Protein: TPIS
Triosephosphate isomerase (TIM) (TPI) (EC 5.3.1.1) (Triose-phosphate isomerase)

Gene: TPIS, tpiA
Organism: Escherichia coli K-12
Interactions: 31
UniProt ID: P0A858

Gene Ontology (top 5):
GO:0004807 - triose-phosphate isomerase activity
GO:0005829 - cytosol
GO:0006094 - gluconeogenesis
GO:0006096 - glycolytic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

495036

TPIS
Triosephosphate isomerase

2

6

High-throughput

0.743

High

480573

PFLB
Formate acetyltransferase 1

3

1

High-throughput

0.672

High

495048

PEPT
Peptidase T

2

0

High-throughput

0.596

High

494589

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.563

High

495037

SYK2
Lysine--tRNA ligase, heat inducible

2

0

High-throughput

0.563

High

495043

DPO3A
DNA polymerase III subunit alpha

2

0

High-throughput

0.563

High

495045

HELD
DNA helicase IV

2

0

High-throughput

0.563

High

495050

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.563

High

491989

PFKA
ATP-dependent 6-phosphofructokinase isozyme 1

1

1

High-throughput

0.536

High

489406

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

491590

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.513

High

492124

HSLV
ATP-dependent protease subunit HslV

1

0

High-throughput

0.513

High

495038

FUR
Ferric uptake regulation protein

1

0

High-throughput

0.513

High

495042

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.513

High

495044

FDHE
Protein FdhE

1

0

High-throughput

0.513

High

495047

WAAU
Putative lipopolysaccharide heptosyltransferase 4

1

0

High-throughput

0.513

High

495052

PTNAB
PTS system mannose-specific EIIAB component

1

0

High-throughput

0.513

High

495054

YNAE
Uncharacterized protein YnaE

1

1

High-throughput

0.489

High

495055

YDFK
Cold shock protein YdfK

1

1

High-throughput

0.489

High

495051

GRCA
Autonomous glycyl radical cofactor

1

1

High-throughput

0.484

High

491013

DNAK
Chaperone protein DnaK

1

0

High-throughput

0.464

High

492893

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.464

High

495041

ENTB
Enterobactin synthase component B

1

0

High-throughput

0.464

High

495039

THIO
Thioredoxin 1

1

3

Small-scale

0.445

High

495049

YIIQ
Uncharacterized protein YiiQ

1

0

High-throughput

0.279

Low

495056

YBER
Uncharacterized protein YbeR

1

0

High-throughput

0.279

Low

495046

PHNJ
Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase

1

0

High-throughput

0.269

Low

493687

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.253

Low

495040

HYPC
Hydrogenase maturation factor HypC

1

0

High-throughput

0.249

Low

495053

YBFL
Putative protein YbfL

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025