Protein: RS6
Small ribosomal subunit protein bS6 (30S ribosomal protein S6) [Cleaved into: Small ribosomal subunit protein bS6, fully modified isoform; Small ribosomal subunit protein bS6, non-modified isoform]

Gene: RS6, rpsF
Organism: Escherichia coli K-12
Interactions: 81
UniProt ID: P02358

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0022627 - cytosolic small ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

382549

RS18
Small ribosomal subunit protein bS18

3

2

High-throughput

0.845

High

382583

RNR
Ribonuclease R

2

0

High-throughput

0.748

High

382584

RNE
Ribonuclease E

2

0

High-throughput

0.748

High

382564

RLUC
Ribosomal large subunit pseudouridine synthase C

2

1

High-throughput

0.611

High

382582

ICLR
Transcriptional repressor IclR

2

1

High-throughput

0.611

High

382556

RHLB
ATP-dependent RNA helicase RhlB

2

1

High-throughput

0.588

High

382570

ALLR
HTH-type transcriptional repressor AllR

2

1

High-throughput

0.588

High

382557

SYT
Threonine--tRNA ligase

2

0

High-throughput

0.585

High

365795

RPOD
RNA polymerase sigma factor RpoD

2

0

High-throughput

0.585

High

382535

DNAJ
Chaperone protein DnaJ

2

0

High-throughput

0.585

High

382558

TMAR
Pole-localizer protein TmaR

2

0

High-throughput

0.585

High

382568

DPS
DNA protection during starvation protein

2

0

High-throughput

0.585

High

382581

SELB
Selenocysteine-specific elongation factor

2

0

High-throughput

0.585

High

382587

AIDB
Putative acyl-CoA dehydrogenase AidB

2

0

High-throughput

0.585

High

382591

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.585

High

382597

GMHBB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

2

0

High-throughput

0.585

High

382552

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.576

High

382575

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.576

High

382536

ACP
Acyl carrier protein

2

0

High-throughput

0.563

High

382545

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.563

High

382546

PGK
Phosphoglycerate kinase

2

0

High-throughput

0.563

High

382559

RPOB
DNA-directed RNA polymerase subunit beta

2

0

High-throughput

0.563

High

382562

MREB
Cell shape-determining protein MreB

2

0

High-throughput

0.563

High

382563

CSPC
Cold shock-like protein CspC

2

0

High-throughput

0.563

High

382565

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

382566

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

0

High-throughput

0.563

High

382600

NFI
Endonuclease V

2

0

High-throughput

0.563

High

382593

RLUB
Ribosomal large subunit pseudouridine synthase B

1

1

High-throughput

0.561

High

382554

UVRC
UvrABC system protein C

1

0

High-throughput

0.537

High

382532

ERA
GTPase Era

1

1

High-throughput

0.536

High

382585

MNME
tRNA modification GTPase MnmE

1

1

High-throughput

0.536

High

382531

UVRD
DNA helicase II

1

0

High-throughput

0.513

High

382539

MNMG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

1

0

High-throughput

0.513

High

382542

DNAK
Chaperone protein DnaK

1

0

High-throughput

0.513

High

382550

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

382589

PURNU
Purine nucleoside phosphorylase YfiH

1

0

High-throughput

0.513

High

382596

RL5
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

382601

ULAC
Ascorbate-specific PTS system EIIA component

1

0

High-throughput

0.513

High

382603

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.513

High

382534

RF2
Peptide chain release factor RF2

1

0

Small-scale

0.480

High

382599

YQJI
Transcriptional regulator YqjI

1

0

High-throughput

0.479

High

382607

DCYD
D-cysteine desulfhydrase

1

0

High-throughput

0.479

High

382608

YFFS
Uncharacterized protein YffS

1

0

High-throughput

0.479

High

382537

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

382540

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

382541

IHFB
Integration host factor subunit beta

1

0

High-throughput

0.464

High

382543

HTPG
Chaperone protein HtpG

1

0

High-throughput

0.464

High

382544

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

1

0

High-throughput

0.464

High

382561

DEAD
ATP-dependent RNA helicase DeaD

1

0

High-throughput

0.464

High

382567

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

382576

SPOT
Bifunctional

1

0

High-throughput

0.464

High

382577

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

382579

IBPA
Small heat shock protein IbpA

1

0

High-throughput

0.464

High

382595

LEPA
Elongation factor 4

1

0

High-throughput

0.464

High

382538

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.458

High

382547

PYRH
Uridylate kinase

1

0

High-throughput

0.458

High

382548

RL9
Large ribosomal subunit protein bL9

1

0

Small-scale

0.458

High

382560

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

382573

YOAB
RutC family protein YoaB

1

0

High-throughput

0.458

High

382574

NSRR
HTH-type transcriptional repressor NsrR

1

0

High-throughput

0.458

High

382578

YHBY
RNA-binding protein YhbY

1

0

High-throughput

0.458

High

382588

TKT2
Transketolase 2

1

0

High-throughput

0.458

High

382602

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

382605

RLMI
Ribosomal RNA large subunit methyltransferase I

1

0

High-throughput

0.458

High

382610

YQHD
NADPH-dependent aldehyde reductase YqhD

1

0

High-throughput

0.458

High

382594

TORZ
Trimethylamine-N-oxide reductase 2

1

1

High-throughput

0.457

High

382604

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.318

High

382553

YACL
UPF0231 protein YacL

2

0

High-throughput

0.307

High

382555

TRMB
tRNA

2

0

High-throughput

0.307

High

382571

FIMB
Type 1 fimbriae regulatory protein FimB

2

0

High-throughput

0.307

High

382533

DPO3X
DNA polymerase III subunit tau

1

0

High-throughput

0.279

Low

382569

EXBB
Biopolymer transport protein ExbB

1

0

High-throughput

0.261

Low

382572

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

382551

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

382580

RCSA
Transcriptional regulatory protein RcsA

1

0

High-throughput

0.253

Low

382586

PDEC
Probable cyclic di-GMP phosphodiesterase PdeC

1

0

High-throughput

0.249

Low

382590

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

0

High-throughput

0.249

Low

382592

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

382598

YQJD
Uncharacterized protein YqjD

1

0

High-throughput

0.249

Low

382606

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low

382609

GTRB
Prophage bactoprenol glucosyl transferase homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025