

FBXW5
F-box/WD repeat-containing protein 5

1

2

High-throughput

0.479

High

398392

BICD1
Protein bicaudal D homolog 1

1

2

High-throughput

0.479

High

398395

RUFY1
RUN and FYVE domain-containing protein 1

1

2

High-throughput

0.479

High

398398

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

1

15

High-throughput

0.479

High

398406

DCA13
DDB1- and CUL4-associated factor 13

1

15

High-throughput

0.479

High

398410

WSB2
WD repeat and SOCS box-containing protein 2

1

18

High-throughput

0.479

High

398415

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

398419

DCTN4
Dynactin subunit 4

1

1

High-throughput

0.479

High

398422

FBW1A
F-box/WD repeat-containing protein 1A

1

17

High-throughput

0.479

High

398321

TPR
Nucleoprotein TPR

1

2

High-throughput

0.470

High

398413

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.460

High

398384

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.458

High

398402

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

0

High-throughput

0.458

High

398324

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

High-throughput

0.445

High

398347

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.445

High

398369

TLK2
Serine/threonine-protein kinase tousled-like 2

1

2

High-throughput

0.445

High

398346

CSK2B
Casein kinase II subunit beta

1

0

Small-scale

0.438

High

231962

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.437

High

329233

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

345679

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

398329

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

398331

TRI23
E3 ubiquitin-protein ligase TRIM23

1

7

High-throughput

0.437

High

398336

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

398342

WDR5
WD repeat-containing protein 5

1

16

High-throughput

0.437

High

398345

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.437

High

398349

TLE2
Transducin-like enhancer protein 2

1

17

High-throughput

0.437

High

398357

ISX
Intestine-specific homeobox

1

2

High-throughput

0.437

High

398358

SMU1
WD40 repeat-containing protein SMU1

1

20

High-throughput

0.437

High

398360

DCA10
DDB1- and CUL4-associated factor 10

1

20

High-throughput

0.437

High

398365

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

398366

DET1
DET1 homolog

1

3

High-throughput

0.437

High

398367

WDR53
WD repeat-containing protein 53

1

16

High-throughput

0.437

High

398370

HOOK3
Protein Hook homolog 3

1

5

High-throughput

0.437

High

398375

ARL10
ADP-ribosylation factor-like protein 10

1

6

High-throughput

0.437

High

398379

POC1B
POC1 centriolar protein homolog B

1

18

High-throughput

0.437

High

398380

DCAF4
DDB1- and CUL4-associated factor 4

1

3

High-throughput

0.437

High

398381

PHIP
PH-interacting protein

1

16

High-throughput

0.437

High

398386

PF21A
PHD finger protein 21A

1

3

High-throughput

0.437

High

398401

SPRTN
DNA-dependent metalloprotease SPRTN

1

2

High-throughput

0.437

High

398404

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.437

High

398407

NLE1
Notchless protein homolog 1

1

11

High-throughput

0.437

High

398408

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

398411

VSX1
Visual system homeobox 1

1

2

High-throughput

0.437

High

398418

HOOK1
Protein Hook homolog 1

1

5

High-throughput

0.437

High

398420

RCOR1
REST corepressor 1

1

3

High-throughput

0.437

High

398425

ARL5A
ADP-ribosylation factor-like protein 5A

1

8

High-throughput

0.437

High

64044

AQ12B
Aquaporin-12B

1

0

High-throughput

0.279

Low

269288

SG2A1
Mammaglobin-B

1

0

High-throughput

0.279

Low

398328

LCN1
Lipocalin-1

1

0

High-throughput

0.279

Low

398371

AMZ2
Archaemetzincin-2

1

0

High-throughput

0.279

Low

398378

FA81A
Protein FAM81A

1

0

High-throughput

0.279

Low

398387

TRI43
Tripartite motif-containing protein 43

1

0

High-throughput

0.279

Low

398396

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

1

0

High-throughput

0.279

Low

398400

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low

398335

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.261

Low

159318

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

271721

PRDM1
PR domain zinc finger protein 1

1

0

High-throughput

0.249

Low

398374

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.249

Low

398421

LHX6
LIM/homeobox protein Lhx6

1

0

High-throughput

0.249

Low

398339

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024