Protein: PTN13
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)

Gene: PTN13, PTPN13
Organism: Homo sapiens
Interactions: 182
UniProt ID: Q12923

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0001933 - negative regulation of protein phosphorylation
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1020197

RPGF6
Rap guanine nucleotide exchange factor 6

2

9

Small-scale

0.799

High

839889

PDLI4
PDZ and LIM domain protein 4

1

18

Small-scale

0.756

High

890637

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

6

Small-scale

0.754

High

915636

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

234509

DSCAM
Cell adhesion molecule DSCAM

1

14

High-throughput

0.698

High

1020184

STXB4
Syntaxin-binding protein 4

1

18

High-throughput

0.691

High

639737

IKBA
NF-kappa-B inhibitor alpha

4

20

Small-scale

0.680

High

632262

TNR6
Tumor necrosis factor receptor superfamily member 6

4

13

Small-scale

0.676

High

981964

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

1020164

TRIP6
Thyroid receptor-interacting protein 6

2

17

Small-scale

0.656

High

500962

GHR
Growth hormone receptor

1

20

Small-scale

0.647

High

1020219

PKHA1
Pleckstrin homology domain-containing family A member 1

2

12

Small-scale

0.646

High

683305

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.635

High

904503

1433G
14-3-3 protein gamma

2

20

High-throughput

0.635

High

909498

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.635

High

926984

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.635

High

782029

RGS2
Regulator of G-protein signaling 2

2

1

High-throughput

0.628

High

120411

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

196436

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

5

High-throughput

0.618

High

230867

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

7

High-throughput

0.618

High

318119

DIRA3
GTP-binding protein Di-Ras3

1

15

High-throughput

0.618

High

338350

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

350121

RASK
GTPase KRas

1

20

High-throughput

0.618

High

384744

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

411696

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.618

High

433729

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

434182

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.618

High

436277

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

507970

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

564499

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

577018

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

18

High-throughput

0.618

High

600564

EPHA1
Ephrin type-A receptor 1

1

20

High-throughput

0.618

High

665228

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

665393

EPHA3
Ephrin type-A receptor 3

1

20

High-throughput

0.618

High

665589

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.618

High

666588

LTK
Leukocyte tyrosine kinase receptor

1

20

High-throughput

0.618

High

844899

RAB7A
Ras-related protein Rab-7a

1

15

High-throughput

0.618

High

852454

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

872431

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.618

High

872638

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.618

High

876371

AFAD
Afadin

1

20

High-throughput

0.618

High

892339

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

893945

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

900421

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901140

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

925236

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1020162

RAB35
Ras-related protein Rab-35

1

19

High-throughput

0.618

High

1020163

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.618

High

1020165

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1020166

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.618

High

1020168

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.618

High

1020176

SPD2A
SH3 and PX domain-containing protein 2A

1

8

High-throughput

0.618

High

1020180

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.618

High

1020186

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1020191

KSR1
Kinase suppressor of Ras 1

1

20

High-throughput

0.618

High

1020198

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.618

High

1020199

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1020215

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1020220

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1020222

E41LA
Band 4.1-like protein 4A

1

18

High-throughput

0.618

High

1020230

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

