Protein: RLMN
Dual-specificity RNA methyltransferase RlmN (EC 2.1.1.192) (23S rRNA (adenine(2503)-C(2))-methyltransferase) (23S rRNA m2A2503 methyltransferase) (Ribosomal RNA large subunit methyltransferase N) (tRNA (adenine(37)-C(2))-methyltransferase) (tRNA m2A37 methyltransferase)

Gene: RLMN
Organism: Escherichia coli K-12
Interactions: 101
UniProt ID: P36979

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002935 - tRNA (adenine(37)-C2)-methyltransferase activity
GO:0005829 - cytosol
GO:0019843 - rRNA binding
GO:0030488 - tRNA methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

739440

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.663

High

462205

RS4
Small ribosomal subunit protein uS4

3

0

High-throughput

0.629

High

439478

PHOR
Phosphate regulon sensor protein PhoR

3

0

High-throughput

0.628

High

599080

SRMB
ATP-dependent RNA helicase SrmB

2

1

High-throughput

0.620

High

358411

RL15
Large ribosomal subunit protein uL15

2

0

High-throughput

0.613

High

393752

PNP
Polyribonucleotide nucleotidyltransferase

2

1

High-throughput

0.611

High

474178

EFTU1
Elongation factor Tu 1

2

2

High-throughput

0.611

High

534557

SELB
Selenocysteine-specific elongation factor

2

3

High-throughput

0.611

High

739445

RL3
Large ribosomal subunit protein uL3

2

0

High-throughput

0.602

High

459500

IF2
Translation initiation factor IF-2

2

5

High-throughput

0.588

High

463680

SYK1
Lysine--tRNA ligase

2

1

High-throughput

0.588

High

466444

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

1

High-throughput

0.588

High

468296

ELAB
Protein ElaB

2

1

High-throughput

0.588

High

739450

CLPB
Chaperone protein ClpB

2

1

High-throughput

0.588

High

460820

RL1
Large ribosomal subunit protein uL1

2

0

High-throughput

0.585

High

739444

RL2
Large ribosomal subunit protein uL2

2

0

High-throughput

0.585

High

356965

RS6
Small ribosomal subunit protein bS6

2

0

High-throughput

0.585

High

469235

RL17
Large ribosomal subunit protein bL17

2

0

High-throughput

0.585

High

488856

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.585

High

739453

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

2

0

High-throughput

0.585

High

458469

DAPF
Diaminopimelate epimerase

2

0

High-throughput

0.563

High

458576

EFG
Elongation factor G

2

0

High-throughput

0.563

High

459556

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

2

0

High-throughput

0.563

High

460587

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.563

High

460923

RL27
Large ribosomal subunit protein bL27

2

0

High-throughput

0.563

High

461024

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.563

High

461095

RL29
Large ribosomal subunit protein uL29

2

0

High-throughput

0.563

High

461593

RS18
Small ribosomal subunit protein bS18

2

0

High-throughput

0.563

High

463098

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.563

High

465159

DEAD
ATP-dependent RNA helicase DeaD

2

0

High-throughput

0.563

High

467089

HINT
Purine nucleoside phosphoramidase

2

0

High-throughput

0.563

High

467785

YIBL
Uncharacterized protein YibL

2

0

High-throughput

0.563

High

467828

YGAM
Uncharacterized protein YgaM

2

0

High-throughput

0.563

High

468502

GYRB
DNA gyrase subunit B

2

0

High-throughput

0.563

High

468536

SKP
Chaperone protein Skp

2

0

High-throughput

0.563

High

469151

SPOT
Bifunctional

2

0

High-throughput

0.563

High

469385

RS14
Small ribosomal subunit protein uS14

2

0

High-throughput

0.563

High

469695

YHBY
RNA-binding protein YhbY

2

0

High-throughput

0.563

High

421129

OMPC
Outer membrane porin C

1

1

High-throughput

0.561

High

442727

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.537

High

599049

RNR
Ribonuclease R

1

0

High-throughput

0.537

High

739441

RLMJ
Ribosomal RNA large subunit methyltransferase J

1

0

High-throughput

0.537

High

739442

RLUB
Ribosomal large subunit pseudouridine synthase B

1

0

High-throughput

0.537

High

357107

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

457856

CH60
Chaperonin GroEL

1

0

High-throughput

0.513

High

462370

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

