Protein: CYPD
Peptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (Cyclophilin D) (Cyclosporin-sensitive proline rotamase 5) (Rotamase D)

Gene: CYPD, CPR5
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P35176

Gene Ontology (top 5):
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

745554

NGR1
Negative growth regulatory protein NGR1

1

2

High-throughput

0.665

High

762932

GET3
ATPase GET3

2

2

High-throughput

0.590

High

736481

MDHP
Malate dehydrogenase, peroxisomal

1

5

High-throughput

0.515

High

762911

MET10
Sulfite reductase [NADPH] flavoprotein component

1

2

High-throughput

0.515

High

762907

YHP7
Uncharacterized protein YHR097C

1

0

High-throughput

0.493

High

762908

ADY1
Prospore formation at selected spindle poles protein 1

1

0

High-throughput

0.493

High

762927

GNTK
Probable gluconokinase

1

0

High-throughput

0.493

High

585479

KCY
Uridylate kinase

1

1

High-throughput

0.479

High

592157

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.479

High

610123

PDI
Protein disulfide-isomerase

1

14

High-throughput

0.479

High

627782

PYRC
Dihydroorotase

1

1

High-throughput

0.479

High

672007

MSH3
DNA mismatch repair protein MSH3

1

3

High-throughput

0.479

High

704865

KIP1
Kinesin-like protein KIP1

1

2

High-throughput

0.479

High

737515

EUG1
Protein disulfide-isomerase EUG1

1

15

High-throughput

0.479

High

748325

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.479

High

762900

AKL1
Serine/threonine-protein kinase AKL1

1

1

High-throughput

0.479

High

762903

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.479

High

762904

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

3

High-throughput

0.479

High

762909

MPT5
Suppressor protein MPT5

1

3

High-throughput

0.479

High

762914

IMB4
Importin subunit beta-4

1

2

High-throughput

0.479

High

762916

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.479

High

762925

RIA1
Ribosome assembly protein 1

1

5

High-throughput

0.479

High

762926

YNN4
Uncharacterized protein YNL134C

1

2

High-throughput

0.479

High

762928

RGC1
Regulator of the glycerol channel 1

1

1

High-throughput

0.479

High

762931

AB140
tRNA(Thr)

1

1

High-throughput

0.479

High

762933

INP53
Polyphosphatidylinositol phosphatase INP53

1

1

High-throughput

0.479

High

762934

RDL1
Thiosulfate:glutathione sulfurtransferase

1

1

High-throughput

0.479

High

510960

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.458

High

576052

AROF
Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

1

0

High-throughput

0.458

High

721828

XPO1
Exportin-1

1

0

High-throughput

0.458

High

723596

MLS1
Malate synthase 1

1

0

High-throughput

0.458

High

762902

ECM21
Protein ECM21

1

0

High-throughput

0.458

High

762906

SDO1L
Restriction of telomere capping protein 3

1

0

High-throughput

0.458

High

762921

YJF5
LOG family protein YJL055W

1

0

High-throughput

0.458

High

762923

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

762929

CND3
Condensin complex subunit 3

1

0

High-throughput

0.458

High

544387

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

360963

CCPR
Cytochrome c peroxidase, mitochondrial

1

1

High-throughput

0.437

High

603444

VATA
V-type proton ATPase catalytic subunit A

1

8

High-throughput

0.437

High

706720

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

762901

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

7

High-throughput

0.437

High

762910

IFH1
Protein IFH1

1

3

High-throughput

0.437

High

762912

GDI1
Rab GDP-dissociation inhibitor

1

1

High-throughput

0.437

High

762915

RIC1
Guanine nucleotide exchange factor subunit RIC1

1

1

High-throughput

0.437

High

762918

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.437

High

762920

SUM1
Suppressor of mar1-1 protein

1

1

High-throughput

0.437

High

762922

MTR4
ATP-dependent RNA helicase DOB1

1

4

High-throughput

0.437

High

762905

YHA8
Uncharacterized transporter YHL008C

1

0

High-throughput

0.269

Low

762913

RSM18
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.269

Low

762917

YRB2
Ran-specific GTPase-activating protein 2

1

0

High-throughput

0.269

Low

762924

SOK2
Protein SOK2

1

0

High-throughput

0.269

Low

481875

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

762898

APE3
Aminopeptidase Y

1

0

High-throughput

0.249

Low

762899

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

762919

MIL1
Probable lipase MIL1

1

0

High-throughput

0.249

Low

762930

LEC1
PX domain-containing protein LEC1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025