Protein: PFLB
Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1)

Gene: PFLB
Organism: Escherichia coli K-12
Interactions: 64
UniProt ID: P09373

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006006 - glucose metabolic process
GO:0008861 - formate C-acetyltransferase activity
GO:0016020 - membrane
GO:0044814 - glycolytic fermentation via PFL pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

480619

GRCA
Autonomous glycyl radical cofactor

3

2

High-throughput

0.848

High

480573

TPIS
Triosephosphate isomerase

3

1

High-throughput

0.672

High

480595

KPYK2
Pyruvate kinase II

2

1

High-throughput

0.639

High

480585

YFCZ
UPF0381 protein YfcZ

2

2

High-throughput

0.618

High

480568

PFLB
Formate acetyltransferase 1

1

2

High-throughput

0.618

High

480601

PEPT
Peptidase T

2

0

High-throughput

0.612

High

480574

SYK2
Lysine--tRNA ligase, heat inducible

2

1

High-throughput

0.588

High

480592

HELD
DNA helicase IV

2

0

High-throughput

0.585

High

480590

IBPA
Small heat shock protein IbpA

2

0

High-throughput

0.563

High

480572

TIG
Trigger factor

1

1

High-throughput

0.536

High

480586

KPYK1
Pyruvate kinase I

1

1

High-throughput

0.536

High

480606

YIIS
UPF0381 protein YiiS

1

2

High-throughput

0.536

High

449941

FHUA
Ferrichrome outer membrane transporter/phage receptor

1

0

High-throughput

0.513

High

480578

YAJD
Putative HNH nuclease YajD

1

0

High-throughput

0.513

High

480594

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

480596

KITH
Thymidine kinase

1

0

High-throughput

0.513

High

480597

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.513

High

480599

GCST
Aminomethyltransferase

1

0

High-throughput

0.513

High

480603

LEUD
3-isopropylmalate dehydratase small subunit

1

0

High-throughput

0.513

High

480618

YDFZ
Putative selenoprotein YdfZ

1

0

High-throughput

0.513

High

480571

SUCC
Succinate--CoA ligase [ADP-forming] subunit beta

1

1

High-throughput

0.500

High

480582

EXBB
Biopolymer transport protein ExbB

1

1

High-throughput

0.500

High

480598

MAK
Fructokinase

1

1

High-throughput

0.500

High

480623

ECPB
Probable fimbrial chaperone EcpB

1

1

High-throughput

0.489

High

480616

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.484

High

480577

P5CR
Pyrroline-5-carboxylate reductase

1

1

High-throughput

0.479

High

480607

TKT2
Transketolase 2

1

1

High-throughput

0.479

High

480583

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.464

High

480584

SSPA
Stringent starvation protein A

1

0

High-throughput

0.464

High

437522

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

480569

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.458

High

480570

NAGB
Glucosamine-6-phosphate deaminase

1

0

High-throughput

0.458

High

480587

VIAA
Regulatory protein ViaA

1

0

High-throughput

0.458

High

480604

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.458

High

480608

NUOCD
NADH-quinone oxidoreductase subunit C/D

1

0

High-throughput

0.458

High

480613

INTB
Putative protein IntB

1

0

High-throughput

0.458

High

393839

PBPA
Penicillin-binding protein 1A

1

1

High-throughput

0.437

High

480575

BLC
Outer membrane lipoprotein Blc

1

1

High-throughput

0.437

High

480602

LHR
Lhr helicase/uracil glycosylase

1

1

High-throughput

0.437

High

480609

WBBK
Putative glycosyltransferase WbbK

1

1

High-throughput

0.437

High

480610

AG43
Antigen 43

1

1

High-throughput

0.437

High

480611

YJDJ
Uncharacterized protein YjdJ

1

1

High-throughput

0.437

High

480593

SRLR
Glucitol operon repressor

2

0

High-throughput

0.330

High

449895

CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme

2

0

High-throughput

0.318

High

480588

TSAE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE

2

0

High-throughput

0.307

High

480621

YDGK
Inner membrane protein YdgK

1

0

High-throughput

0.282

High

480576

FTSZ
Cell division protein FtsZ

1

0

High-throughput

0.279

Low

480581

CYOA
Cytochrome bo(3) ubiquinol oxidase subunit 2

1

0

High-throughput

0.279

Low

480591

RACC
Protein RacC

1

0

High-throughput

0.279

Low

480600

ROXA
Ribosomal protein uL16 3-hydroxylase

1

0

High-throughput

0.279

Low

480605

FIXB
Protein FixB

1

0

High-throughput

0.279

Low

480612

YJEJ
Uncharacterized protein YjeJ

1

0

High-throughput

0.279

Low

480614

YBII
Uncharacterized protein YbiI

1

0

High-throughput

0.279

Low

480615

DXR
1-deoxy-D-xylulose 5-phosphate reductoisomerase

1

0

High-throughput

0.279

Low

480620

YDFK
Cold shock protein YdfK

1

0

High-throughput

0.279

Low

480622

YBDM
Uncharacterized protein YbdM

1

0

High-throughput

0.279

Low

480624

GCS2
Putative glutamate--cysteine ligase 2

1

0

High-throughput

0.279

Low

480625

HSCC
Chaperone protein HscC

1

0

High-throughput

0.279

Low

480626

SUFD
Iron-sulfur cluster assembly protein SufD

1

0

High-throughput

0.279

Low

480580

ATMA
Magnesium-transporting ATPase, P-type 1

1

0

High-throughput

0.269

Low

480579

YCBJ
Uncharacterized protein YcbJ

1

0

High-throughput

0.249

Low

480589

RMF
Ribosome modulation factor

1

0

High-throughput

0.249

Low

480617

LOLB
Outer-membrane lipoprotein LolB

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025