Protein: CDC3
Cell division control protein 3

Gene: CDC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 176
UniProt ID: P32457

Gene Ontology (top 5):
GO:0000144 - cellular bud neck septin ring
GO:0000281 - mitotic cytokinesis
GO:0000920 - septum digestion after cytokinesis
GO:0000921 - septin ring assembly
GO:0001400 - mating projection base

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

736937

CDC12
Cell division control protein 12

18

20

Small-scale

0.988

High

736936

CDC11
Cell division control protein 11

16

20

Small-scale

0.988

High

672222

CDC10
Cell division control protein 10

15

19

Small-scale

0.987

High

737055

SHS1
Seventh homolog of septin 1

9

20

Small-scale

0.974

High

736992

SPR3
Sporulation-regulated protein 3

2

20

Small-scale

0.768

High

736935

CDC3
Cell division control protein 3

2

20

Small-scale

0.737

High

737062

GIN4
Serine/threonine-protein kinase GIN4

5

5

Small-scale

0.722

High

737015

BNI5
Bud neck protein 5

4

0

Small-scale

0.666

High

673685

KCC4
Probable serine/threonine-protein kinase KCC4

3

6

Small-scale

0.658

High

737038

SIZ1
E3 SUMO-protein ligase SIZ1

3

1

Small-scale

0.653

High

736950

HSL1
Probable serine/threonine-protein kinase HSL1

2

5

Small-scale

0.601

High

737063

SMT3
Ubiquitin-like protein SMT3

2

0

Small-scale

0.569

High

646341

RAD53
Serine/threonine-protein kinase RAD53

2

0

Small-scale

0.559

High

737008

CLA4
Serine/threonine-protein kinase CLA4

2

2

Small-scale

0.550

High

737031

STE20
Serine/threonine-protein kinase STE20

2

3

Small-scale

0.550

High

737009

UBC9
SUMO-conjugating enzyme UBC9

2

6

Small-scale

0.543

High

736958

BOI1
BEM1-interacting protein 1

1

4

High-throughput

0.541

High

737044

CYK2
Cytokinesis protein 2

1

2

Small-scale

0.541

High

736999

BNA3
Probable kynurenine--oxoglutarate transaminase BNA3

2

1

High-throughput

0.537

High

736959

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

4

High-throughput

0.536

High

737067

CMR1
DNA damage-binding protein CMR1

2

2

High-throughput

0.533

High

686881

BUB2
Mitotic check point protein BUB2

1

1

Small-scale

0.523

High

523355

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.521

High

544158

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.504

High

364409

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.501

High

656719

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

736991

BNI1
Protein BNI1

1

4

High-throughput

0.501

High

660214

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.489

High

736951

SPT7
SAGA complex subunit SPT7

1

4

High-throughput

0.489

High

737029

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.489

High

736983

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.486

High

737061

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

Small-scale

0.481

High

602036

KAR3
Kinesin-like protein KAR3

1

2

High-throughput

0.481

High

735602

SMY1
Kinesin-related protein SMY1

1

3

High-throughput

0.481

High

736962

EXO84
Exocyst complex component EXO84

1

1

High-throughput

0.481

High

736987

BNR1
BNI1-related protein 1

1

4

High-throughput

0.481

High

737021

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

1

High-throughput

0.481

High

736940

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.479

High

736966

GIC1
GTPase-interacting component 1

1

1

Small-scale

0.479

High

737005

BUD4
Bud site selection protein 4

1

1

High-throughput

0.479

High

737052

GIC2
GTPase-interacting component 2

1

1

Small-scale

0.479

High

670463

SIS1
Protein SIS1

1

5

High-throughput

0.470

High

736963

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.470

High

154353

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.460

High

733625

MGM1
Dynamin-like GTPase MGM1, mitochondrial

1

0

High-throughput

0.460

High

736945

SPC29
Spindle pole component 29

1

0

High-throughput

0.460

High

736957

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.460

High

736969

BZZ1
Protein BZZ1

1

0

High-throughput

0.460

High

736970

KEL1
Kelch repeat-containing protein 1

1

0

High-throughput

0.460

High

736997

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.460

High

736998

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.460

High

737017

NIS1
Protein NIS1

1

0

Small-scale

0.460

High

737048

SEC10
Exocyst complex component SEC10

1

0

High-throughput

0.460

High

737064

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

737068

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.460

High

736979

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

737057

ESA1
Histone acetyltransferase ESA1

1

2

Small-scale

0.457

High

367719

ENO1
Enolase 1

1

1

High-throughput

0.457

High

646008

KIN3
Serine/threonine-protein kinase KIN3

1

1

High-throughput

0.439

High

725907

PSK1
Serine/threonine-protein kinase PSK1

1

3

High-throughput

0.439

High

736943

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.439

High

736946

NIP80
Protein NIP100

1

7

High-throughput

0.439

High

736948

NUF2
Kinetochore protein NUF2

1

4

High-throughput

0.439

High

736949

CASP
Protein CASP

1

3

High-throughput

0.439

High

736968

LAM4
Membrane-anchored lipid-binding protein LAM4

1

1

High-throughput

0.439

High

736972

KOG1
Target of rapamycin complex 1 subunit KOG1

1

10

High-throughput

0.439

High

736981

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.439

High

736985

ATAD2
ATPase histone chaperone YTA7

1

6

High-throughput

0.439

High

736990

MAD1
Spindle assembly checkpoint component MAD1

1

7

High-throughput

0.439

High

737000

SNX4
Sorting nexin-4

1

2

High-throughput

0.439

High

737010

ATG1
Serine/threonine-protein kinase ATG1

1

1

High-throughput

0.439

High

737012

PRS10
26S proteasome subunit RPT4

1

8

High-throughput

0.439

High

737014

IPI3
Pre-rRNA-processing protein IPI3

1

3

High-throughput

0.439

High

737023

MDM1
Structural protein MDM1

1

1

High-throughput

0.439

High

737028

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

1

High-throughput

0.439

High

737030

VPS60
Vacuolar protein-sorting-associated protein 60

1

1

High-throughput

0.439

High

737036

SNX41
Sorting nexin-41

1

2

High-throughput

0.439

High

737053

YSP2
Membrane-anchored lipid-binding protein YSP2

1

1

High-throughput

0.439

High

737058

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

1

High-throughput

0.439

High

737069

VPS5
Vacuolar protein sorting-associated protein 5

1

2

High-throughput

0.439

High

736960

ATG8
Autophagy-related protein 8

1

4

