Protein: ARC
Activity-regulated cytoskeleton-associated protein (hArc) (Activity-regulated gene 3.1 protein homolog) (ARC/ARG3.1) (Arg3.1)

Gene: ARC
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q7LC44

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0003729 - mRNA binding
GO:0005198 - structural molecule activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1273193

SH24A
SH2 domain-containing protein 4A

2

1

High-throughput

0.606

High

597897

FER
Tyrosine-protein kinase Fer

2

0

High-throughput

0.602

High

702134

ITPI2
Protein ITPRID2

2

0

High-throughput

0.602

High

1211691

FA83B
Protein FAM83B

2

0

High-throughput

0.602

High

1273190

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

2

0

High-throughput

0.602

High

1273195

NDE1
Nuclear distribution protein nudE homolog 1

2

0

High-throughput

0.602

High

1273194

RN216
E3 ubiquitin-protein ligase RNF216

2

1

Small-scale

0.584

High

682533

S100P
Protein S100-P

2

0

High-throughput

0.580

High

1157704

CSRP2
Cysteine and glycine-rich protein 2

2

0

High-throughput

0.580

High

375657

RASK
GTPase KRas

2

0

High-throughput

0.559

High

618059

K1C15
Keratin, type I cytoskeletal 15

1

0

High-throughput

0.518

High

1179805

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.513

High

1273191

RIN2
Ras and Rab interactor 2

1

0

High-throughput

0.513

High

1050464

UBE3A
Ubiquitin-protein ligase E3A

1

0

Small-scale

0.480

High

1273192

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

0

Small-scale

0.480

High

363485

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

463996

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

1

High-throughput

0.479

High

939202

SUMO3
Small ubiquitin-related modifier 3

1

3

Small-scale

0.479

High

964344

SUMO2
Small ubiquitin-related modifier 2

1

3

Small-scale

0.479

High

991354

SUMO1
Small ubiquitin-related modifier 1

1

3

Small-scale

0.479

High

1006080

DLG4
Disks large homolog 4

1

2

Small-scale

0.479

High

891645

GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

0.458

High

1273196

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

Small-scale

0.458

High

351417

TBX18
T-box transcription factor TBX18

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025