Protein: DPO3A
DNA polymerase III subunit alpha (EC 2.7.7.7)

Gene: DPO3A, dnaE
Organism: Escherichia coli K-12
Interactions: 72
UniProt ID: P10443

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006261 - DNA-templated DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

445415

DPO3X
DNA polymerase III subunit tau

7

1

Small-scale

0.964

High

496358

DPO3B
Beta sliding clamp

5

4

Small-scale

0.928

High

395121

DPO3E
DNA polymerase III subunit epsilon

10

0

Small-scale

0.927

High

522205

HOLA
DNA polymerase III subunit delta

3

0

Small-scale

0.646

High

506253

EFTU1
Elongation factor Tu 1

2

1

High-throughput

0.611

High

522231

YBDL
Methionine aminotransferase

2

0

High-throughput

0.606

High

522201

ASNB
Asparagine synthetase B [glutamine-hydrolyzing]

2

0

High-throughput

0.585

High

492743

RL1
Large ribosomal subunit protein uL1

2

0

High-throughput

0.576

High

493491

RS16
Small ribosomal subunit protein bS16

2

0

High-throughput

0.576

High

497502

RL13
Large ribosomal subunit protein uL13

2

0

High-throughput

0.576

High

501231

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.576

High

501373

RS1
Small ribosomal subunit protein bS1

2

0

High-throughput

0.576

High

492513

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.563

High

495043

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.563

High

498558

HOLE
DNA polymerase III subunit theta

2

0

Small-scale

0.563

High

522206

HOLB
DNA polymerase III subunit delta'

1

2

High-throughput

0.561

High

522211

YEJF
Uncharacterized ABC transporter ATP-binding protein YejF

2

2

High-throughput

0.558

High

522207

HOLD
DNA polymerase III subunit psi

1

0

High-throughput

0.537

High

522208

HOLC
DNA polymerase III subunit chi

1

0

High-throughput

0.537

High

499114

DBHB
DNA-binding protein HU-beta

1

1

High-throughput

0.536

High

522195

BIOA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

1

1

High-throughput

0.536

High

522200

ARGD
Acetylornithine/succinyldiaminopimelate aminotransferase

1

1

High-throughput

0.536

High

368279

CYAA
Adenylate cyclase

1

0

High-throughput

0.513

High

493764

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

496956

PTA
Phosphate acetyltransferase

1

0

High-throughput

0.513

High

497020

DLDH
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.513

High

498855

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.513

High

500747

ODO1
2-oxoglutarate dehydrogenase E1 component

1

0

High-throughput

0.513

High

500757

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

1

0

High-throughput

0.513

High

500785

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

500997

RNK
Regulator of nucleoside diphosphate kinase

1

0

High-throughput

0.513

High

501551

SUCD
Succinate--CoA ligase [ADP-forming] subunit alpha

1

0

High-throughput

0.513

High

515959

CRFC
Clamp-binding protein CrfC

1

0

High-throughput

0.513

High

522196

METH
Methionine synthase

1

0

High-throughput

0.513

High

522197

FDHE
Protein FdhE

1

0

High-throughput

0.513

High

522198

HELD
DNA helicase IV

1

0

High-throughput

0.513

High

522216

USPG
Universal stress protein UP12

1

0

High-throughput

0.513

High

522218

IADA
Isoaspartyl dipeptidase

1

0

High-throughput

0.513

High

522219

YHAK
Pirin-like protein YhaK

1

0

High-throughput

0.513

High

522222

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

522227

TMCA
tRNA(Met) cytidine acetyltransferase TmcA

1

0

High-throughput

0.513

High

522233

BGLA
6-phospho-beta-glucosidase BglA

1

0

High-throughput

0.513

High

506322

EFTU2
Elongation factor Tu 2

1

1

High-throughput

0.500

High

522209

EVGS
Sensor protein EvgS

1

0

High-throughput

0.493

High

522199

RHSD
Protein RhsD

1

1

High-throughput

0.489

High

522203

FDNG
Formate dehydrogenase, nitrate-inducible, major subunit

1

1

High-throughput

0.489

High

522204

RHSE
Putative protein RhsE

1

1

High-throughput

0.489

High

522210

NIKD
Nickel import ATP-binding protein NikD

1

2

High-throughput

0.489

High

522213

DPPF
Dipeptide transport ATP-binding protein DppF

1

2

High-throughput

0.489

High

522230

YNFE
Putative dimethyl sulfoxide reductase chain YnfE

1

1

High-throughput

0.470

High

491122

DNAK
Chaperone protein DnaK

1

0

High-throughput

0.464

High

501036

SSPB
Stringent starvation protein B

1

0

High-throughput

0.464

High

522223

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

491969

NUSB
Transcription antitermination protein NusB

1

0

High-throughput

0.458

High

495092

TRMD
tRNA

1

0

High-throughput

0.458

High

498914

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

501523

SSB
Single-stranded DNA-binding protein

1

0

High-throughput

0.426

High

492041

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.279

Low

499859

PPID
Periplasmic chaperone PpiD

1

0

High-throughput

0.279

Low

522202

FEPC
Ferric enterobactin transport ATP-binding protein FepC

1

0

High-throughput

0.279

Low

522212

HRPB
ATP-dependent RNA helicase HrpB

1

0

High-throughput

0.279

Low

522214

BCSA
Cellulose synthase catalytic subunit [UDP-forming]

1

0

High-throughput

0.279

Low

522215

CAS3
CRISPR-associated endonuclease/helicase Cas3

1

0

High-throughput

0.279

Low

522217

MSCM
Miniconductance mechanosensitive channel MscM

1

0

High-throughput

0.279

Low

522220

ABPB
Anti-bacteriophage protein B

1

0

High-throughput

0.279

Low

522221

FLIJ
Flagellar FliJ protein

1

0

High-throughput

0.279

Low

522224

BLUF
Blue light- and temperature-regulated antirepressor BluF

1

0

High-throughput

0.279

Low

522225

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

1

0

High-throughput

0.279

Low

522226

CMOB
tRNA U34 carboxymethyltransferase

1

0

High-throughput

0.279

Low

522228

YAFZ
UPF0380 protein YafZ

1

0

High-throughput

0.279

Low

522229

YBDR
Uncharacterized zinc-type alcohol dehydrogenase-like protein YbdR

1

0

High-throughput

0.279

Low

522232

SSUD
Alkanesulfonate monooxygenase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025