High-throughput

0.437

High

736977

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

736978

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.437

High

737018

H3
Histone H3

1

1

High-throughput

0.437

High

737035

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

737066

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

670233

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.426

High

736938

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

737013

BNI4
Protein BNI4

1

0

High-throughput

0.426

High

736967

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.407

High

737051

NDE1
Nuclear distribution protein nudE homolog 1

2

0

High-throughput

0.310

High

579035

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.310

High

737040

HSP31
Glutathione-independent glyoxalase HSP31

2

0

High-throughput

0.307

High

736989

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

737056

ULS1
ATP-dependent helicase ULS1

2

0

Small-scale

0.304

High

566493

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

High-throughput

0.279

Low

591946

THRC
Threonine synthase

1

0

High-throughput

0.279

Low

583756

SEC11
Signal peptidase complex catalytic subunit SEC11

1

0

High-throughput

0.269

Low

737004

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

0

High-throughput

0.269

Low

737024

YKZ1
Uncharacterized protein YKR011C

1

0

High-throughput

0.269

Low

737050

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.269

Low

517950

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

737025

ULP1
Ubiquitin-like-specific protease 1

1

0

Small-scale

0.261

Low

399354

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

0

High-throughput

0.261

Low

405056

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

432300

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.261

Low

439107

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low

439287

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.261

Low

555035

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

572537

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.261

Low

592092

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.261

Low

737032

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.261

Low

438272

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.251

Low

455557

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.251

Low

639482

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

646218

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.251

Low

673622

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.251

Low

677741

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

736939

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

736941

VAM7
Vacuolar morphogenesis protein 7

1

0

High-throughput

0.251

Low

736944

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.251

Low

736947

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

736953

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.251

Low

736954

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

736956

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

736961

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

736964

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.251

Low

736971

TDA11
Topoisomerase I damage affected protein 11

1

0

High-throughput

0.251

Low

736973

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

736974

SKN7
Transcription factor SKN7

1

0

High-throughput

0.251

Low

736975

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.251

Low

736976

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.251

Low

736980

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

736982

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.251

Low

736984

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.251

Low

736986

RAD26
DNA repair and recombination protein RAD26

1

0

High-throughput

0.251

Low

736993

GCN20
Protein GCN20

1

0

High-throughput

0.251

Low

736994

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

736995

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

736996

CHA4
Activatory protein CHA4

1

0

High-throughput

0.251

Low

737001

VPS53
Vacuolar protein sorting-associated protein 53

1

0

High-throughput

0.251

Low

737002

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.251

Low

737003

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.251

Low

737006

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

737007

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.251

Low

737011

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

737016

AF9
Protein AF-9 homolog

1

0

High-throughput

0.251

Low

737019

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.251

Low

737020

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

737022

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.251

Low

737026

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.251

Low

737027

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.251

Low

737033

INP1
Inheritance of peroxisomes protein 1

1

0

Small-scale

0.251

Low

737034

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

737037

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

737039

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.251

Low

737041

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

737042

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.251

Low

737043

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

737045

ENT2
Epsin-2

1

0

High-throughput

0.251

Low

737046

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.251

Low

737047

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.251

Low

737049

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit CNL1

1

0

High-throughput

0.251

Low

737054

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.251

Low

737059

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.251

Low

737065

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

737070

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

434923

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

706492

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

736942

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

736952

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

736955

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.249

Low

737060

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

736965

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.232

Low

736988

AIR1
Protein AIR1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025