12

High-throughput

0.618

High

1020241

RPGF2
Rap guanine nucleotide exchange factor 2

1

9

High-throughput

0.618

High

283103

DFFB
DNA fragmentation factor subunit beta

2

0

High-throughput

0.602

High

1020167

PKN2
Serine/threonine-protein kinase N2

1

12

Small-scale

0.592

High

325709

LATS1
Serine/threonine-protein kinase LATS1

2

13

High-throughput

0.584

High

506991

LAMP1
Lysosome-associated membrane glycoprotein 1

2

15

High-throughput

0.584

High

1020181

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

10

Small-scale

0.575

High

369500

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1020212

PDC10
Programmed cell death protein 10

1

0

Small-scale

0.568

High

646848

1433T
14-3-3 protein theta

1

20

High-throughput

0.554

High

71108

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

2

High-throughput

0.536

High

871546

HSP72
Heat shock-related 70 kDa protein 2

1

6

High-throughput

0.536

High

1020161

RPGF1
Rap guanine nucleotide exchange factor 1

1

9

High-throughput

0.536

High

1020183

TRI72
Tripartite motif-containing protein 72

1

5

High-throughput

0.536

High

1020203

ARRD3
Arrestin domain-containing protein 3

1

7

High-throughput

0.536

High

1020217

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1020231

STK26
Serine/threonine-protein kinase 26

1

16

High-throughput

0.536

High

1020243

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

6

High-throughput

0.536

High

1020218

PKHA2
Pleckstrin homology domain-containing family A member 2

1

10

Small-scale

0.527

High

787904

EPS15
Epidermal growth factor receptor substrate 15

1

12

Small-scale

0.516

High

1020225

LATS2
Serine/threonine-protein kinase LATS2

1

15

High-throughput

0.515

High

63645

RASFA
Ras association domain-containing protein 10

1

0

High-throughput

0.513

High

1020175

EFMT2
EEF1A lysine methyltransferase 2

1

0

High-throughput

0.513

High

815864

MTR1A
Melatonin receptor type 1A

1

8

High-throughput

0.508

High

131566

STK25
Serine/threonine-protein kinase 25

1

13

Small-scale

0.501

High

626113

APC
Adenomatous polyposis coli protein

1

11

Small-scale

0.501

High

714732

CRFR1
Corticotropin-releasing factor receptor 1

1

2

Small-scale

0.501

High

717037

CTNB1
Catenin beta-1

1

20

Small-scale

0.501

High

815676

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

2

Small-scale

0.501

High

957827

EFNB1
Ephrin-B1

1

3

Small-scale

0.501

High

1020174

RHG29
Rho GTPase-activating protein 29

1

9

Small-scale

0.501

High

321284

TBCD8
TBC1 domain family member 8

1

1

High-throughput

0.489

High

661248

S10A2
Protein S100-A2

1

4

High-throughput

0.489

High

1020194

ZCH10
Zinc finger CCHC domain-containing protein 10

1

5

High-throughput

0.489

High

1020209

TCPQM
T-complex protein 1 subunit theta-like 2

1

5

High-throughput

0.489

High

212815

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

232131

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.479

High

237207

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.479

High

244361

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.479

High

253346

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

10

High-throughput

0.479

High

264300

GGYF1
GRB10-interacting GYF protein 1

1

4

High-throughput

0.479

High

279532

FLOT1
Flotillin-1

1

14

High-throughput

0.479

High

305432

ZFPL1
Zinc finger protein-like 1

1

6

High-throughput

0.479

High

322542

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

7

High-throughput

0.479

High

331798

NSD2
Histone-lysine N-methyltransferase NSD2

1

2

Small-scale

0.479

High

374139

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

455377

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.479

High

552599

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

567033

CXA1
Gap junction alpha-1 protein

1

15

High-throughput

0.479

High

575410

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

598468

NF1
Neurofibromin

1

9

High-throughput

0.479

High

647882

MARK3
MAP/microtubule affinity-regulating kinase 3

1

4

Small-scale

0.479

High

651072

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

670005

MARCS
Myristoylated alanine-rich C-kinase substrate

1

11

High-throughput

0.479

High

684003

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

716666

CTNA1
Catenin alpha-1

1

2

Small-scale

0.479

High

720339

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

779320

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

793292

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.479

High

808559

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

835350

