Protein: RL19
Large ribosomal subunit protein bL19 (50S ribosomal protein L19)

Gene: RL19, rplS
Organism: Escherichia coli K-12
Interactions: 139
UniProt ID: P0A7K6

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

492607

NUSA
Transcription termination/antitermination protein NusA

3

0

High-throughput

0.629

High

492593

IOJAP
Ribosomal silencing factor RsfS

1

2

High-throughput

0.625

High

444269

TOP1
DNA topoisomerase 1

2

1

High-throughput

0.612

High

492595

DBHB
DNA-binding protein HU-beta

2

1

High-throughput

0.611

High

492587

CSPA
Cold shock protein CspA

2

5

High-throughput

0.601

High

492575

RHLB
ATP-dependent RNA helicase RhlB

2

1

High-throughput

0.588

High

492576

SYT
Threonine--tRNA ligase

2

2

High-throughput

0.588

High

492581

CSPD
Cold shock-like protein CspD

2

5

High-throughput

0.588

High

492588

CSPC
Cold shock-like protein CspC

2

5

High-throughput

0.588

High

492590

RLUC
Ribosomal large subunit pseudouridine synthase C

2

2

High-throughput

0.588

High

492610

SPOT
Bifunctional

2

1

High-throughput

0.588

High

492617

SELB
Selenocysteine-specific elongation factor

2

2

High-throughput

0.588

High

492631

AIDB
Putative acyl-CoA dehydrogenase AidB

2

1

High-throughput

0.588

High

492637

RLUB
Ribosomal large subunit pseudouridine synthase B

2

2

High-throughput

0.588

High

492646

RLMB
23S rRNA

2

2

High-throughput

0.588

High

480528

GRPE
Protein GrpE

2

0

High-throughput

0.585

High

492612

SSB
Single-stranded DNA-binding protein

2

1

High-throughput

0.584

High

492570

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.576

High

492602

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

361737

PHSM
Maltodextrin phosphorylase

2

0

High-throughput

0.563

High

365804

RPOD
RNA polymerase sigma factor RpoD

2

0

High-throughput

0.563

High

368944

SYGA
Glycine--tRNA ligase alpha subunit

2

0

High-throughput

0.563

High

490850

HFQ
RNA-binding protein Hfq

2

0

High-throughput

0.563

High

491467

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

2

0

High-throughput

0.563

High

492118

HSLV
ATP-dependent protease subunit HslV

2

0

High-throughput

0.563

High

492586

ULAR
HTH-type transcriptional regulator UlaR

2

0

High-throughput

0.563

High

492592

YBCJ
Putative RNA-binding protein YbcJ

2

0

High-throughput

0.563

High

492597

ALLR
HTH-type transcriptional repressor AllR

2

0

High-throughput

0.563

High

492600

YIBL
Uncharacterized protein YibL

2

0

High-throughput

0.563

High

492651

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

2

0

High-throughput

0.563

High

492652

NFI
Endonuclease V

2

0

High-throughput

0.563

High

492618

TOP3
DNA topoisomerase 3

2

1

High-throughput

0.537

High

431292

PTRA
Protease 3

1

2

High-throughput

0.536

High

492415

RL11
Large ribosomal subunit protein uL11

1

1

High-throughput

0.536

High

492589

RL13
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

492611

RL17
Large ribosomal subunit protein bL17

1

1

High-throughput

0.536

High

490438

DEOB
Phosphopentomutase

1

0

High-throughput

0.513

High

490490

DTD
D-aminoacyl-tRNA deacylase

1

0

High-throughput

0.513

High

492605

FKBX
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

492608

PDXH
Pyridoxine/pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.513

High

492621

UBIG
Ubiquinone biosynthesis O-methyltransferase

1

0

High-throughput

0.513

High

492626

FLIS
Flagellar secretion chaperone FliS

1

0