465082

DLDH
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.513

High

468855

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

578962

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

599096

RNE
Ribonuclease E

1

0

High-throughput

0.513

High

676796

3PASE
Inorganic triphosphatase

1

0

High-throughput

0.513

High

474236

EFTU2
Elongation factor Tu 2

1

2

High-throughput

0.500

High

367499

PHOE
Outer membrane porin PhoE

1

1

High-throughput

0.489

High

463714

SYK2
Lysine--tRNA ligase, heat inducible

1

1

High-throughput

0.484

High

739449

RL5
Large ribosomal subunit protein uL5

1

1

High-throughput

0.484

High

460347

RECA
Protein RecA

1

0

High-throughput

0.464

High

460683

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

460892

RL20
Large ribosomal subunit protein bL20

1

0

High-throughput

0.464

High

461223

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

461316

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.464

High

462004

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.464

High

462797

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.464

High

463631

YEEX
UPF0265 protein YeeX

1

0

High-throughput

0.464

High

463896

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.464

High

464964

LON
Lon protease

1

0

High-throughput

0.464

High

465569

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

467126

DBHA
DNA-binding protein HU-alpha

1

0

High-throughput

0.464

High

467987

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.464

High

469294

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.464

High

469337

RL6
Large ribosomal subunit protein uL6

1

0

High-throughput

0.464

High

469657

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

469724

RL18
Large ribosomal subunit protein uL18

1

0

High-throughput

0.464

High

473821

GATY
D-tagatose-1,6-bisphosphate aldolase subunit GatY

1

0

High-throughput

0.464

High

483563

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

739446

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.464

High

739447

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

739448

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

461469

RS13
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

461694

RS20
Small ribosomal subunit protein bS20

1

0

High-throughput

0.458

High

739451

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

0

High-throughput

0.458

High

469440

RS1
Small ribosomal subunit protein bS1

1

1

High-throughput

0.442

High

421111

MALT
HTH-type transcriptional regulator MalT

2

0

High-throughput

0.330

High

367435

MELB
Melibiose permease

2

0

High-throughput

0.318

High

367502

MCP1
Methyl-accepting chemotaxis protein I

2

0

High-throughput

0.318

High

702453

NUPX
Putative nucleoside permease NupX

2

0

High-throughput

0.318

High

706833

NUOCD
NADH-quinone oxidoreductase subunit C/D

2

0

High-throughput

0.318

High

739443

HRPA
ATP-dependent RNA helicase HrpA

2

0

High-throughput

0.318

High

739452

WCAD
Putative colanic acid polymerase

2

0

High-throughput

0.318

High

739454

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

2

0

High-throughput

0.318

High

467416

CRA
Catabolite repressor/activator

2

0

High-throughput

0.307

High

464488

FTSZ
Cell division protein FtsZ

1

0

High-throughput

0.304

High

420959

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

0

High-throughput

0.279

Low

439033

YCIH
Uncharacterized protein YciH

1

0

High-throughput

0.279

Low

461852

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.279

Low

678234

AAS
Bifunctional protein Aas [Includes: 2-acylglycerophosphoethanolamine acyltransferase

1

0

High-throughput

0.279

Low

739455

ECPB
Probable fimbrial chaperone EcpB

1

0

High-throughput

0.279

Low

461556

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.253

Low

465405

MREB
Cell shape-determining protein MreB

1

0

High-throughput

0.253

Low

465845

PSTB
Phosphate import ATP-binding protein PstB

1

0

High-throughput

0.249

Low

739456

YAIT
Putative uncharacterized protein YaiT

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024