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.479

High

835708

GSK3B
Glycogen synthase kinase-3 beta

1

11

High-throughput

0.479

High

921542

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.479

High

940410

CXAR
Coxsackievirus and adenovirus receptor

1

17

High-throughput

0.479

High

971724

IRF8
Interferon regulatory factor 8

1

4

Small-scale

0.479

High

974786

CAV1
Caveolin-1

1

12

High-throughput

0.479

High

1020157

SQSTM
Sequestosome-1

1

4

Small-scale

0.479

High

1020159

HDAC1
Histone deacetylase 1

1

5

High-throughput

0.479

High

1020160

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1020169

OCLN
Occludin

1

9

High-throughput

0.479

High

1020171

AR13B
ADP-ribosylation factor-like protein 13B

1

20

High-throughput

0.479

High

1020172

AMOT
Angiomotin

1

20

High-throughput

0.479

High

1020173

MIDN
Midnolin

1

4

High-throughput

0.479

High

1020177

DEN4C
DENN domain-containing protein 4C

1

6

High-throughput

0.479

High

1020178

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.479

High

1020179

RNF43
E3 ubiquitin-protein ligase RNF43

1

20

High-throughput

0.479

High

1020182

GGYF2
GRB10-interacting GYF protein 2

1

15

High-throughput

0.479

High

1020187

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1020189

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

9

High-throughput

0.479

High

1020190

MIB1
E3 ubiquitin-protein ligase MIB1

1

16

High-throughput

0.479

High

1020192

CXD3
Gap junction delta-3 protein

1

15

High-throughput

0.479

High

1020193

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1020195

DEN1A
DENN domain-containing protein 1A

1

7

High-throughput

0.479

High

1020200

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1020201

GOGA1
Golgin subfamily A member 1

1

5

High-throughput

0.479

High

1020202

CK052
Uncharacterized protein C11orf52

1

8

High-throughput

0.479

High

1020204

PF21A
PHD finger protein 21A

1

4

High-throughput

0.479

High

1020208

FMNL2
Formin-like protein 2

1

6

High-throughput

0.479

High

1020211

RTKN
Rhotekin

1

1

High-throughput

0.479

High

1020213

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1020214

DNJC5
DnaJ homolog subfamily C member 5

1

9

High-throughput

0.479

High

1020216

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1020223

KI13B
Kinesin-like protein KIF13B

1

10

High-throughput

0.479

High

1020226

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

4

High-throughput

0.479

High

1020228

ARL8B
ADP-ribosylation factor-like protein 8B

1

16

High-throughput

0.479

High

1020229

ARL15
ADP-ribosylation factor-like protein 15

1

20

High-throughput

0.479

High

1020232

CING
Cingulin

1

6

High-throughput

0.479

High

1020233

FBW1B
F-box/WD repeat-containing protein 11

1

4

High-throughput

0.479

High

1020235

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

1020236

ZBT21
Zinc finger and BTB domain-containing protein 21

1

1

High-throughput

0.479

High

1020237

PPM1H
Protein phosphatase 1H

1

2

High-throughput

0.479

High

1020238

NINL
Ninein-like protein

1

4

High-throughput

0.479

High

1020239

GIT1
ARF GTPase-activating protein GIT1

1

10

Small-scale

0.479

High

1020240

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.479

High

1020242

KCTD3
BTB/POZ domain-containing protein KCTD3

1

6

High-throughput

0.479

High

673574

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.458

High

1020210

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.458

High

1020234

FBXL2
F-box/LRR-repeat protein 2

1

0

Small-scale

0.458

High

1020244

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

Small-scale

0.458

High

217873

PRKY
Putative serine/threonine-protein kinase PRKY

1

9

High-throughput

0.445

High

1020158

TBB3
Tubulin beta-3 chain

1

6

High-throughput

0.445

High

1020185

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.445

High

1020227

RN146
E3 ubiquitin-protein ligase RNF146

1

1

Small-scale

0.445

High

1020224

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

132464

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

3

High-throughput

0.437

High

1020188

TMM17
Transmembrane protein 17

1

4

High-throughput

0.437

High

1020196

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

9

High-throughput

0.437

High

1020221

TANC2
Protein TANC2

1

10

High-throughput

0.437

High

1020207

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.426

High

1020205

ENTR1
Endosome-associated-trafficking regulator 1

2

0

Small-scale

0.305

High

1020170

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1020206

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024