High-throughput

0.513

High

492645

USPC
Universal stress protein C

1

0

High-throughput

0.513

High

492647

YHBS
Uncharacterized N-acetyltransferase YhbS

1

0

High-throughput

0.513

High

492672

ATOC
Regulatory protein AtoC

1

0

High-throughput

0.513

High

491876

NANE
Putative N-acetylmannosamine-6-phosphate 2-epimerase

1

0

High-throughput

0.493

High

492609

RELA
GTP pyrophosphokinase

1

1

High-throughput

0.489

High

492619

CYSA
Sulfate/thiosulfate import ATP-binding protein CysA

1

2

High-throughput

0.489

High

492632

YEHX
Glycine betaine uptake system ATP-binding protein YehX

1

2

High-throughput

0.489

High

473248

DNAJ
Chaperone protein DnaJ

1

1

High-throughput

0.484

High

490236

CLPP
ATP-dependent Clp protease proteolytic subunit

1

1

High-throughput

0.484

High

490947

IHFB
Integration host factor subunit beta

1

1

High-throughput

0.484

High

492582

CSPE
Cold shock-like protein CspE

1

5

High-throughput

0.484

High

492633

CBPA
Curved DNA-binding protein

1

1

High-throughput

0.484

High

492580

DARP
Dual-action ribosomal maturation protein DarP

1

0

High-throughput

0.479

High

492628

YBIB
Uncharacterized protein YbiB

1

0

High-throughput

0.479

High

492644

YHHX
Uncharacterized oxidoreductase YhhX

1

0

High-throughput

0.479

High

492650

YQJI
Transcriptional regulator YqjI

1

0

High-throughput

0.479

High

492660

DCYD
D-cysteine desulfhydrase

1

0

High-throughput

0.479

High

492664

HLDE
Bifunctional protein HldE [Includes: D-beta-D-heptose 7-phosphate kinase

1

0

High-throughput

0.479

High

492613

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

2

High-throughput

0.479

High

395102

DPO3E
DNA polymerase III subunit epsilon

1

0

High-throughput

0.464

High

490624

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.464

High

490659

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

490692

FIS
DNA-binding protein Fis

1

0

High-throughput

0.464

High

491003

DNAK
Chaperone protein DnaK

1

0

High-throughput

0.464

High

491524

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

491912

RPPH
RNA pyrophosphohydrolase

1

0

High-throughput

0.464

High

492054

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.464

High

492216

PYRH
Uridylate kinase

1

0

High-throughput

0.464

High

492571

TGT
Queuine tRNA-ribosyltransferase

1

0

High-throughput

0.464

High

492573

UVRC
UvrABC system protein C

1

0

High-throughput

0.464

High

492578

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.464

High

492583

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

492584

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

0

High-throughput

0.464

High

492585

DEAD
ATP-dependent RNA helicase DeaD

1

0

High-throughput

0.464

High

492596

HSLR
Heat shock protein 15

1

0

High-throughput

0.464

High

492603

MAP1
Methionine aminopeptidase

1

0

High-throughput

0.464

High

492606

SKP
Chaperone protein Skp

1

0

High-throughput

0.464

High

492614

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

492616

LPXB
Lipid-A-disaccharide synthase

1

0

High-throughput

0.464

High

492622

PNCB
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.464

High

492623

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

0

High-throughput

0.464

High

492635

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

492663

FADI
3-ketoacyl-CoA thiolase FadI

1

0

High-throughput

0.464

High

432113

APAH
Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]

1

0

High-throughput

0.458

High

492577

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.458

High

492579

YFBU
UPF0304 protein YfbU

1

0

High-throughput

0.458

High

492598

KPYK1
Pyruvate kinase I

1

0

High-throughput

0.458

High

492624

ACNA
Aconitate hydratase A

1

0

High-throughput

0.458

High

492648

QUEE
7-carboxy-7-deazaguanine synthase

1

0

High-throughput

0.458

High

492653

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

492662

5DNU
5'-deoxynucleotidase YfbR

1

0

High-throughput

0.458

High

492671

MENI
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

1

0

High-throughput

0.458

High

492674

YQHD
NADPH-dependent aldehyde reductase YqhD

1

0

High-throughput

0.458

High

492572

YEBC
Probable transcriptional regulatory protein YebC

1

2

High-throughput

0.457

High

492634

YADG
Uncharacterized ABC transporter ATP-binding protein YadG

1

1

High-throughput

0.437

High

491577

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.426

High

492638

USPF
Universal stress protein F

2

0

High-throughput

0.318

High

492641

YJJU
Uncharacterized protein YjjU

2

0

High-throughput

0.318

High

492569

RNPA
Ribonuclease P protein component

2

0

High-throughput

0.307

High

492599

FIMB
Type 1 fimbriae regulatory protein FimB

2

0

High-throughput

0.307

High

492627

HOLC
DNA polymerase III subunit chi

2

0

High-throughput

0.307

High

492654

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

492655

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

2

0

High-throughput

0.307

High

418553

NLPA
Lipoprotein 28

1

0

High-throughput

0.279

Low

492591

WZB
Low molecular weight protein-tyrosine-phosphatase Wzb

1

0

High-throughput

0.279

Low

492630

CBRC
UPF0167 protein CbrC

1

0

High-throughput

0.279

Low

492668

YDHW
Uncharacterized protein YdhW

1

0

High-throughput

0.279

Low

492670

YFCH
Epimerase family protein YfcH

1

0

High-throughput

0.279

Low

492601

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

492659

YNJB
Protein YnjB

1

0

High-throughput

0.261

Low

450003

MALT
HTH-type transcriptional regulator MalT

1

0

High-throughput

0.253

Low

491778

MOAC
Cyclic pyranopterin monophosphate synthase

1

0

High-throughput

0.253

Low

492020

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

492574

TRMB
tRNA

1

0

High-throughput

0.253

Low

492594

KDTA
3-deoxy-D-manno-octulosonic acid transferase

1

0

High-throughput

0.253

Low

492604

DMA
DNA adenine methylase

1

0

High-throughput

0.253

Low

492615

RCSA
Transcriptional regulatory protein RcsA

1

0

High-throughput

0.253

Low

492620

MURG
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

1

0

High-throughput

0.253

Low

492625

RIBD
Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase

1

0

High-throughput

0.253

Low

393851

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

393961

TONB
Protein TonB

1

0

High-throughput

0.249

Low

492629

YICH
AsmA family protein YicH

1

0

High-throughput

0.249

Low

492636

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

492639

YJDJ
Uncharacterized protein YjdJ

1

0

High-throughput

0.249

Low

492640

BTST
Pyruvate/proton symporter BtsT

1

0

High-throughput

0.249

Low

492642

KDSD
Arabinose 5-phosphate isomerase KdsD

1

0

High-throughput

0.249

Low

492643

DXR
1-deoxy-D-xylulose 5-phosphate reductoisomerase

1

0

High-throughput

0.249

Low

492649

YQJD
Uncharacterized protein YqjD

1

0

High-throughput

0.249

Low

492656

YNCE
Uncharacterized protein YncE

1

0

High-throughput

0.249

Low

492657

YNEG
Uncharacterized protein YneG

1

0

High-throughput

0.249

Low

492658

YNHG
Probable L,D-transpeptidase YnhG

1

0

High-throughput

0.249

Low

492661

YEGH
UPF0053 protein YegH

1

0

High-throughput

0.249

Low

492665

GTRB
Prophage bactoprenol glucosyl transferase homolog

1

0

High-throughput

0.249

Low

492666

GLSA1
Glutaminase 1

1

0

High-throughput

0.249

Low

492667

YDJL
Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjL

1

0

High-throughput

0.249

Low

492669

YBAY
Uncharacterized lipoprotein YbaY

1

0

High-throughput

0.249

Low

492673

UACT
Uric acid transporter UacT

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025